Results 1 to 10 of about 24,961,776 (358)
Lipid nanoparticles for mRNA delivery
Nature Reviews Materials, 2021 Messenger RNA (mRNA) has emerged as a new category of therapeutic agent to prevent and treat various diseases. To function in vivo, mRNA requires safe, effective and stable delivery systems that protect the nucleic acid from degradation and that allow ...
Xucheng Hou +2 more
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Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease
Cellular and Molecular Life Sciences, 2018 Non-alcoholic fatty liver disease (NAFLD) is currently the world’s most common liver disease, estimated to affect up to one-fourth of the population.
David Højland Ipsen +2 more
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Journal of Clinical and Scientific Research, 2021 Gram-negative bacteria show more drug-resistant than Gram-positive bacteria due to unique structural attribute and cause significant morbidity and mortality across the globe.
Chiranjeevi Pasala +6 more
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Endotoxin-Free Stx2B-C-CPE Vaccine and Its Optimized Adjuvant Regimen for Preventing Food Poisoning
Frontiers in Bioscience-Landmark, 2023 Background: Clostridium perfringens and Shiga toxin (Stx)-producing Escherichia coli (STEC) are common causes of food poisoning. We previously demonstrated the efficacy of Stx2B-C-CPE, a fusion protein of the C-terminal region of C.
Koji Hosomi +12 more
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The mystery of membrane organization: composition, regulation and roles of lipid rafts
Nature Reviews Molecular Cell Biology, 2017 Erdinc Sezgin +2 more
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Children, 2021 Polycystic ovary syndrome (PCOS) is the most common endocrine condition affecting 6–18% of adolescents and is strongly associated with obesity and cardiovascular risk factors, enhancing the risk of atherosclerosis.
Anastasia Garoufi +6 more
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Lipid A and Anti-Lipid A [PDF]
Infection and Immunity, 1979 Lipid A in free form, in crude antigen preparations, and on Formalin-treated Escherichia coli and Salmonella minnesota R595 was employed in studies of its antigenic composition, immunogenicity, and availability on gram-negative bacteria.
Inger Mattsby-Baltzer, Bertil Kaijser
openaire +3 more sources
Prospective assessment of the repercussions on the lipid profile of surgeries involving liposuction and dermolipectomies [PDF]
Revista Brasileira de Cirurgia Plástica, 2019 Introduction: Liposuction associated with dermolipectomies is the most commonly performed surgical procedure in plastic surgery. Although regarded as an extremely safe surgery, some considerations must be taken on the possible metabolic effects of these ...
Leonardo David Pires Barcelos +6 more
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Children, 2022 Pediatric chronic kidney disease (CKD) patients, as well as kidney transplant patients, are at an increased risk of developing cardiovascular disease.
Anastasia Garoufi +9 more
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Vaccines, 2020 Based on a live attenuated Yersinia pestis KIM10(pCD1Ap) strain (Pgm−, pPCP1−), we attempted to engineer its lipid A species to achieve improvement of immunogenicity and safety. A mutant strain designated as YPS19(pCD1Ap), mainly synthesizing
Xiuran Wang, Amit K. Singh, Wei Sun
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