Results 111 to 120 of about 3,287,800 (353)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Choline supplementation prevents diet induced gut mucosa lipid accumulation in post-smolt Atlantic salmon (Salmo salar L.)

BMC Veterinary Research, 2020
Background Various intestinal morphological alterations have been reported in cultured fish fed diets with high contents of plant ingredients. Since 2000, salmon farmers have reported symptoms indicating an intestinal problem, which we suggest calling ...
Anne Kristine G. Hansen, Trond M. Kortner, Aleksei Krasnov, Ingemar Björkhem, Michael Penn, Åshild Krogdahl   +5 more
doaj   +1 more source

Nitrogen starvation induced oxidative stress in an oil-producing green alga Chlorella sorokiniana C3. [PDF]

PLoS ONE, 2013
Microalgal lipid is one of the most promising feedstocks for biodiesel production. Chlorella appears to be a particularly good option, and nitrogen (N) starvation is an efficient environmental pressure used to increase lipid accumulation in Chlorella ...
Yun-Ming Zhang, Hui Chen, Chen-Liu He, Qiang Wang   +3 more
doaj   +1 more source

Growth and lipid accumulation by different nutrients in the microalga Chlamydomonas reinhardtii

Biotechnology for Biofuels, 2018
BackgroundIndividual nutrient depletion is widely used to induce lipid accumulation in microalgae, which also causes cell growth inhibition and decreases the total biomass.
Lei Yang, Jun Chen, S. Qin, Min Zeng, Yongguang Jiang, Lan Hu, Peng Xiao, Wenlong Hao, Zhangli Hu, A. Lei, Jiangxin Wang   +10 more
semanticscholar   +1 more source

The effects of exogenous lipid on THP-1 cells : an in vitro model of airway aspiration? [PDF]

, 2017
Chronic inflammatory diseases of the airways are associated with gastro-oesophageal reflux (GOR) and aspiration events. The observation of lipid laden macrophages (LLM) within the airway may indicate aspiration secondary to GOR.
Adams, Ahrens, Anderson, Greenman, Nakahira, Pacheco-Galván, Porcheray   +6 more
core   +2 more sources

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Association between lipid accumulation products and stress urinary incontinence: a cross-sectional study from NHANES 2005 to 2018

Lipids in Health and Disease
Background Stress urinary incontinence (SUI), a common disorder of the pelvic floor, often results in anxiety, poor quality of life, and psychological issues among its sufferers.
JiHang Li, Dong Wang, Hu Tian, JianKun Yang, Hui Xia, WenBin Guo   +5 more
doaj   +1 more source

Influence of Nitrogen Limitation on Lipid Accumulation and EPA and DHA Content in Four Marine Microalgae for Possible Use in Aquafeed

Frontiers in Marine Science, 2019
Microalgae are regarded as a promising alternative that can replace fishmeal and fish oil in aquaculture. Under N-limitation, many microalgae species change their carbon storage patterns in favor of neutral lipids (NLs) mainly in the form of ...
Xinxin Wang, Hilde Karoline Fosse, Keshuai Li, M. S. Chauton, O. Vadstein, K. Reitan   +5 more
semanticscholar   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Noggin depletion in adipocytes promotes obesity in mice. [PDF]

, 2019
ObjectiveObesity has increased to pandemic levels and enhanced understanding of adipose regulation is required for new treatment strategies. Although bone morphogenetic proteins (BMPs) influence adipogenesis, the effect of BMP antagonists such as Noggin ...
Blázquez-Medela, Ana M, Boström, Kristina I, Fogelman, Alan M, Guo, Yina, Jumabay, Medet, Lusis, Aldons J, Rajbhandari, Prashant, Reue, Karen, Sallam, Tamer, Tontonoz, Peter, Vergnes, Laurent, Wu, Xiuju, Yao, Jiayi, Yao, Yucheng, Zhang, Li   +14 more
core   +1 more source