Results 81 to 90 of about 107,533 (320)
Defect formation of lytic peptides in lipid membranes and their influence on the thermodynamic properties of the pore environment [PDF]
, 2006 We present an experimental study of the pore formation processes of small amphipathic peptides in model phosphocholine lipid membranes. We used atomic force microscopy to characterize the spatial organization and structure of alamethicin- and melittin ...
Binnig +51 more
core +2 more sources
Cholesterol-Mediated Clustering of the HIV Fusion Protein gp41 in Lipid Bilayers
Journal of Molecular Biology, 2022 The envelope glycoprotein (Env) of the human immunodeficient virus (HIV-1) is known to cluster on the viral membrane surface to attach to target cells and cause membrane fusion for HIV-1 infection. However, the molecular structural mechanisms that drive Env clustering remain opaque.
Mei Hong +4 more
openaire +3 more sources
Advanced Biology, EarlyView.Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi +4 more
wiley +1 more source
Sensing-Applications of Surface-Based Single Vesicle Arrays
Sensors, 2010 A single lipid vesicle can be regarded as an autonomous ultra-miniaturised 3D biomimetic “scaffold” (Ø ≥ 13 nm) ideally suited for reconstitution and interrogation of biochemical processes. The enclosing lipid bilayer membrane of a vesicle can be applied
Sune M. Christensen, Dimitrios G. Stamou
doaj +1 more source
Membranes, 2022 Membrane proteins are broadly classified as transmembrane (TM) or peripheral, with functions that pertain to only a single bilayer at a given time. Here, we explicate a class of proteins that contain both transmembrane and peripheral domains, which we ...
Michael Overduin +4 more
doaj +1 more source
Structure and function of bacterial dynamin-like proteins [PDF]
, 2012 Membrane dynamics are essential for numerous cellular processes in eukaryotic and prokaryotic cells. In eukaryotic cells, membrane fusion and fission are often catalyzed by large GTPases of the dynamin protein family. These proteins couple GTP hydrolysis
Bramkamp, Marc
core +1 more source
Advanced Functional Materials, EarlyView.Mesenchymal stem cell‐derived nanoghosts (MSC‐NGs) mimic naturally secreted extracellular vesicles (MSC‐EVs) in structure and physicochemical properties but can be synthesized at more translatable yields. As osteogenic agents, MSC‐NGs demonstrate superior outcomes compared to MSC‐EVs.
Antoine Karoichan +4 more
wiley +1 more source
How Influenza Virus Uses Host Cell Pathways during Uncoating
Cells, 2021 Influenza is a zoonotic respiratory disease of major public health interest due to its pandemic potential, and a threat to animals and the human population.
Etori Aguiar Moreira +2 more
doaj +1 more source
Advanced Functional Materials, EarlyView.This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley +1 more source
Dual action of BPC194: a membrane active peptide killing bacterial cells. [PDF]
PLoS ONE, 2013 Membrane active peptides can perturb the lipid bilayer in several ways, such as poration and fusion of the target cell membrane, and thereby efficiently kill bacterial cells.
Gemma Moiset +5 more
doaj +1 more source