Results 21 to 30 of about 1,320,816 (375)
Biophysica, 2023 Understanding the membrane interactions of the N-terminal 17 residues of the huntingtin protein (HttN) is essential for unraveling its role in cellular processes and its impact on huntingtin misfolding. In this study, we used atomic force microscopy (AFM)
Yasith Indigahawela Gamage, Jianjun Pan
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Current Opinion in Structural Biology, 2000 Fluctuations, inherent in flexible and biologically relevant lipid bilayers, make quantitative structure determination challenging. Shortcomings in older methods of structure determination have been realized and new methodologies have been introduced that take fluctuations into account.
John F. Nagle, Stephanie Tristram-Nagle
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DNA-nanostructure-templated assembly of planar and curved lipid-bilayer membranes
Frontiers in Chemistry, 2023 Lipid-bilayer nanodiscs and liposomes have been developed to stabilize membrane proteins in order to study their structures and functions. Nanodiscs are detergent-free, water-soluble, and size-controlled planar phospholipid-bilayer platforms.
Mostafa A. Elbahnasawy, Mahmoud L. Nasr
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Correlated diffusion in lipid bilayers [PDF]
Proceedings of the National Academy of Sciences, 2021 SignificanceDynamic processes on membrane surfaces are essential for biological function. Traditionally, quantitative measurements of lipid/protein motion have been interpreted in the framework of membrane hydrodynamics. However, some recent single-molecule tracking studies have proven difficult to interpret via hydrodynamic arguments.
Rafael L. Schoch +2 more
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Glycophorin in Lipid Bilayers [PDF]
Proceedings of the National Academy of Sciences, 1974 Glycophorin, the major glycoprotein of human erythrocytes, has been isolated and reincorporated into lipid vesicles. Freeze-fracture electron microscopy shows the reincorporated glycophorin to occur as small particles in vesicle fracture faces while the etch faces are smooth.
Chris M. Grant, Harden M. McConnell
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Volumetric stability of lipid bilayers [PDF]
Physical Chemistry Chemical Physics, 2012 In agreement with recent reports, a commercial densimeter has yielded a gradual decrease in lipid molecular volume of DPPC multilamellar vesicle dispersions in the gel phase upon repeated thermal cycling between 10 °C and 50 °C. The considerable size of this decrease would have significant implications for the physical chemistry of biomembranes.
Kelsey M. Hallinen +2 more
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Alcohol Interactions with Lipid Bilayers [PDF]
Molecules, 2017 We investigate the structural changes to lipid membrane that ensue from the addition of aliphatic alcohols with various alkyl tail lengths. Small angle neutron diffraction from flat lipid bilayers that are hydrated through water vapor has been employed to eliminate possible artefacts of the membrane curvature and the alcohol’s membrane-water ...
Tomáš Kondela +7 more
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Effect of gold nanoparticle on structure and fluidity of lipid membrane. [PDF]
PLoS ONE, 2014 This paper deals with the effect of different size gold nanoparticles on the fluidity of lipid membrane at different regions of the bilayer. To investigate this, we have considered significantly large bilayer leaflets and incorporated only one ...
Anil R Mhashal, Sudip Roy
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Composition Fluctuations in Lipid Bilayers [PDF]
Biophysical Journal, 2016 AbstractLipid bilayers constitute the basis of biological membranes. Understanding lipid mixing and phase behavior can provide important insights into membrane lateral organization (the “raft” hypothesis). Here we investigate model lipid bilayers below and above their miscibility transition temperatures.
Baoukina, Svetlana +2 more
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G3: Genes, Genomes, Genetics, 2020 Alteration of the lipid composition of biological membranes interferes with their function and can cause tissue damage by triggering apoptosis. Upon lipid bilayer stress, the endoplasmic reticulum mounts a stress response similar to the unfolded protein ...
Richard Venz +3 more
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