Results 21 to 30 of about 199,281 (229)
Membrane-protein interactions in mechanosensitive channels [PDF]
, 2004 In this paper, we examine the mechanical role of the lipid bilayer in ion channel conformation and function with specific reference to the case of the mechanosensitive channel of large conductance (MscL).
Bass +55 more
core +3 more sources
Cell-free protein expression systems in microdroplets: stabilization of interdroplet bilayers
, 2013 Cell-free protein expression with bacterial lysates has been demonstrated to produce soluble proteins in microdroplets. However, droplet assays with expressed membrane proteins require the presence of a lipid bilayer.
Hywel Morgan +3 more
core +1 more source
Energy transfer in lipid bilayers
Biophysical Journal, 1979 The quenching of fluorescence due to energy transfer between a dilute, random array of donor and acceptor chromophores in lipid bilayer was measured and compared to theoretical expressions developed to predict the decrease in emission intensity under these circumstances. The observed intensity was found to be the same function of quencher concentration
T.E. Thompson, T.N. Estep
openaire +3 more sources
Formation of unilamellar dipalmitoylphosphatidylcholine vesicles promoted by Ca2+ ions: A small-angle neutron scattering study [PDF]
, 2007 Dipalmitoylphosphatidylcholine (DPPC) was hydrated in 0.2-60 mM solution of CaCl 2 in heavy water and thoroughly homogenized by freezing-thawing process.
Almásy, László +3 more
core +1 more source
Water chains in lipid bilayers [PDF]
Biophysical Journal, 1996 tamic acid 204 is the terminal proton release group at the extracellular surface of bacteriorhodopsin. J. Biol. Chem. 270:27122-27126. Govindjee, R., S. Misra, S. P. Balashov, T. G. Ebrey, R. K. Crouch, and D. R. Menick. 1996. Arginine-82 regulates the pKa of the group responsible for the light-driven proton release in bacteriorhodopsin. Biophys. J. 71:
openaire +2 more sources
Microcavity supported lipid membranes: versatile platforms for building asymmetric lipid bilayers and for protein recognition [PDF]
, 2019 Microcavity supported lipid bilayers (MSLB) are contact-free membranes suspended across aqueousfilled pores that maintain the lipid bilayer in a highly fluidic state and free from frictional interactions with substrate.
Berselli, Guilherme +4 more
core +1 more source
Characterization of the transverse relaxation rates in lipid bilayers [PDF]
, 1990 The 2H NMR transverse relaxation rates of a deuterated phospholipid bilayer reflect slow motions in the bilayer membrane. A study of dimyristoyl lecithin specifically deuterated at several positions of the hydrocarbon chains indicates that these motions ...
Chan, Sunney I. +2 more
core
Native silica nanoparticles are powerful membrane disruptors [PDF]
, 2015 Silica nanoparticles are under development for intracellular drug delivery applications but can also have cytotoxic effects including cell membrane damage.
Alkhammash, Hend I. +3 more
core +1 more source
Structure determination of lipid bilayers
Biophysical Journal, 1978 A method of determining the phases of X-ray reflections from oriented model membrane systems at low resolution is described. The method involves deconvolution and requires that d less than or equal to 2v where v is the width of the head group region within the bilayer and d is the thickness of the bilayer.
R.S. Kharf, C.R. Worthington
openaire +3 more sources
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source