Results 61 to 70 of about 122,182 (249)

Electron Microscopic Observations of Lipid Antigens With Special Reference to the Wassermann Antigen [PDF]

Japanese Journal of Microbiology, 1974
ABSTRACTThe Wassermann antigen is a lipid micelle, and the essential component of the hapten is cardiolipin. It requires the addition of lecithin and cholesterol as auxiliary lipids. We conducted a study on the role of auxiliary lipids in the formation of the micelle structure using negative staining and observing with the electron microscope.
openaire   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Preparing Adjuvanted Nanoliposomes for Applications Toward Recombinant Influenza Vaccine Development

Bio-Protocol
Nanoparticle vaccines can provide advantages over traditional vaccine methodologies, including adjuvant delivery to enhance the effectiveness of recombinant antigens.
Zachary Sia, Wei-Chiao Huang, Matthew Willadsen, Hilliard Kutscher, Jonathan Lovell, Bruce Davidson   +5 more
doaj   +1 more source

Mycoketide: A CD1c-Presented Antigen with Important Implications in Mycobacterial Infection

Clinical and Developmental Immunology, 2012
Mycobacterium tuberculosis and related mycobacteria species are unique in that the acid-fast bacilli possess a highly lipid-rich cell wall that not simply confers resistance to treatment with acid alcohol, but also controls their survival and virulence ...
Isamu Matsunaga, Masahiko Sugita
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Nitration of GlcCer and Related Complex Lipids Enhances CD1d Binding Affinity and Modulates Immune Responses via Lipid Antigen Presentation to Natural Killer T Cells

ChemistryEurope
Nitration of unsaturated lipids occurs through the action of the signaling molecule nitric oxide (NO) and related reactive nitrogen species. Derivatives of the most abundant glycolipid, β‐GlcCer, containing nitro‐unsaturated fatty acids are synthesized ...
Kodai Sueyoshi, Nanako Kawate‐Horiuchi, Kazunari Ueki, Risa Nozawa, Takanori Matsumaru, Yukari Fujimoto   +5 more
doaj   +1 more source

CD1-restricted T cells: are unconventional allies the key to future TB vaccines?

Frontiers in Immunology
CD1-restricted T cells constitute an unconventional arm of immunity that recognises lipid antigens, a feature particularly pertinent to Mycobacterium tuberculosis (Mtb), a pathogen with a lipid-rich cell wall.
Matthew Milton, Salah Mansour, Salah Mansour   +2 more
doaj   +1 more source

Characteristics and Outcomes of Male Participants in a Multicenter Longitudinal Australian Study Cohort

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods This was a retrospective observational study using data from the Australian Scleroderma Cohort Study.
Emily Lin, Dylan Hansen, Laura Ross, Gene‐Siew Ngian, Susanna Proudman, Gabor Major, Maryam Tabesh, Mandana Nikpour, Jennifer Walker, Lauren Host, Nava Ferdowsi, Alannah Quinlivan, Wendy Stevens, Joanne Sahhar, Diane Apostolopoulos   +14 more
wiley   +1 more source

Systematic review on antigens for serodiagnosis of visceral leishmaniasis, with a focus on East Africa.

PLoS Neglected Tropical Diseases, 2019
BackgroundAccurate and accessible diagnosis is key for the control of visceral leishmaniasis (VL). Yet, current diagnostic tests for VL have severe limitations: they are invasive or not suitable as point of care (POC) test or their performance is ...
Vera Kühne, Zahra Rezaei, Paul Pitzinger, Philippe Büscher   +3 more
doaj   +1 more source