Results 121 to 130 of about 890,691 (262)

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source

Lipid-Laden Macrophages in Cannabinoid Oil Vaping Associated Lung Injury [PDF]

The American Journal of Medicine, 2020
Kulothungan Gunasekaran, Venkat Rajasurya, Arul Chandran, Joe Devasahayam   +3 more
openaire   +2 more sources

Cobalt Single‐Atom Nanozyme for Enhanced Intestinal Radioprotection and Tumor Radiosensitization via Bidirectional ROS Modulation

Advanced Science, EarlyView.
Orally administered, pH‐responsive Co‐SAN exerts dual functions: in the alkaline intestinal milieu, it scavenges reactive oxygen species (ROS) and suppresses the PI3K/AKT pathway and NETs formation, thus providing radioprotection; whereas in the acidic tumor microenvironment, it generates ROS and alleviates hypoxia, thereby enhancing radiosensitization.
Shengqi Yin, Junjie Li, Yishu Zou, Yang Liu, Yilin Zheng, Lu Yu, Wanying Zheng, Yajun Zou, Zehui Zhang, Tao Li, Peiqun Yin, Jianlin Zhang, Yuen Wu, Yi Ding   +13 more
wiley   +1 more source

Ausführliche Erzehlung von zwey merckwürdigen Entzückungen, Welche ein Mann im Halberstädtischen Dorfe Hornhausen, Johann Schwerdtfeger genandt, Im Nov. 1733. wenig Tage vor seinem Tode gehabt : Darinnen er sich auf dem Weg zum Himmel und vor dem Gerichte Gottes, seiner Einbildung nach, befunden, Wie solche auf Ihro Königl. Maj. in Preußen ... Befehl ein gewisser Prediger, Nahmens Kern, einberichtet ; Nach dem Halberstädtischen wahren Original

Vorlageform des Erscheinungsvermerks: Dresden, Im Mohrenthalischen Laden auf der Frauen-Gasse ...
Kern, Gottfried
core   +1 more source

Traditional processing unlocks anti-atherogenic potential of perilla fruit via PPAR-γ activation by luteolin

Bioresources and Bioprocessing
The accumulation of foam cells, lipid-laden macrophages in atherosclerotic plaques, is a hallmark of cardiovascular disease progression. These cells contribute to chronic inflammation and plaque instability, underscoring the need for novel therapeutic ...
Yiqi Yan, Tian Xie, Ran An, Guangzhe Yao, Ming Huang, Ke Xiong   +5 more
doaj   +1 more source

A Disulfide‐Sticker Strategy for Marine Adhesive Coatings: From Deciphering Self‐Assembly Mechanism to Functional Application in Hair Regeneration

Advanced Science, EarlyView.
A disulfide‐sticker strategy, coupled with Ca2+ coordination, drives the hierarchical self‐assembly of a recombinant scallop adhesive protein into fishnet‐like nanostructures, affording a coating with versatile wet adhesion and intrinsic antioxidant activity. This biocompatible coating markedly promotes hair regeneration by activating follicular niches,
Lulu Wang, Juan Yang, Xin Jiang, Zhanghui Zheng, Hongyu Wei, Na Li, Xiangqiang Chu, Weizhi Liu   +7 more
wiley   +1 more source

Lipid-Laden Macrophages Are Not Diagnostic of Pulmonary Alveolar Proteinosis Syndrome and Can Indicate Lung Injury. [PDF]

Am J Respir Crit Care Med, 2020
McCarthy C, Keane MP, Fabre A.
europepmc   +1 more source

HMGCR‐Driven Cholesterol Metabolism Promotes Osteoarthritis Progression by Accelerating Synovial Fibroblast Senescence

Advanced Science, EarlyView.
In the pathological context of osteoarthritis (OA), the phosphorylation of AKT1 at Ser473 enhances its binding to Lys140 of Insig1, which facilitates the formation of AKT1–Insig1 complex. Subsequently, the activation of AKT1 promotes the phosphorylation of Insig1 at Ser189, potentially enhancing the dissociation of Insig1 from sterol regulatory element‑
Xiaoqi Zhang, Siru Zhou, Xi Liu, Wei Xiang, Xiuqin Peng, Yu Tian, Song Li, Hailin Wang, Bo Liao, Shunzheng Fang, Runze Jin, Jinhui Wu, Chuanqing Bai, Wei Zhang, Bo Huang, Bingfei Li, Lifeng Chen, Lin Chen, Bin Zhang, Zhenhong Ni   +19 more
wiley   +1 more source

Int Immunopharmacol [PDF]

Uniquely positioned as sentinel cells constantly exposed to the environment, pulmonary macrophages are vital for the maintenance of the lung lining.

core  

Die Manier, Wie man sich in der Conversation, sowol Mit Hohen, vornehmen Personen, seines Gleichen und Frauenzimmer, bescheiden und klüglich verhalten, und zu einer Galanten Conduite gelangen möge : So unlängst, von einem Hochgelehrten Mann, auf einer berühmten Universität, einigen Herren Studiosis in einem Collegio Conversatorio fürgetragen, und zu gemeinem Besten anjetzo zum Druck befördert worden

Titelbl. in Rot- und SchwarzdruckVorlageform des Erscheinungsvermerks: Nürnberg und Leipzig, Jn den Felßeckerischen Buch-Laden. [1714.] - Erscheinungsjahr im Ex.
unknown
core   +1 more source