Results 1 to 10 of about 858,616 (357)

Oral Prevotella induces fat taste impairment, visceral lipid accumulation and insulin resistance by downregulating Hedgehog signaling in taste buds [PDF]

Journal of Oral Microbiology
Background Fat taste impairment has been implicated in visceral lipid accumulation and insulin resistance, with emerging evidence linking it to the oral microbiota.
Xiaohuan Liu, Jiehan Zhang, Yi He, Qiao Zhang, Shuaixian Du, Tianshu Zeng, Jiaoyue Zhang, Hao Zhang, Han Luo, Huiqing Li, Ying Wang, Miaomiao Peng, Nan Zhang, Qi Chen, Hantao Huang, Ping Wang, Lulu Chen, Xiang Hu   +17 more
doaj   +2 more sources

Swertia mussotii prevents high-fat diet-induced non-alcoholic fatty liver disease in rats by inhibiting expression the TLR4/MyD88 and the phosphorylation of NF-κB

Pharmaceutical Biology, 2022
Context Swertia mussotii Franch. (Gentianaceae) is a source of the traditional Tibetan medicine, ZangYinChen, and is used to treat chronic hepatitis and many types of jaundice.Objective This study explored the therapeutic effects and mechanism of S ...
Ming Dong Si, Meng Wu, Xi Zhen Cheng, Zhi Hong Ma, Yu Guang Zheng, Jing Li, Si Li, Yong Xing Song, Donglai Ma   +8 more
doaj   +1 more source

ACSM5 inhibits ligamentum flavum hypertrophy by regulating lipid accumulation mediated by FABP4/PPAR signaling pathway

Biology Direct, 2023
Background Ligamentum flavum (LF) hypertrophy is the main cause of lumbar spinal canal stenosis (LSCS). Previous studies have shown that LF hypertrophy tissue exhibits abnormal lipid accumulation, but the regulatory mechanism remains unclear.
Yanlin Cao, Jianjun Li, Sujun Qiu, Songjia Ni, Yang Duan   +4 more
doaj   +1 more source

Vicious cycle of lipid peroxidation and iron accumulation in neurodegeneration

Neural Regeneration Research, 2023
Lipid peroxidation and iron accumulation are closely associated with neurodegenerative diseases, such as Alzheimer’s, Parkinson’s, and Huntington’s diseases, or neurodegeneration with brain iron accumulation disorders.
Irene Villalón-García, Suleva Povea-Cabello, Mónica Álvarez-Córdoba, Marta Talaverón-Rey, Juan M Suárez-Rivero, Alejandra Suárez-Carrillo, Manuel Munuera-Cabeza, Diana Reche-López, Paula Cilleros-Holgado, Rocío Piñero-Pérez, José A Sánchez-Alcázar   +10 more
doaj   +1 more source

Puerarin Prevents Bisphenol S Induced Lipid Accumulation by Reducing Liver Lipid Synthesis and Promoting Lipid Metabolism in C57BL/6J Mice

Toxics, 2023
Bisphenol S (BPS) is an environmental pollutant that can accumulate in the human body and cause harm. Puerarin (PUE) is a flavonoid with anti-inflammatory and antioxidant effects.
Zi-Yao Wu, Li Luo, Ya-Qi Kan, Mei-Lin Qin, Hai-Ting Li, Qing-Zhi He, Huai-Cai Zeng   +6 more
doaj   +1 more source

Selenium reduces hepatopancreas lipid accumulation of grass carp (Ctenopharyngodon idella) fed high-fat diet via lipophagy activation

Animal Nutrition, 2023
It has been reported that selenium (Se) can reduce hepatopancreas lipid accumulation induced by high-fat diet. However, its mechanism is still unknown.
Xiaotian Zhang, Haibo Yu, Xianfang Yan, Pengju Li, Chi Wang, Cheng Zhang, Hong Ji   +6 more
doaj   +1 more source

Comparative proteomics profile of lipid-cumulating oleaginous yeast: an iTRAQ-coupled 2-D LC-MS/MS analysis. [PDF]

PLoS ONE, 2013
Accumulation of intracellular lipid in oleaginous yeast cells has been studied for providing an alternative supply for energy, biofuel. Numerous studies have been conducted on increasing lipid content in oleaginous yeasts.
Jiahua Shi, Huixing Feng, Jaslyn Lee, Wei Ning Chen   +3 more
doaj   +1 more source

Accumulation of Geosmin and 2-methylisoborneol in European Whitefish Coregonus Lavaretus and Rainbow Trout Oncorhynchus Mykiss in RAS [PDF]

, 2020
Geosmin (GSM) and 2-methylisoborneol (MIB)-induced off-flavors can cause serious problems in a recirculating aquaculture system (RAS), such as delayed harvest and increased production costs, but also damage producers’ reputation.
Kaseva, Janne, Koskela, Juha, Lindholm-Lehto, Petra, Vielma, Jouni   +3 more
core   +1 more source

HILPDA Uncouples Lipid Droplet Accumulation in Adipose Tissue Macrophages from Inflammation and Metabolic Dysregulation

Cell Reports, 2020
Summary: Obesity leads to a state of chronic, low-grade inflammation that features the accumulation of lipid-laden macrophages in adipose tissue. Here, we determined the role of macrophage lipid-droplet accumulation in the development of obesity-induced ...
Xanthe A.M.H. van Dierendonck, Montserrat A. de la Rosa Rodriguez, Anastasia Georgiadi, Frits Mattijssen, Wieneke Dijk, Michel van Weeghel, Rajat Singh, Jan Willem Borst, Rinke Stienstra, Sander Kersten   +9 more
doaj   +1 more source

Increased FAT/CD36 cycling and lipid accumulation in myotubes derived from obese type 2 diabetic patients. [PDF]

PLoS ONE, 2011
BACKGROUND: Permanent fatty acid translocase (FAT/)CD36 relocation has previously been shown to be related to abnormal lipid accumulation in the skeletal muscle of type 2 diabetic patients, however mechanisms responsible for the regulation of FAT/CD36 ...
Celine Aguer, Marc Foretz, Louise Lantier, Sophie Hebrard, Benoit Viollet, Jacques Mercier, Magali Kitzmann   +6 more
doaj   +1 more source