Results 11 to 20 of about 88,630 (306)
Lipid Nanoparticle-Mediated Liver-Specific Gene Therapy for Hemophilia B
PharmaceuticsBackground/Objectives: Hemophilia B is a hereditary bleeding disorder due to the production of liver malfunctional factor IX (FIX). Gene therapy with viral vectors offers a cure.
Brijesh Lohchania +5 more
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International Journal of Nanomedicine, 2011 Shuyu Xie1,*, Baoliang Pan1,*, Baoxin Shi2, Zhuangzhi Zhang2, Xu Zhang2, Ming Wang1, Wenzhong Zhou11Department of Preventive Veterinary Medicine, College of Veterinary Medicine, China Agricultural University, Beijing, People’s Republic of China;
Xie S +6 more
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Lipid nanoparticles for mRNA delivery [PDF]
Nature Reviews Materials, 2021 Messenger RNA (mRNA) has emerged as a new category of therapeutic agent to prevent and treat various diseases. To function in vivo, mRNA requires safe, effective and stable delivery systems that protect the nucleic acid from degradation and that allow cellular uptake and mRNA release.
Xucheng Hou +3 more
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Nanoparticle-Engendered Rupture of Lipid Membranes
, 2018 Tension-induced rupture of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) lipid membranes with encapsulated hydrophobic nanoparticles is elucidated using dissipative particle dynamics simulations.
Christopher Tsovko (5625479) +3 more
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From lipids to lipid nanoparticles to mRNA vaccines [PDF]
Nature Reviews Materials, 2021 Lipid nanoparticles are essential to mRNA vaccines. The groundwork for lipid-based drug delivery systems was laid more than 40 years ago in the lab of Pieter Cullis, Professor at the University of British Columbia. Nature Reviews Materials talks to Pieter Cullis about the history and future of lipid nanoparticle-nucleic acid drugs.
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Pharmaceuticals, 2023 In biomedical applications, nanomaterial-based delivery vehicles, such as lipid nanoparticles, have emerged as promising instruments for improving the solubility, stability, and encapsulation of various payloads.
Tetiana Korzun +7 more
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LIPID AND SILVER NANOPARTICLES GELS FORMULATION OF TEMPEH EXTRACT
Jurnal Farmasi Sains dan Komunitas, 2020 Tempeh extract is used in this study as an active ingredient in lipid nanoparticles and reductant in silver nanoparticles because tempeh is an authentic Indonesian food ingredient and is known to have the main content of isoflavones.
Felicia Satya Christania +2 more
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Solid Lipid Nanoparticles vs. Nanostructured Lipid Carriers: A Comparative Review
Pharmaceutics, 2023 Solid–lipid nanoparticles and nanostructured lipid carriers are delivery systems for the delivery of drugs and other bioactives used in diagnosis, therapy, and treatment procedures. These nanocarriers may enhance the solubility and permeability of drugs,
Cláudia Viegas +5 more
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Challenges in the Physical Characterization of Lipid Nanoparticles [PDF]
Pharmaceutics, 2021 Nano-sized drug transporters have become an efficient approach with considerable commercial values. Nanomedicine is not only limited to drug delivery by means of different administration routes, such as intravenous, oral, transdermal, nasal, pulmonary, and more, but also has applications in a multitude of areas, such as a vaccine, antibacterial ...
Supandeep Singh Hallan +3 more
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Advances in Pancreatic Cancer Treatment by Nano-Based Drug Delivery Systems
Pharmaceutics, 2023 Pancreatic cancer represents one of the most lethal cancer types worldwide, with a 5-year survival rate of less than 5%. Due to the inability to diagnose it promptly and the lack of efficacy of existing treatments, research and development of innovative ...
Cláudia Viegas +6 more
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