Results 1 to 10 of about 38,606 (200)
A Model of Lipid Monolayer–Bilayer Fusion of Lipid Droplets and Peroxisomes [PDF]
Membranes, 2022 Lipid droplets are unique organelles that store neutral lipids encapsulated by the lipid monolayer. In some processes of cellular metabolism, lipid droplets interact with peroxisomes resulting in the fusion of their envelopes and the formation of ...
Maksim A. Kalutsky +2 more
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Vesicle fusion with bilayer lipid membrane controlled by electrostatic interaction
Biochemistry and Biophysics Reports, 2017 The fusion of proteoliposomes is a promising approach for incorporating membrane proteins in artificial lipid membranes. In this study, we employed an electrostatic interaction between vesicles and supported bilayer lipid membranes (s-BLMs) to control ...
Azusa Oshima, Koji Sumitomo
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HIV Fusion Peptides Significantly Soften Lipid Bilayers [PDF]
Biophysical Journal, 2010 The fusion peptide (FP) of the human immunodeficiency virus (HIV) is found on N-terminus of the viral envelope glycoprotein gp41 and is believed to play an important role in the virus entry process. In order to understand the immediate effect of this peptide on the cell membrane we have studied the influence of the synthetic fusion peptide residue FP ...
Pavlo Shchelokovskyy +3 more
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Site-Specific DNA-Controlled Fusion of Single Lipid Vesicles to Supported Lipid Bilayers [PDF]
Biophysical Journal, 2010 AbstractWe investigate the Ca2+‐triggered fusion of lipid vesicles site‐selectively tethered to a DNA‐modified supported lipid bilayer array, with the DNA strands designed such that hybridization occurs in a zipperlike fashion. Prior to the addition of Ca2+, which is observed to induce docking and subsequent fusion (within 200 ms), the vesicles display
Lisa Simonsson +3 more
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A membrane fusion assay based on pore-spanning lipid bilayers [PDF]
Biophysical Journal, 2011 Pore-spanning planar membranes on highly ordered porous silicon substrates were shown to be well suited to monitor the calcium ion mediated fusion of large unilamellar vesicles by means of confocal laser scanning fluorescence microscopy and scanning ion conductance microscopy in real-time.
Ines Höfer, Claudia Steinem
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Influence of PLIN5 and lipid composition on lipid droplet contact sites with other organelles [PDF]
Biochemistry and Biophysics ReportsLipid droplets (LDs) maintain cellular lipid homeostasis through dynamic interactions with other organelles. Understanding how these contact sites form is crucial for uncovering the mechanisms of lipid exchange and signaling. In this study, we used an in
Mahsa Mohammadian +2 more
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Simulation of fusion-mediated nanoemulsion interactions with model lipid bilayers [PDF]
Soft Matter, 2012 Perfluorocarbon-based nanoemulsion particles have become promising platforms for the delivery of therapeutic and diagnostic agents to specific target cells in a non-invasive manner. A "contact-facilitated" delivery mechanism has been proposed wherein the emulsifying phospholipid monolayer on the nanoemulsion surface contacts and forms a lipid complex ...
Sun-Joo Lee +4 more
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Fusion of biomimetic stealth probes into lipid bilayer cores [PDF]
Proceedings of the National Academy of Sciences, 2010 Many biomaterials are designed to regulate the interactions between artificial and natural surfaces. However, when materials are inserted through the cell membrane itself the interface formed between the interior edge of the membrane and the material surface is not well understood and poorly controlled.
Benjamin D. Almquist, Nicholas A. Melosh
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Lipid Bilayer Vesicle Fusion: Intermediates Captured by High-Speed Microfluorescence Spectroscopy [PDF]
Biophysical Journal, 2003 The fusion of lipid bilayers can be visualized under the fluorescence microscope, but the process is very fast and requires special techniques for its study. It is reported here that vesicle fusion is susceptible to analysis by microspectrofluorometry and that for the first time, the entire fusion process has been captured.
Lei Guohua, Robert C. MacDonald
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Strain‐Promoted Cycloadditions in Lipid Bilayers Triggered by Liposome Fusion [PDF]
Angewandte Chemie International EditionAbstractDue to the variety of roles served by the cell membrane, its composition and structure are complex, making it difficult to study. Bioorthogonal reactions, such as the strain promoted azide‐alkyne cycloaddition (SPAAC), are powerful tools for exploring the function of biomolecules in their native environment but have been largely unexplored ...
Coline Jumeaux +11 more
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