Results 291 to 300 of about 2,353,041 (346)

Optimal murine CD4⁺ T cell priming by mRNA-lipid nanoparticle vaccines requires endogenous antigen processing. [PDF]

Nat Commun
Rood JE, Yoon SK, Heard MK, Carro SD, Hedgepeth EJ, O'Mara ME, Hogan MJ, Le N, Muramatsu H, Lam K, Schreiner P, Kasden C, Stedman HH, Langlois RA, Heyes J, Pardi N, Eisenlohr LC.   +16 more
europepmc   +1 more source

A lipid nanoparticle encapsulated CPA-CTD mRNA vaccine provides protection against <i>Clostridium perfringens</i>-driven diseases. [PDF]

Front Immunol
Jia Q, Xiang H, Le T, Wang J, Chang J, Wang F, Sun C, Tai W, Jiang Z, Yin X.   +9 more
europepmc   +1 more source

A general genome editing strategy using CRISPR lipid nanoparticle spherical nucleic acids. [PDF]

Proc Natl Acad Sci U S A
Han Z, Huang C, Luo T, Mirkin CA.
europepmc   +1 more source

Correction: Wang et al. Impact of Protein Coronas on Lipid Nanoparticle Uptake and Endocytic Pathways in Cells. <i>Molecules</i> 2024, <i>29</i>, 4818. [PDF]

Molecules
Wang R, He J, Xu Y, Peng B.
europepmc   +1 more source

Lipid Nanoparticle-Mediated RNAi Against GIPC1 Overcomes Chemoresistance in Pancreatic Ductal Adenocarcinoma. [PDF]

Pharmaceutics
Madamsetty VS, Rachamala HK, Dutta SK, Wang E, Pal K, Mukhopadhyay D.   +5 more
europepmc   +1 more source

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Lipid Nanoparticle (LNP) Enables mRNA Delivery for Cancer Therapy

Advanced Materials, 2023
Messenger RNA (mRNA) has received great attention in the prevention and treatment of various diseases due to the success of coronavirus disease 2019 (COVID‐19) mRNA vaccines (Comirnaty and Spikevax).
Yan Zong, Yi Lin, Tuo Wei, Qiang Cheng
semanticscholar   +3 more sources

Lipid Nanoparticle Technologies for Nucleic Acid Delivery: A Nanoarchitectonics Perspective

Advanced Functional Materials, 2022
Lipid‐based nanoparticles have emerged as a clinically viable platform technology to deliver nucleic acids for a wide range of healthcare applications. Within this scope, one of the most exciting areas of recent progress and future innovation potential ...
A. R. Ferhan, Soohyun Park, Hyeon-Jin Park, Hyunhyuk Tae, Joshua A. Jackman, Nam‐Joon Cho   +5 more
semanticscholar   +3 more sources

Close the cancer–immunity cycle by integrating lipid nanoparticle–mRNA formulations and dendritic cell therapy

Nature Nanotechnology, 2023
Yuebao Zhang, Xucheng Hou, Shi Du, Yonger Xue, Jingyue Yan, Diana D. Kang, Yichen Zhong, Chang Wang, Binbin Deng, D. McComb, Yizhou Dong   +10 more
semanticscholar   +3 more sources

Carbohydrate anchored lipid nanoparticles

International Journal of Pharmaceutics, 2022
Nanotechnology has been a dynamic field for formulation scientists with multidisciplinary research being conducted worldwide. Advancements in development of functional nanosystems have led to evolution of breakthrough technologies. Lipidic nanosystems, in particular, are highly preferred owing to their non-immunogenic safety profiles along with a range
Pratik, Kakade, Arkasubhro, Chatterjee, Anjali, Pandya, John, Disouza, Vandana, Patravale   +4 more
openaire   +2 more sources

Lipid nanoparticle-mediated drug delivery to the brain.

Advanced Drug Delivery Reviews, 2023
Lipid nanoparticles (LNPs) have revolutionized the field of drug delivery through their applications in siRNA delivery to the liver (Onpattro) and their use in the Pfizer-BioNTech and Moderna COVID-19 mRNA vaccines.
Purva Khare, Sara X. Edgecomb, Christine M. Hamadani, Eden E. L. Tanner, D. Manickam   +4 more
semanticscholar   +1 more source