Results 11 to 20 of about 870,619 (302)
Lipid droplet analysis in caveolin-deficient adipocytes: alterations in surface phospholipid composition and maturation defects[S] [PDF]
Journal of Lipid Research, 2010 Caveolins form plasmalemnal invaginated caveolae. They also locate around intracellular lipid droplets but their role in this location remains unclear. By studying primary adipocytes that highly express caveolin-1, we characterized the impact of caveolin-
Cédric M. Blouin +12 more
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The Vacuole Lipid Droplet Contact Site vCLIP
ContactLipid droplets frequently form contact sites with the membrane of the vacuole, the lysosome-like organelle in yeast. These vacuole lipid droplet (vCLIP) contact sites respond strongly to metabolic cues: while only a subset of lipid droplets is bound to ...
Duy Trong Vien Diep, Maria Bohnert
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Triglyceride containing lipid droplets and lipid droplet-associated proteins
Current Opinion in Lipidology, 2008 Cytosolic lipid droplets are now recognized as dynamic organelles. This review summarizes our current understanding of the mechanisms involved in the formation of lipid droplets, the importance of lipid droplet-associated proteins and the link between lipid droplet accumulation and development of insulin resistance.Lipid droplets are formed as ...
Sven-Olof, Olofsson +6 more
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Pex3 promotes formation of peroxisome-peroxisome and peroxisome-lipid droplet contact sites [PDF]
Scientific ReportsPeroxisomes are ubiquitous organelles that mediate central metabolic functions, such as fatty acid β-oxidation, as well as diverse tissue- and organism-specific processes.
Lucía Amado +9 more
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TFAP2 transcription factors are regulators of lipid droplet biogenesis
eLife, 2018 How trafficking pathways and organelle abundance adapt in response to metabolic and physiological changes is still mysterious, although a few transcriptional regulators of organellar biogenesis have been identified in recent years.
Cameron C Scott +3 more
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Droplet size dependency and spatial heterogeneity of lipid oxidation in whey protein isolate-stabilized emulsions [PDF]
, 2023 Spatiotemporal assessment of lipid and protein oxidation is key for understanding quality deterioration in emulsified food products containing polyunsaturated fatty acids.
Karin, Schroën +7 more
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Lipid droplet metabolism [PDF]
Current Opinion in Clinical Nutrition and Metabolic Care, 2013 With the realization that lipid droplets are not merely inert fat storage organelles, but highly dynamic and actively involved in cellular lipid homeostasis, there has been an increased interest in lipid droplet biology. Recent studies have begun to unravel the roles that lipid dropletss play in cellular physiology and provide insights into the ...
Victor K, Khor +2 more
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The life of lipid droplets [PDF]
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2009 Lipid droplets are the least characterized of cellular organelles. Long considered simple lipid storage depots, these dynamic and remarkable organelles have recently been implicated in many biological processes, and we are only now beginning to gain insights into their fascinating lives in cells.
Walther, T., Farese, R.
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Pathophysiology of Lipid Droplets in Neuroglia [PDF]
Antioxidants, 2021 In recent years, increasing evidence regarding the functional importance of lipid droplets (LDs), cytoplasmic storage organelles in the central nervous system (CNS), has emerged. Although not abundantly present in the CNS under normal conditions in adulthood, LDs accumulate in the CNS during development and aging, as well as in some neurologic ...
Tina Smolič, Robert Zorec, Nina Vardjan
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Lipid Droplet Biogenesis [PDF]
Annual Review of Cell and Developmental Biology, 2017 Lipid droplets (LDs) are ubiquitous organelles that store neutral lipids for energy or membrane synthesis and act as hubs for metabolic processes. Cells generate LDs de novo, converting cells to emulsions with LDs constituting the dispersed oil phase in the aqueous cytoplasm. Here we review our current view of LD biogenesis.
Tobias C, Walther +2 more
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