Results 51 to 60 of about 38,606 (200)

Untargeted Lipidomics of Vesicular Stomatitis Virus-Infected Cells and Viral Particles

open access: yesViruses, 2021
The viral lifecycle is critically dependent upon host lipids. Enveloped viral entry requires fusion between viral and cellular membranes. Once an infection has occurred, viruses may rely on host lipids for replication and egress.
Katherine E. Havranek   +3 more
doaj   +1 more source

Membrane-spanning lipids for an uncompromised monitoring of membrane fusion and intermembrane lipid transfer

open access: yesJournal of Lipid Research, 2015
A Förster resonance energy transfer-based fusion and transfer assay was developed to study, in model membranes, protein-mediated membrane fusion and intermembrane lipid transfer of fluorescent sphingolipid analogs.
Günter Schwarzmann   +2 more
doaj   +1 more source

Functions of SNAREs in intracellular membrane fusion and lipid bilayer mixing [PDF]

open access: yesJournal of Cell Science, 2005
Intracellular membrane fusion occurs with exquisite coordination and specificity. Each fusion event requires three basic components: Rab-GTPases organize the fusion site; SNARE proteins act during fusion; and N-ethylmaleimide-sensitive factor (NSF) plus its cofactor α-SNAP are required for recycling or activation of the fusion machinery.
Christian, Ungermann, Dieter, Langosch
openaire   +2 more sources

Membrane partitioning of anionic, ligand-coated nanoparticles is accompanied by ligand snorkeling, local disordering, and cholesterol depletion.

open access: yesPLoS Computational Biology, 2014
Intracellular uptake of nanoparticles (NPs) may induce phase transitions, restructuring, stretching, or even complete disruption of the cell membrane.
Paraskevi Gkeka   +3 more
doaj   +1 more source

Sensing-Applications of Surface-Based Single Vesicle Arrays

open access: yesSensors, 2010
A single lipid vesicle can be regarded as an autonomous ultra-miniaturised 3D biomimetic “scaffold” (Ø ≥ 13 nm) ideally suited for reconstitution and interrogation of biochemical processes. The enclosing lipid bilayer membrane of a vesicle can be applied
Sune M. Christensen, Dimitrios G. Stamou
doaj   +1 more source

Transmembrane Membrane Readers form a Novel Class of Proteins That Include Peripheral Phosphoinositide Recognition Domains and Viral Spikes

open access: yesMembranes, 2022
Membrane proteins are broadly classified as transmembrane (TM) or peripheral, with functions that pertain to only a single bilayer at a given time. Here, we explicate a class of proteins that contain both transmembrane and peripheral domains, which we ...
Michael Overduin   +4 more
doaj   +1 more source

Coiled-Coil Formation on Lipid Bilayers—Implications for Docking and Fusion Efficiency [PDF]

open access: yesBiophysical Journal, 2012
Coiled-coil formation of four different oligopeptides was characterized in solution, on hydrogels, and on membranes by employing circular dichroism spectroscopy, surface plasmon resonance spectroscopy, attenuated total reflection infrared spectroscopy, and ellipsometry.
Paehler, Gesa   +3 more
openaire   +3 more sources

A supramolecular system mimicking the infection process of an enveloped virus through membrane fusion

open access: yesScientific Reports, 2023
Membrane fusion is an essential step for the entry of enveloped viruses, such as human immunodeficiency virus and influenza virus, into the host cell, often triggered by the binding of membrane proteins on the viral envelope to host cell membrane ...
Hiroto Furukawa   +3 more
doaj   +1 more source

How Influenza Virus Uses Host Cell Pathways during Uncoating

open access: yesCells, 2021
Influenza is a zoonotic respiratory disease of major public health interest due to its pandemic potential, and a threat to animals and the human population.
Etori Aguiar Moreira   +2 more
doaj   +1 more source

Formation of supported lipid bilayers of charged E. coli lipids on modified gold by vesicle fusion

open access: yesMethodsX, 2017
We describe a simple way of fusing E. coli lipid vesicles onto a gold surface. Supported lipid bilayers on metal surfaces are interesting for several reasons: transducing a biological signal to an electric readout, using surface analytical tools such as ...
Ileana F. Márquez, Marisela Vélez
doaj   +1 more source

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