Results 21 to 30 of about 199,961 (298)

Anomeric O-Functionalization of Carbohydrates for Chemical Conjugation to Vaccine Constructs. [PDF]

open access: yes, 2018
Carbohydrates mediate a wide range of biological interactions, and understanding these processes benefits the development of new therapeutics. Isolating sufficient quantities of glycoconjugates from biological samples remains a significant challenge ...
Gervay-Hague, Jacquelyn   +2 more
core   +1 more source

Structure analysis of biologically important prokaryotic glycopolymers [PDF]

open access: yes, 2013
Of the many post-translational modifications organisms can undertake, glycosylation is the most prevalent and the most diverse. The research in this thesis focuses on the structural characterisation of glycosylation in two classes of glycopolymer (
Ventura, Valeria Victoria   +1 more
core   +1 more source

Vaccine approaches for antigen capture by liposomes

open access: yesExpert Review of Vaccines, 2023
Introduction Liposomes have been used as carriers for vaccine adjuvants and antigens due to their inherent biocompatibility and versatility as delivery vehicles.
Shiqi Zhou, Yuan Luo, Jonathan Lovell
doaj   +1 more source

An overview about erythrocyte membrane [PDF]

open access: yes, 2010
© 2010 – IOS Press and the authors. All rights reservedIn the sixties and seventies, erythrocytes or red blood cells (RBCs) were extensively studied. Much has been learnt particularly concerning their metabolism and gas transporter function. In the past
Oliveira, Sofia de, Saldanha, Carlota
core   +1 more source

Induction of Mycobacterium Tuberculosis Lipid-Specific T Cell Responses by Pulmonary Delivery of Mycolic Acid-Loaded Polymeric Micellar Nanocarriers

open access: yesFrontiers in Immunology, 2018
Mycolic acid (MA), a major lipid component of Mycobacterium tuberculosis (Mtb) cell wall, can be presented by the non-polymorphic antigen presenting molecule CD1b to T cells isolated from Mtb-infected individuals.
Shaobin Shang   +11 more
doaj   +1 more source

Presentation of Lipid Antigens by CD1 Glycoproteins [PDF]

open access: yesCurrent Pharmaceutical Design, 2009
CD1 molecules are a family of non-polymorphic, class I antigen-presenting glycoproteins, which bind and present amphiphilic lipid antigens for recognition to T cells. Two groups of CD1 molecules are involved in presentation of self and foreign lipid antigens: group 1 (CD1a, CD1b and CD1c) and group 2 (CD1d). Crystal structures of CD1a, CD1b and CD1d in
André, Schiefner, Ian A, Wilson
openaire   +2 more sources

Immune evasion of the CD1d/NKT cell axis [PDF]

open access: yes, 2018
Many reviews on the CD1d/NKT cell axis focus on the ability of CD1d-restricted NKT cells to serve as effector cells in a variety of disorders, be they infectious diseases, cancer or autoimmunity.
Brutkiewicz, Randy R.   +2 more
core   +1 more source

Harnessing the Power of Invariant Natural Killer T Cells in Cancer Immunotherapy

open access: yesFrontiers in Immunology, 2017
Invariant natural killer T (iNKT) cells are a distinct subset of innate-like lymphocytes bearing an invariant T-cell receptor, through which they recognize lipid antigens presented by monomorphic CD1d molecules. Upon activation, iNKT cells are capable of
Melissa Bedard   +2 more
doaj   +1 more source

Anti-ganglioside antibodies in patients with Zika virus infection-associated Guillain-Barré Syndrome in Brazil. [PDF]

open access: yes, 2019
Zika virus infection is associated with the development of Guillain-Barré syndrome (GBS), a neurological autoimmune disorder caused by immune recognition of gangliosides and other components at nerve membranes.
Alcantara, Luiz Carlos Junior   +7 more
core   +1 more source

Diversification of CD1 molecules shapes lipid antigen selectivity [PDF]

open access: yesMolecular Biology and Evolution, 2020
AbstractMolecular studies of host-pathogen evolution have largely focused on the consequences of variation at protein-protein interaction surfaces. The potential for other microbe-associated macromolecules to promote arms race dynamics with host factors remains unclear.
Nicole M. Paterson   +2 more
openaire   +3 more sources

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