Results 1 to 10 of about 484,984 (311)

Enhancing microalgal lipid accumulation for biofuel production [PDF]

Frontiers in Microbiology, 2022
Microalgae have high lipid accumulation capacity, high growth rate and high photosynthetic efficiency which are considered as one of the most promising alternative sustainable feedstocks for producing lipid-based biofuels.
Zhi Zhu, Zhi Zhu, Zhi Zhu, Zhi Zhu, Jing Sun, Yun Fa, Xufeng Liu, Peter Lindblad   +7 more
doaj   +4 more sources

Oral Prevotella induces fat taste impairment, visceral lipid accumulation and insulin resistance by downregulating Hedgehog signaling in taste buds [PDF]

Journal of Oral Microbiology
Background Fat taste impairment has been implicated in visceral lipid accumulation and insulin resistance, with emerging evidence linking it to the oral microbiota.
Xiaohuan Liu, Jiehan Zhang, Yi He, Qiao Zhang, Shuaixian Du, Tianshu Zeng, Jiaoyue Zhang, Hao Zhang, Han Luo, Huiqing Li, Ying Wang, Miaomiao Peng, Nan Zhang, Qi Chen, Hantao Huang, Ping Wang, Lulu Chen, Xiang Hu   +17 more
doaj   +2 more sources

LipiD-QuanT: a novel method to quantify lipid accumulation in live cells[S] [PDF]

Journal of Lipid Research, 2015
Lipid droplets (LDs) are the main storage organelles for triglycerides. Elucidation of lipid accumulation mechanisms and metabolism are essential to understand obesity and associated diseases. Adipogenesis has been well studied in murine 3T3-L1 and human
Hilal Varinli, Megan J. Osmond-McLeod, Peter L. Molloy, Pascal Vallotton   +3 more
doaj   +2 more sources

Lipid Droplet Accumulation Promotes RPE Dysfunction [PDF]

International Journal of Molecular Sciences, 2022
Non-exudative age-related macular degeneration (AMD) is an irreversibly progressive retinal degenerative disease characterized by dysfunction and loss of retinal pigment epithelium (RPE). It has been suggested that impaired phagocytosis of the RPE is involved in the progression of non-exudative AMD, but the mechanism is not fully clear.
Tomohiro Yako, Wataru Otsu, Shinsuke Nakamura, Masamitsu Shimazawa, Hideaki Hara   +4 more
openaire   +2 more sources

Astrocytes in stress accumulate lipid droplets [PDF]

Glia, 2021
AbstractWhen the brain is in a pathological state, the content of lipid droplets (LDs), the lipid storage organelles, is increased, particularly in glial cells, but rarely in neurons. The biology and mechanisms leading to LD accumulation in astrocytes, glial cells with key homeostatic functions, are poorly understood.
Tina Smolič, Petra Tavčar, Anemari Horvat, Urška Černe, Ana Halužan Vasle, Larisa Tratnjek, Mateja Erdani Kreft, Nicole Scholz, Maja Matis, Toni Petan, Robert Zorec, Nina Vardjan   +11 more
openaire   +2 more sources

CYP1B1 Mediates Cigarette Smoke-Induced Lipid Accumulation in Alveolar Type 2 Cells. [PDF]

FASEB J
Zhu Y, Gamare S, Polverino F, Owen CA, Somanath PR, Wang X, Zhang D.   +6 more
europepmc   +2 more sources

Swertia mussotii prevents high-fat diet-induced non-alcoholic fatty liver disease in rats by inhibiting expression the TLR4/MyD88 and the phosphorylation of NF-κB

Pharmaceutical Biology, 2022
Context Swertia mussotii Franch. (Gentianaceae) is a source of the traditional Tibetan medicine, ZangYinChen, and is used to treat chronic hepatitis and many types of jaundice.Objective This study explored the therapeutic effects and mechanism of S ...
Ming Dong Si, Meng Wu, Xi Zhen Cheng, Zhi Hong Ma, Yu Guang Zheng, Jing Li, Si Li, Yong Xing Song, Donglai Ma   +8 more
doaj   +1 more source

ACSM5 inhibits ligamentum flavum hypertrophy by regulating lipid accumulation mediated by FABP4/PPAR signaling pathway

Biology Direct, 2023
Background Ligamentum flavum (LF) hypertrophy is the main cause of lumbar spinal canal stenosis (LSCS). Previous studies have shown that LF hypertrophy tissue exhibits abnormal lipid accumulation, but the regulatory mechanism remains unclear.
Yanlin Cao, Jianjun Li, Sujun Qiu, Songjia Ni, Yang Duan   +4 more
doaj   +1 more source

Vicious cycle of lipid peroxidation and iron accumulation in neurodegeneration

Neural Regeneration Research, 2023
Lipid peroxidation and iron accumulation are closely associated with neurodegenerative diseases, such as Alzheimer’s, Parkinson’s, and Huntington’s diseases, or neurodegeneration with brain iron accumulation disorders.
Irene Villalón-García, Suleva Povea-Cabello, Mónica Álvarez-Córdoba, Marta Talaverón-Rey, Juan M Suárez-Rivero, Alejandra Suárez-Carrillo, Manuel Munuera-Cabeza, Diana Reche-López, Paula Cilleros-Holgado, Rocío Piñero-Pérez, José A Sánchez-Alcázar   +10 more
doaj   +1 more source

BRAF Modulates Lipid Use and Accumulation

Cancers, 2022
There is increasing evidence that oxidative metabolism and fatty acids play an important role in BRAF-driven tumorigenesis, yet the effect of BRAF mutation and expression on metabolism is poorly understood. We examined how BRAF mutation and expression modulates metabolite abundance.
Jacqueline A. Turner, Emily L. Paton, Robert Van Gulick, Davide Stefanoni, Francesca Cendali, Julie Reisz, Richard P. Tobin, Martin McCarter, Angelo D’Alessandro, Raul M. Torres, William A. Robinson, Kasey L. Couts, Isabel R. Schlaepfer   +12 more
openaire   +2 more sources