Results 21 to 30 of about 107,533 (320)
Fusion of biomimetic stealth probes into lipid bilayer cores [PDF]
Proceedings of the National Academy of Sciences, 2009 Many biomaterials are designed to regulate the interactions between artificial and natural surfaces. However, when materials are inserted through the cell membrane itself the interface formed between the interior edge of the membrane and the material surface is not well understood and poorly controlled.
Benjamin D. Almquist, Nicholas A. Melosh
openaire +6 more sources
Topological transitions in fluid lipid vesicles: activation energy and force fields [PDF]
Activation energy and force fields during topological transitions
of fluid lipid vesicles. Commun Phys 5, 283 (2022), 2022 Lipid bilayer membranes are the fundamental biological barriers that permit life. The bilayer dynamics largely participates in orchestrating cellular workings and is characterized by substantial stability together with extreme plasticity that allows controlled morphological/topological changes.
arxiv +1 more source
Effect of Dengue Fusion Peptide in Anionic Lipid Bilayers [PDF]
Biophysical Journal, 2015 Studies involving peptide-induced membrane fusion are extremely important to better understanding the mechanisms underlying virus entry in cells. Particularly, membrane fusion peptides are part of Dengue virus system serving as a gateway to the virus access into the cell. Here we study the interaction of the Dengue Flavivirus fusion peptide (FLAg) with
Karin A. Riske, Thaís F. Schmidt
openaire +2 more sources
Supported Lipid Bilayer Formation: Beyond Vesicle Fusion
Langmuir, 2020 Supported lipid bilayers (SLBs) are cell-membrane-mimicking platforms that can be formed on solid surfaces and integrated with a wide range of surface-sensitive measurement techniques. SLBs are useful for unravelling details of fundamental membrane biology and biophysics as well as for various medical, biotechnology, and environmental science ...
Joshua A. Jackman, Nam-Joon Cho
openaire +5 more sources
Atomic-resolution simulations predict a transition state for vesicle fusion defined by contact of a few lipid tails. [PDF]
PLoS Computational Biology, 2010 Membrane fusion is essential to both cellular vesicle trafficking and infection by enveloped viruses. While the fusion protein assemblies that catalyze fusion are readily identifiable, the specific activities of the proteins involved and nature of the ...
Peter M Kasson +2 more
doaj +1 more source
HIV Fusion Peptides Significantly Soften Lipid Bilayers [PDF]
Biophysical Journal, 2010 The fusion peptide (FP) of the human immunodeficiency virus (HIV) is found on N-terminus of the viral envelope glycoprotein gp41 and is believed to play an important role in the virus entry process. In order to understand the immediate effect of this peptide on the cell membrane we have studied the influence of the synthetic fusion peptide residue FP ...
Pavlo Shchelokovskyy +3 more
openaire +2 more sources
Biomimetic Models to Investigate Membrane Biophysics Affecting Lipid–Protein Interaction
Frontiers in Bioengineering and Biotechnology, 2020 Biological membranes are highly dynamic in their ability to orchestrate vital mechanisms including cellular protection, organelle compartmentalization, cellular biomechanics, nutrient transport, molecular/enzymatic recognition, and membrane fusion ...
Joe Sarkis, Joe Sarkis, Véronique Vié
doaj +1 more source
A New Mechanism of Model Membrane Fusion Determined from Monte Carlo Simulation [PDF]
, 2003 We have carried out extensive Monte Carlo simulations of the fusion of tense apposed bilayers formed by amphiphilic molecules within the framework of a coarse grained lattice model. The fusion pathway differs from the usual stalk mechanism.
Bonnafous +48 more
core +3 more sources
Membrane Fusion Assay Based on Pore-Spanning Lipid Bilayers [PDF]
Biophysical Journal, 2010 Pore-spanning planar membranes on highly ordered porous silicon substrates were shown to be well suited to monitor the calcium ion mediated fusion of large unilamellar vesicles by means of confocal laser scanning fluorescence microscopy and scanning ion conductance microscopy in real-time.
Höfer, Ines, Steinem, Claudia
openaire +6 more sources
A solid-state NMR study of changes in lipid phase induced by membrane-fusogenic LV-peptides [PDF]
, 2010 Membrane fusion requires restructuring of lipid bilayers mediated by fusogenic membrane proteins. Peptides that correspond to natural transmembrane sequences or that have been designed to mimic them, such as low-complexity “Leu-Val” (LV) peptide ...
Agrawal, Prashant +5 more
core +2 more sources