Results 11 to 20 of about 3,287,800 (353)

Role of Lipid Accumulation and Inflammation in Atherosclerosis: Focus on Molecular and Cellular Mechanisms

open access: yesFrontiers in Cardiovascular Medicine, 2021
Atherosclerosis is a chronic lipid-driven and maladaptive inflammatory disease of arterial intima. It is characterized by the dysfunction of lipid homeostasis and signaling pathways that control the inflammation.
Khojasteh Malekmohammad   +2 more
semanticscholar   +1 more source

Lipid Accumulation Induced by APOE4 Impairs Microglial Surveillance of Neuronal-Network Activity

open access: yesbioRxiv, 2022
Apolipoprotein E4 (APOE4) is the greatest known genetic risk factor for developing late- onset Alzheimer’s disease and its expression in microglia is associated with pro- inflammatory states.
Matheus B. Victor   +15 more
semanticscholar   +1 more source

BRAF Modulates Lipid Use and Accumulation

open access: yesCancers, 2022
There is increasing evidence that oxidative metabolism and fatty acids play an important role in BRAF-driven tumorigenesis, yet the effect of BRAF mutation and expression on metabolism is poorly understood. We examined how BRAF mutation and expression modulates metabolite abundance.
Jacqueline A. Turner   +12 more
openaire   +2 more sources

Puerarin Prevents Bisphenol S Induced Lipid Accumulation by Reducing Liver Lipid Synthesis and Promoting Lipid Metabolism in C57BL/6J Mice

open access: yesToxics, 2023
Bisphenol S (BPS) is an environmental pollutant that can accumulate in the human body and cause harm. Puerarin (PUE) is a flavonoid with anti-inflammatory and antioxidant effects.
Zi-Yao Wu   +6 more
doaj   +1 more source

Lipid metabolism and accumulation in oilseed crops [PDF]

open access: yesOCL, 2021
Triacylglycerols (TAGs) serve as the most important storage form of energy and carbon in eukaryotic cells and thus are one of the fundamental macronutrients for animal and human diet. They are also used as a major feedstock for diverse industrial and energetic sectors due to their high energy density. Oilseed crops represent the most valuable source of
Miklaszewska, Magdalena   +3 more
openaire   +4 more sources

Human resistin promotes macrophage lipid accumulation [PDF]

open access: yesDiabetologia, 2006
The gene encoding resistin/FIZZ3 (found in inflammatory zone 3), which is denoted by the gene symbol RETN in humans and Retn in mice, belongs to a new gene family of small cysteine-rich secretory proteins, called ‘resistin-like molecules’, originally discovered in a search for adipocytederived molecules linking obesity and insulin-resistant diabetes [1]
Rae, C., Graham, Annette
openaire   +2 more sources

Selenium reduces hepatopancreas lipid accumulation of grass carp (Ctenopharyngodon idella) fed high-fat diet via lipophagy activation

open access: yesAnimal Nutrition, 2023
It has been reported that selenium (Se) can reduce hepatopancreas lipid accumulation induced by high-fat diet. However, its mechanism is still unknown.
Xiaotian Zhang   +6 more
doaj   +1 more source

Apigenin ameliorates hepatic lipid accumulation by activating the autophagy-mitochondria pathway

open access: yesJournal of Food and Drug Analysis, 2021
Apigenin, a flavonoid isolated from plants, provides protection against non-alcoholic fatty liver disease. However, the mechanism by which apigenin decreases lipid accumulation in the liver is unclear.
Man-Chen Hsu   +4 more
semanticscholar   +1 more source

Accumulation of Geosmin and 2-methylisoborneol in European Whitefish Coregonus Lavaretus and Rainbow Trout Oncorhynchus Mykiss in RAS [PDF]

open access: yes, 2020
Geosmin (GSM) and 2-methylisoborneol (MIB)-induced off-flavors can cause serious problems in a recirculating aquaculture system (RAS), such as delayed harvest and increased production costs, but also damage producers’ reputation.
Kaseva, Janne   +3 more
core   +1 more source

HILPDA Uncouples Lipid Droplet Accumulation in Adipose Tissue Macrophages from Inflammation and Metabolic Dysregulation

open access: yesCell Reports, 2020
Summary: Obesity leads to a state of chronic, low-grade inflammation that features the accumulation of lipid-laden macrophages in adipose tissue. Here, we determined the role of macrophage lipid-droplet accumulation in the development of obesity-induced ...
Xanthe A.M.H. van Dierendonck   +9 more
doaj   +1 more source

Home - About - Disclaimer - Privacy