Results 41 to 50 of about 118,445 (283)
Frontiers in Immunology, 2018 Mycolic acid (MA), a major lipid component of Mycobacterium tuberculosis (Mtb) cell wall, can be presented by the non-polymorphic antigen presenting molecule CD1b to T cells isolated from Mtb-infected individuals.
Shaobin Shang +11 more
doaj +1 more source
Preparing Adjuvanted Nanoliposomes for Applications Toward Recombinant Influenza Vaccine Development. [PDF]
Bio ProtocNanoparticle vaccines can provide advantages over traditional vaccine methodologies, including adjuvant delivery to enhance the effectiveness of recombinant antigens.
Sia ZR +5 more
europepmc +2 more sources
CD1d-lipid antigen recognition by the γδ TCR [PDF]
Nature Immunology, 2013 The T lymphocytes repertoire is divided into two major lineages, αβ and γδ T cells, which are defined by their T cell receptor (TCR) gene-segment usage. To date, the key discoveries on human CD1d restricted T cells have focussed on the type I Natural Killer T cells (NKT) subset that express an invariant TCR α chain (Vα24Jα18) which pairs with a β chain
Uldrich, AP +10 more
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Harnessing the Power of Invariant Natural Killer T Cells in Cancer Immunotherapy
Frontiers in Immunology, 2017 Invariant natural killer T (iNKT) cells are a distinct subset of innate-like lymphocytes bearing an invariant T-cell receptor, through which they recognize lipid antigens presented by monomorphic CD1d molecules. Upon activation, iNKT cells are capable of
Melissa Bedard +2 more
doaj +1 more source
Immunoreactivity of nerve lipid antigens in leprosy
Journal of Clinical Laboratory Analysis, 1991 AbstractNeural lipid antigens, namely, galactocerebroside and ganglioside, have been implicated in demyelinating diseases. We were interested in finding the role of these antigens in leprosy neuritis. The humoral immune response to these lipid antigens was quantitated by enzyme‐linked immunosorbent assay in sera from 91 leprosy patients and 18 normal ...
N, Vemuri, R, Mukherjee
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Dual delivery of antigens shows promise
eLife, 2023 The simultaneous delivery of protein and lipid antigens via nanoparticles may help efforts to develop a new vaccine for tuberculosis.
Jose L Luque-García +1 more
doaj +1 more source
An improved preparation of bovine brain proteolipid
Journal of Lipid Research, 1967 An improved preparation of proteolipid from bovine brain white matter is described. The product obtained by repeated acetone precipitation is completely soluble in chloroform-methanol and has a fairly constant composition: 35% protein, 40 ...
Roberto Cavanna, Maurice M. Rapport
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The Conventional Nature of Non-MHC-Restricted T Cells
Frontiers in Immunology, 2018 The definition “unconventional T cells” identifies T lymphocytes that recognize non-peptide antigens presented by monomorphic antigen-presenting molecules.
Marco Lepore +2 more
doaj +1 more source
Role of natural killer T lymphocytes during helminthic infection
Parasite, 2008 Natural killer (NK)T cells are innate lymphocytes that release important amount of immunoregulatory cytokines (IFN-γ and/or IL-4) shortly after T cell receptor engagement by (glyco)lipid antigens presented by the CD1d molecules.
Faveeuw C., Mallevaey T., Trottein F.
doaj +1 more source
Editing of CD1d-Bound Lipid Antigens by Endosomal Lipid Transfer Proteins [PDF]
Science, 2004 It is now established that CD1 molecules present lipid antigens to T cells, although it is not clear how the exchange of lipids between membrane compartments and the CD1 binding groove is assisted. We report that mice deficient in prosaposin, the precursor to a family of endosomal lipid transfer proteins (LTP), exhibit specific defects in CD1d-mediated
Dapeng, Zhou +12 more
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