Results 31 to 40 of about 88,630 (306)
Lipid-Based Nanocarriers for Ophthalmic Administration: Towards Experimental Design Implementation
Pharmaceutics, 2021 Nanotherapeutics based on biocompatible lipid matrices allow for enhanced solubility of poorly soluble compounds in the treatment of ophthalmic diseases, overcoming the anatomical and physiological barriers present in the eye, which, despite the ease of ...
Felipe M. González-Fernández +4 more
doaj +1 more source
Lipid Nanoparticles for Gene Delivery [PDF]
, 2014 Nonviral vectors which offer a safer and versatile alternative to viral vectors have been developed to overcome problems caused by viral carriers. However, their transfection efficacy or level of expression is substantially lower than viral vectors. Among various nonviral gene vectors, lipid nanoparticles are an ideal platform for the incorporation of ...
Yi, Zhao, Leaf, Huang
openaire +2 more sources
Microfluidic fabrication of vesicles with hybrid lipid/nanoparticle bilayer membranes
, 2019 Hybrid lipid/nanoparticle membranes are suitable model systems both to study the complex interactions between nanoparticles and biological membranes, and to demonstrate technological concepts in cellular sensing and drug delivery.
Andrés Guerrero-Martinez +15 more
core +2 more sources
A novel mechanism for the loss of mRNA activity in lipid nanoparticle delivery systems
Nature Communications, 2021 Lipid nanoparticle delivery of mRNA vaccines has become of particular importance, however, mRNA stability is a major concern. Here, the authors report on a study of lipid impurity mRNA interactions using reverse phase ion pair HPLC to identify reactions ...
Meredith Packer +4 more
doaj +1 more source
Nutrition analysis by nanoparticle-assisted laser desorption/ionisation mass spectrometry [PDF]
, 2010 We analysed the bioactive compounds in Panax ginseng C.A. Meyer by using nanoparticle-assisted laser desorption/ionisation (nano-PALDI) mass spectrometry (MS). To this end, we prepared manganese oxide nanoparticles (d = 5.4 nm) and developed a nano-PALDI
Osaka, Issey +5 more
core +1 more source
Artificial Cells, Nanomedicine, and Biotechnology, 2021 The management of bacterial infections, especially trains of methicillin-resistant Staphylococcus aureus observe in health care settings, has markedly improved with the introduction of established drugs but using newer nano-based formulations. This study
Edwin Coleridge Stephen Naidu +5 more
doaj +1 more source
Lipid Nanoparticles for Ocular Gene Delivery
Journal of Functional Biomaterials, 2015 Lipids contain hydrocarbons and are the building blocks of cells. Lipids can naturally form themselves into nano-films and nano-structures, micelles, reverse micelles, and liposomes.
Yuhong Wang +2 more
doaj +1 more source
Lipid-based nanoparticles for treatment of cancer
Heliyon, 2022 Investigators were continuously creating novel nanotechnologies to address unmet requirements throughout the administration of therapeutic medicines & imaging agents for cancer treatment & diagnostics, appropriately. LNPs(Lipid nanoparticles) are legitimate particulates (approx.
Sumit Sheoran +4 more
openaire +3 more sources
Development and evaluation of lipid nanoparticles for camptothecin delivery: a comparison of solid lipid nanoparticles, nanostructured lipid carriers, and lipid emulsion [PDF]
Acta Pharmacologica Sinica, 2008 Camptothecin is an anticancer drug that acts against a broad spectrum of tumors. The clinical application of camptothecin is limited by its insolubility, instability, and toxicity problems. The aim of this study was to develop and characterize lipid nanoparticles with different lipid cores which can circumvent these problems.Lipid nanoparticles made of
Zih-rou, Huang +3 more
openaire +2 more sources
Remotely Controlled Diffusion from Magnetic Liposome Microgels [PDF]
, 2013 The reversible, temperature-dependent change in the permeability of a phospholipid bilayer has been used for controlling the diffusion rate of encapsulated molecular payload from liposomes.
Jiří Dohnal +9 more
core +1 more source