Results 1 to 10 of about 107,533 (320)
A Model of Lipid Monolayer–Bilayer Fusion of Lipid Droplets and Peroxisomes
Membranes, 2022 Lipid droplets are unique organelles that store neutral lipids encapsulated by the lipid monolayer. In some processes of cellular metabolism, lipid droplets interact with peroxisomes resulting in the fusion of their envelopes and the formation of ...
Maksim A. Kalutsky +2 more
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Fast Membranes Hemifusion via Dewetting between Lipid Bilayers [PDF]
, 2014 The behavior of lipid bilayer is important to understand the functionality of cells like the trafficking of ions between cells. Standard procedures to explore the properties of lipid bilayer and hemifused states typically use either supported membranes or vesicles.
Fleury, Jean-Baptiste +2 more
arxiv +3 more sources
Efficient tunable generic model for fluid bilayer membranes [PDF]
, 2005 We present a model for the efficient simulation of generic bilayer membranes. Individual lipids are represented by one head- and two tail-beads. By means of simple pair potentials these robustly self-assemble to a fluid bilayer state over a wide range of parameters, without the need for an explicit solvent. The model shows the expected elastic behavior
Cooke, Ira R. +2 more
arxiv +4 more sources
Biophysica, 2023 The interaction of many peptides with lipid bilayer membranes strongly depends on the lipid composition. Here, a study of the impact of unsaturated lipid acyl chains on the interaction of a derivative of the HIV-1 fusion peptide with lipid bilayer ...
William T. Heller, Piotr A. Zolnierczuk
doaj +2 more sources
New mechanism of membrane fusion [PDF]
, 2001 We have carried out Monte Carlo simulation of the fusion of bilayers of single chain amphiphiles which show phase behavior similar to that of biological lipids. The fusion mechanism we observe is very different from the ``stalk'' hypothesis. Stalks do form on the first stage of fusion, but they do not grow radially to form a hemifused state.
K. Katsov +3 more
arxiv +3 more sources
Field theoretic study of bilayer membrane fusion: I. Hemifusion mechanism [PDF]
, 2003 Self-consistent field theory is used to determine structural and energetic properties of metastable intermediates and unstable transition states involved in the standard stalk mechanism of bilayer membrane fusion. A microscopic model of flexible amphiphilic chains dissolved in hydrophilic solvent is employed to describe these self-assembled structures.
Bates +47 more
arxiv +5 more sources
Vesicle fusion with bilayer lipid membrane controlled by electrostatic interaction
Biochemistry and Biophysics Reports, 2017 The fusion of proteoliposomes is a promising approach for incorporating membrane proteins in artificial lipid membranes. In this study, we employed an electrostatic interaction between vesicles and supported bilayer lipid membranes (s-BLMs) to control ...
Azusa Oshima, Koji Sumitomo
doaj +4 more sources
Formation of supported lipid bilayers of charged E. coli lipids on modified gold by vesicle fusion
MethodsX, 2017 We describe a simple way of fusing E. coli lipid vesicles onto a gold surface. Supported lipid bilayers on metal surfaces are interesting for several reasons: transducing a biological signal to an electric readout, using surface analytical tools such as ...
Ileana F. Márquez, Marisela Vélez
doaj +4 more sources
SMARTINI3 parametrization of multi-scale membrane models via unsupervised learning methods [PDF]
Scientific ReportsIn this study, we utilize genetic algorithms to develop a realistic implicit solvent ultra-coarse-grained (ultra-CG) membrane model comprising only three interaction sites.
Alireza Soleimani +1 more
doaj +2 more sources
Biophysica, 2023 Understanding the membrane interactions of the N-terminal 17 residues of the huntingtin protein (HttN) is essential for unraveling its role in cellular processes and its impact on huntingtin misfolding. In this study, we used atomic force microscopy (AFM)
Yasith Indigahawela Gamage, Jianjun Pan
doaj +1 more source