Increased lymphocyte transport by lipid absorption in rat mesenteric lymphatics
The effect of olive oil administration on lymphocyte transport through mesenteric lymphatics was examined to see the possible involvement of nutritional absorption in lymphocyte traffic from the intestinal mucosa.
al. et +10 more
core +1 more source
Drug-excipient-shell interactions using thermoplastic starch-based capsules for oral lipid-based drug delivery [PDF]
Worldwide, gelatin has been used in the rotary die process as a shell-forming material of soft capsules due to its unique physicochemical properties.
Misic, Zdravka
core +1 more source
Engineering Antigen Density on M13 Bacteriophage for Personalized Nanovaccine
Increasing antigen density on the phage capsid impacts phage uptake and antigen cross‐presentation by antigen‐presenting cells, leading to enhanced activation of antitumor CD8+ T cells in the draining lymph nodes. These activated CD8+ T cells subsequently recognize the antigen‐expressing tumors and mediate their specific cytotoxic killing, thereby ...
Shengnan Huang +7 more
wiley +1 more source
Atom‐Efficient Cerium‐Based Molecular Cages as Biocompatible Reactive Oxygen Scavengers
Discrete mixed‐valent cerium molecular cages organize accessible redox centers within confined coordination environments and scavenge superoxide, hydrogen peroxide, and hydroxyl radicals. Encapsulation of the lead cage in an ROS‐responsive DTP nanoplatform enables lesion‐associated delivery, attenuates macrophage oxidative stress and inflammation, and ...
Chao Li +9 more
wiley +1 more source
Dietary fat undergoes digestion and absorption before entering enterocytes, where lipids are re-esterified and packaged into chylomicrons for lymphatic transport.
Jie Yin +4 more
doaj +1 more source
mTOR Impacts Metabolic Health by Regulating Dietary Lipid Absorption
Mechanistic target of rapamycin (mTOR) senses amino acids; however, its role in lipid metabolism is less established. Organismal lipid requirements are largely met through dietary intake.
Batista-Gonzalez, Ana
core
Hemocompatible Glycogen‐Tissue Plasminogen Activator Complexes for Enhanced Blood Clot Dissolution
Glycogen–heparin‐cRGD nanoparticles enable targeted delivery of tissue plasminogen activator (tPA) to thrombi through activated platelet recognition. The hemocompatible hybrids minimize interactions with blood and immune cells while retaining enzymatic biodegradability.
Nadiia Davydiuk +6 more
wiley +1 more source
Chylomicrons Regulate Lacteal Permeability and Intestinal Lipid Absorption. [PDF]
Zarkada G +21 more
europepmc +1 more source
Lipid extraction and CO2 capture with switchable polarity solvent
In this study, lipid extraction and CO2 capture are combined using N, N-dimethylcyclohexylamine (DMCHA) as switchable polarity solvent. The effects of operation parameters are discussed according to the CO2 absorption/desorption and lipid/DMCHA recovery ...
Kejing Wu +5 more
doaj +1 more source
Increasing Lipid Nanoparticle mRNA Copy Number Improves Transfection Potency
As lipid nanoparticle (LNP) systems are the leading platform for in vivo nucleic acid delivery, improving transfection potency of these systems is of considerable interest. In this work, we explored a post‐mixing formulation method involving a two‐step buffer exchange that increased the number of mRNA copies within each LNP while reducing the number of
Yao Zhang +12 more
wiley +1 more source

