Results 21 to 30 of about 229,223 (348)

Effect of gold nanoparticle on structure and fluidity of lipid membrane. [PDF]

open access: yesPLoS ONE, 2014
This paper deals with the effect of different size gold nanoparticles on the fluidity of lipid membrane at different regions of the bilayer. To investigate this, we have considered significantly large bilayer leaflets and incorporated only one ...
Anil R Mhashal, Sudip Roy
doaj   +1 more source

Combining Auxin-Induced Degradation and RNAi Screening Identifies Novel Genes Involved in Lipid Bilayer Stress Sensing in Caenorhabditis elegans

open access: yesG3: Genes, Genomes, Genetics, 2020
Alteration of the lipid composition of biological membranes interferes with their function and can cause tissue damage by triggering apoptosis. Upon lipid bilayer stress, the endoplasmic reticulum mounts a stress response similar to the unfolded protein ...
Richard Venz   +3 more
doaj   +1 more source

Puncturing lipid membranes: onset of pore formation and the role of hydrogen bonding in the presence of flavonoids

open access: yesJournal of Lipid Research, 2023
Products of lipid peroxidation induce detrimental structural changes in cell membranes, such as the formation of water pores, which occur in the presence of lipids with partially oxidized chains.
Anja Sadžak   +6 more
doaj   +1 more source

Simulations of Asymmetric Membranes Illustrate Cooperative Leaflet Coupling and Lipid Adaptability

open access: yesFrontiers in Cell and Developmental Biology, 2020
Biological membranes are composed of lipid bilayers that are often asymmetric with regards to the lipid composition and/or aqueous solvent they separate. Studying lipid asymmetry both experimentally and computationally is challenging.
Madison Blumer   +11 more
doaj   +1 more source

Biomimetic Cationic Nanoparticles Based on Silica: Optimizing Bilayer Deposition from Lipid Films

open access: yesBiomimetics, 2017
The optimization of bilayer coverage on particles is important for a variety of biomedical applications, such as drug, vaccine, and genetic material delivery.
Rodrigo T. Ribeiro   +2 more
doaj   +1 more source

Active site geometry stabilization of a presenilin homolog by the lipid bilayer promotes intramembrane proteolysis

open access: yeseLife, 2022
Cleavage of membrane proteins in the lipid bilayer by intramembrane proteases is crucial for health and disease. Although different lipid environments can potently modulate their activity, how this is linked to their structural dynamics is unclear. Here,
Lukas P Feilen   +5 more
doaj   +1 more source

Synthetic Analogues of the Snail Toxin 6-Bromo-2-mercaptotryptamine Dimer (BrMT) Reveal That Lipid Bilayer Perturbation Does Not Underlie Its Modulation of Voltage-Gated Potassium Channels [PDF]

open access: yes, 2018
Drugs do not act solely by canonical ligand–receptor binding interactions. Amphiphilic drugs partition into membranes, thereby perturbing bulk lipid bilayer properties and possibly altering the function of membrane proteins.
Aldrich, Richard W.   +12 more
core   +2 more sources

Functional tethered lipid bilayers

open access: yesReviews in Molecular Biotechnology, 2000
Our strategy to provide the structural basis for the build-up of functional tethered membranes focuses on three approaches: the first one is based on the pre-organization of a monomolecular layer of a lipopolymer at the water/air interface which is then transferred to a solid support.
Knoll, W.   +8 more
openaire   +3 more sources

Structure of lipid bilayers [PDF]

open access: yesBiochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, 2000
The quantitative experimental uncertainty in the structure of fully hydrated, biologically relevant, fluid (L(alpha)) phase lipid bilayers has been too large to provide a firm base for applications or for comparison with simulations. Many structural methods are reviewed including modern liquid crystallography of lipid bilayers that deals with the fully
J F, Nagle, S, Tristram-Nagle
openaire   +2 more sources

Lipid Polymorphism of the Subchloroplast—Granum and Stroma Thylakoid Membrane—Particles. I. 31P-NMR Spectroscopy

open access: yesCells, 2021
Build-up of the energized state of thylakoid membranes and the synthesis of ATP are warranted by organizing their bulk lipids into a bilayer. However, the major lipid species of these membranes, monogalactosyldiacylglycerol, is a non-bilayer lipid.
Ondřej Dlouhý   +7 more
doaj   +1 more source

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