Results 1 to 10 of about 133,206 (305)
Lipid-nanoparticle-induced vacuolization in microglia [PDF]
Communications BiologyLipid-containing vacuoles in microglia were discovered more than one hundred years ago in the brain of patients showing neurodegenerative processes.
Hubert H. Kerschbaum +5 more
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Machine learning techniques for lipid nanoparticle formulation [PDF]
Nano ConvergenceA significant amount of effort has been poured into optimizing the delivery system that is demanded by novel therapeutic modalities. Lipid nanoparticle presents as a solution to transfect cells safely and efficiently with nucleic acid-based therapeutics.
Hao Li, Yayi Zhao, Chenjie Xu
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Effect of gold nanoparticle on structure and fluidity of lipid membrane. [PDF]
PLoS ONE, 2014 This paper deals with the effect of different size gold nanoparticles on the fluidity of lipid membrane at different regions of the bilayer. To investigate this, we have considered significantly large bilayer leaflets and incorporated only one ...
Anil R Mhashal, Sudip Roy
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Molecular Therapy: Methods & Clinical Development, 2023 Crigler-Najjar syndrome is a rare disorder of bilirubin metabolism caused by uridine diphosphate glucuronosyl transferase 1A1 (UGT1A1) mutations characterized by hyperbilirubinemia and jaundice.
Jenny A. Greig +9 more
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A saposin-lipoprotein nanoparticle system for membrane proteins. [PDF]
, 2016 A limiting factor in membrane protein research is the ability to solubilize and stabilize such proteins. Detergents are used most often for solubilizing membrane proteins, but they are associated with protein instability and poor compatibility with ...
Armache, Jean-Paul +13 more
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Pharmaceuticals, 2023 In biomedical applications, nanomaterial-based delivery vehicles, such as lipid nanoparticles, have emerged as promising instruments for improving the solubility, stability, and encapsulation of various payloads.
Tetiana Korzun +7 more
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LIPID AND SILVER NANOPARTICLES GELS FORMULATION OF TEMPEH EXTRACT
Jurnal Farmasi Sains dan Komunitas, 2020 Tempeh extract is used in this study as an active ingredient in lipid nanoparticles and reductant in silver nanoparticles because tempeh is an authentic Indonesian food ingredient and is known to have the main content of isoflavones.
Felicia Satya Christania +2 more
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Solid Lipid Nanoparticles vs. Nanostructured Lipid Carriers: A Comparative Review
Pharmaceutics, 2023 Solid–lipid nanoparticles and nanostructured lipid carriers are delivery systems for the delivery of drugs and other bioactives used in diagnosis, therapy, and treatment procedures. These nanocarriers may enhance the solubility and permeability of drugs,
Cláudia Viegas +5 more
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Advances in Pancreatic Cancer Treatment by Nano-Based Drug Delivery Systems
Pharmaceutics, 2023 Pancreatic cancer represents one of the most lethal cancer types worldwide, with a 5-year survival rate of less than 5%. Due to the inability to diagnose it promptly and the lack of efficacy of existing treatments, research and development of innovative ...
Cláudia Viegas +6 more
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Molecular Therapy: Nucleic Acids, 2022 Arginase deficiency is associated with prominent neuromotor features, including spastic diplegia, clonus, and hyperreflexia; intellectual disability and progressive neurological decline are other signs.
Suhail Khoja +14 more
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