Results 1 to 10 of about 150,019 (199)
Lipid Peroxidation in Neurodegeneration [PDF]
Neurodegenerative diseases have multiple social and economic impacts on society, and they are the cause of millions of deaths every year [...]
openaire +3 more sources
Lipid peroxidation (LPO) is initiated by the attack of free radicals (eg OH ·, O2- and H2O2) on cellular or organelle membranes phospholipids or polyunsaturated fatty acids (PUFA), and with the formation of various types of aldehydes, ketones, alkanes, carboxylic acids and polymerization products. It is an autoxidation process that results.
Onur, Yaman, Suzan, Adnan, Ayhanci,
openaire +3 more sources
Effect of Exercise on Lipid Peroxidation [PDF]
Purpose: The effect of physical exercise on lipid peroxidation was investigated. Method: 27 healthy young adult male subjects were included in this study. Urine samples were collected before and after exercises. Urinary malondialdehyde and creatinine levels (Cr) were measured. Results: Urinary malondialdehyde levels were increased by exercise.
Demir, Süleyman+4 more
openaire +6 more sources
Lipid peroxides and atherosclerosis. [PDF]
Plasma lipid peroxide concentrations were measured in 100 patients with occlusive arterial disease proved angiographically (50 patients with ischaemic heart disease, 50 with peripheral arterial disease) and compared with values in 75 control patients with no clinical evidence of atherosclerosis.
A. Freeman+3 more
openaire +2 more sources
Lipid peroxidation in eclampsia
In order to investigate the extent of lipid peroxidation in hypertensive disorders of pregnancy, a case-control study was designed. Eight eclamptic women were matched with women with severe pre-eclampsia (n = 8) and healthy pregnant controls (n = 8).
G J Hofmeyr+2 more
openaire +3 more sources
Lipid Peroxidation and Antioxidant Protection
Lipid peroxidation (LP) is the most important type of oxidative-radical damage in biological systems, owing to its interplay with ferroptosis and to its role in secondary damage to other biomolecules, such as proteins. The chemistry of LP and its biological consequences are reviewed with focus on the kinetics of the various processes, which helps ...
openaire +4 more sources
HDL, lipid peroxidation, and atherosclerosis [PDF]
Genetic, clinical, and pharmacological studies implicate elevated levels of LDL in the pathogenesis of atherosclerotic vascular disease, the leading cause of death in industrialized societies (1). Paradoxically, native LDL fails to exert potentially atherogenic effects in vitro, suggesting that it must be modified to promote vascular disease.
Baohai Shao, Jay W. Heinecke
openaire +2 more sources
The mechanism of NADPH-dependent lipid peroxidation. The propagation of lipid peroxidation.
NADPH-dependent lipid peroxidation occurs in two distinct sequential radical steps. The first step, initiation, is the ADP-perferryl ion-catalyzed formation of low levels of lipid hydroperoxides. The second step, propagation, is the iron-catalyzed breakdown of lipid hydroperoxides formed during initiation generating reactive intermediates and products ...
F O O'Neal+3 more
openaire +2 more sources
Nitric oxide and lipid peroxidation
Nitric oxide can both promote and inhibit lipid peroxidation. By itself, nitric oxide acts as a potent inhibitor of the lipid peroxidation chain reaction by scavenging propagatory lipid peroxyl radicals. In addition, nitric oxide can also inhibit many potential initiators of lipid peroxidation, such as peroxidase enzymes.
Neil Hogg, Balaraman Kalyanaraman
openaire +3 more sources
Lipid peroxidation in women with epilepsy
Lipid peroxidation is an indicator of free radical metabolism and oxidative stress in human beings and other organisms. Malondialdehyde (MDA), an end product of lipid peroxidation, is a metabolite that can be readily estimated in serum samples. Excess oxidative stress may be a final common pathway through which anti epileptic drugs may exert their ...
D Deepa, Sanjeev V Thomas, B Jayakumari
openaire +4 more sources