Results 31 to 40 of about 484,984 (311)
Journal of Lipid Research, 1998 Synthesis and accumulation of the recently identified prostaglandin F2α receptor regulatory protein (FPRP) was found to correlate closely with lipid droplet accumulation by 3T3-L1 preadipose cells.
D.J. Orlicky +3 more
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Naringenin inhibits lipid accumulation by activating the AMPK pathway in vivo and vitro
Food Science and Human Wellness, 2023 The aim of this study was to explore the lipid-lowering effect of naringenin and the underlying mechanism in high-fat-diet-fed SD rats and 3T3-L1 cells. In this study, SD rats were divided into the normal chow diet group (NCD), high fat diet group (HFD),
Xiaoyu Cai +7 more
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Targeting MicroRNAs to Limit Myocardial Lipid Accumulation [PDF]
Circulation Research, 2015 Obesity and type 2 diabetes mellitus are major health concerns, with the incidence rapidly rising in the world. Among their many complications is an increased risk of developing heart failure.1,2 This increased incidence of heart failure in obese and diabetic individual occurs even when corrected for the increased prevalence of hypertension and ...
Gary D, Lopaschuk, John R, Ussher
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Biochemistry and Biophysics Reports, 2022 Tocopheryl succinate (Tsuc) is a succinic acid ester of the well-known antioxidant α-tocopherol (T). Tsuc exhibits various biological activities, including tumor growth suppression via activation of cell signaling and prevention of lipid accumulation in ...
Misaki Yamasaki +7 more
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Lipid metabolism and storage in neuroglia: role in brain development and neurodegenerative diseases
Cell & Bioscience, 2022 The importance of neuroglia in maintaining normal brain function under physiological and pathological conditions has been supported by growing evidence in recent years.
Danying Yang +9 more
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Frontiers in Endocrinology, 2023 AimConfirm and compare the degree of associations of non-traditional lipid profiles and metabolic syndrome (MetS) in Chinese adolescents, determine the lipid parameter with better predictive potential, and investigate their discriminatory power on MetS ...
Zi-yi Chen +6 more
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Exploiting Bioprocessing Fluctuations to Elicit the Mechanistics of De Novo Lipogenesis in Yarrowia lipolytica. [PDF]
PLoS ONE, 2017 Despite substantial achievements in elucidating the metabolic pathways of lipogenesis, a mechanistic representation of lipid accumulation and degradation has not been fully attained to-date.
Andreas E Vasdekis +2 more
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Nonalcoholic Lipid Accumulation and Hepatocyte Malignant Transformation [PDF]
Journal of Clinical and Translational Hepatology, 2016 Worldwide incidence of hepatocellular carcinoma (HCC) is steadily increasing, highlighting its status as a public health concern, particularly due to its significant association with other comorbidities, such as diabetes. However, nonalcoholic fatty liver disease (NAFLD) has emerged as a primary risk factor, with its own prevalence increasing in recent
Gu, Juanjuan +5 more
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Journal of Lipid Research, 2017 Defective autophagy has been linked to lipotoxicity in several cellular models. We aimed to investigate autophagy in lipid-stimulated hepatoma (Huh7) cells and tested whether 4-phenyl butyric acid (4-PBA), a chemical chaperone, has a beneficial role in ...
Ashraf U. Nissar +7 more
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Frontiers in Pharmacology, 2017 Atherosclerosis (AS) is a lipid-driven disease in which macrophage foam cells play a critical role by increasing vascular lipid accumulation and contributing to plaque instability. Ginsenoside Rb1 (Rb1), the most abundant active component of ginseng, has
Lei Qiao +11 more
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