Results 51 to 60 of about 107,533 (320)
Mechanical properties of anionic asymmetric bilayers from atomistic simulations [PDF]
, 2021 Mechanotransduction, the biological response to mechanical stress, is often initiated by the activation of mechanosensitive (MS) proteins upon mechanically induced deformations of the cell membrane. A current challenge to fully understand this process is to predict how lipid bilayers deform upon application of mechanical stress.
arxiv +1 more source
The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers. [PDF]
, 2011 Encapsulation of drugs within nanocarriers that selectively target malignant cells promises to mitigate side effects of conventional chemotherapy and to enable delivery of the unique drug combinations needed for personalized medicine.
Ashley, Carlee E +20 more
core +2 more sources
Simulation of fusion-mediated nanoemulsion interactions with model lipid bilayers [PDF]
Soft Matter, 2012 Perfluorocarbon-based nanoemulsion particles have become promising platforms for the delivery of therapeutic and diagnostic agents to specific target cells in a non-invasive manner. A "contact-facilitated" delivery mechanism has been proposed wherein the emulsifying phospholipid monolayer on the nanoemulsion surface contacts and forms a lipid complex ...
Paul H. Schlesinger +4 more
openaire +3 more sources
Cell-inspired, massive electromodulation of interfacial energy dissipation [PDF]
arXiv, 2023 Transient electric fields across cell bilayer membranes can lead to electroporation, as well as to cell fusion, and have been extensively studied. We find that transmembrane electric fields similar to those in cells can lead to a massive, reversible modulation--by up to 200-fold--of the interfacial energy dissipation between surfaces sliding across the
arxiv
Field Theoretic Study of Bilayer Membrane Fusion: II. Mechanism of a Stalk-Hole Complex [PDF]
, 2005 We use self-consistent field theory to determine structural and energetic properties of intermediates and transition states involved in bilayer membrane fusion.
Blumenthal +42 more
core +3 more sources
Mechanisms of Membrane Curvature Generation in Membrane Traffic
Membranes, 2012 During the vesicular trafficking process, cellular membranes undergo dynamic morphological changes, in particular at the vesicle generation and fusion steps.
Hye-Won Shin +2 more
doaj +1 more source
Lipid bilayer degradation induced by SARS-CoV-2 spike protein as revealed by neutron reflectometry
Scientific Reports, 2021 SARS-CoV-2 spike proteins are responsible for the membrane fusion event, which allows the virus to enter the host cell and cause infection. This process starts with the binding of the spike extramembrane domain to the angiotensin-converting enzyme 2 ...
Alessandra Luchini +11 more
doaj +1 more source
Biomolecules, 2023 Mitochondria are highly dynamic organelles that constantly undergo fusion and fission events to maintain their shape, distribution and cellular function.
Anaïs Vlieghe +5 more
doaj +1 more source
Structure and Topology of the Influenza Virus Fusion Peptide in Lipid Bilayers [PDF]
Journal of Biological Chemistry, 1995 The secondary structure of a 20-amino acid length synthetic peptide corresponding to the N terminus of the second subunit of hemagglutinin (HA2) of influenza virus A/PR8/34 and its interaction with phospholipid bilayers are investigated using ESR, Fourier transform infrared (FTIR), and CD spectroscopy.
Lüneberg, J +4 more
openaire +3 more sources
Functions of SNAREs in intracellular membrane fusion and lipid bilayer mixing [PDF]
Journal of Cell Science, 2005 Intracellular membrane fusion occurs with exquisite coordination and specificity. Each fusion event requires three basic components: Rab-GTPases organize the fusion site; SNARE proteins act during fusion; and N-ethylmaleimide-sensitive factor (NSF) plus its cofactor α-SNAP are required for recycling or activation of the fusion machinery.
Christian Ungermann, Dieter Langosch
openaire +3 more sources