Results 1 to 10 of about 369,467 (261)
Lipid Peroxidation in Neurodegeneration [PDF]
Antioxidants, 2021 Neurodegenerative diseases have multiple social and economic impacts on society, and they are the cause of millions of deaths every year [...]
Consuelo Cháfer-Pericás
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ACSL4 at the helm of the lipid peroxidation ship: a deep-sea exploration towards ferroptosis. [PDF]
Front PharmacolLipid peroxidation stands as a prominent hallmark and a prerequisite for the onset of ferroptosis. Lipid metabolism holds a pivotal role in regulating this process, forming the metabolic foundation for cellular sensitivity to ferroptosis.
Jiang Y, Zhang M, Sun M.
europepmc +2 more sources
Lipid Peroxidation and Antioxidant Protection
Biomolecules, 2023 Lipid peroxidation (LP) is the most important type of oxidative-radical damage in biological systems, owing to its interplay with ferroptosis and to its role in secondary damage to other biomolecules, such as proteins. The chemistry of LP and its biological consequences are reviewed with focus on the kinetics of the various processes, which helps ...
Luca Valgimigli
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HDL, lipid peroxidation, and atherosclerosis [PDF]
Journal of Lipid Research, 2009 Genetic, clinical, and pharmacological studies implicate elevated levels of LDL in the pathogenesis of atherosclerotic vascular disease, the leading cause of death in industrialized societies (1). Paradoxically, native LDL fails to exert potentially atherogenic effects in vitro, suggesting that it must be modified to promote vascular disease.
Baohai Shao, Jay W. Heinecke
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Correlation of Lipid Peroxidation with Glycated Haemoglobin Levels in Diabetes Mellitus [PDF]
Online Journal of Health & Allied Sciences, 2011 Reactive oxygen species are crucial to normal biological processes; they are potentially dangerous and are commonly referred to as prooxidants. The reactive oxygen intermediates can cause direct cellular injury by including lipid and protein peroxidation
Bhat, GP, Varashree, BS
core +2 more sources
Endogenous Derivatives of Linoleic Acid and their Stable Analogs Are Potential Pain Mediators
JID Innovations, 2023 Psoriasis is characterized by intense pruritus, with a subset of individuals with psoriasis experiencing thermal hypersensitivity. However, the pathophysiology of thermal hypersensitivity in psoriasis and other skin conditions remains enigmatic. Linoleic
Joshua J. Wheeler +7 more
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Metabolites, 2023 A previous report showed that 12-week lowering of dietary omega-6 linoleic acid (LA) coupled with increased omega-3 polyunsaturated fatty acid (PUFA) intake (H3-L6 diet) reduced headache frequency and improved quality of life in patients with chronic ...
Qing Shen +9 more
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Frontiers in Pain Research, 2023 BackgroundMigraine is a prevalent disabling condition often associated with comorbid physical and psychological symptoms that contribute to impaired quality of life and disability.
Keturah R. Faurot +15 more
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Acta Neuropathologica Communications, 2023 In sporadic Alzheimer’s disease (sAD) specific regions, layers and neurons accumulate hyperphosphorylated Tau (pTau) and degenerate early while others remain unaffected even in advanced disease.
Christopher E. Ramsden +11 more
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Journal of Lipid Research, 2023 Natural variations in the 13C:12C ratio (carbon-13 isotopic abundance [δ13C]) of the food supply have been used to determine the dietary origin and metabolism of fatty acids, especially in the n-3 PUFA biosynthesis pathway.
Daniel K. Chen +10 more
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