Mitochondrial Lipid Peroxidation Is Responsible for Ferroptosis
Cells, 2023 Ferroptosis induced by erastin (an inhibitor of cystine transport) and butionine sulfoximine (an inhibitor of glutathione biosynthesis) was prevented by the mitochondria-targeted antioxidants SkQ1 and MitoTEMPO.
Konstantin G. Lyamzaev +4 more
doaj +2 more sources
Studies on the hyperplasia ('regeneration') of the rat liver following partial hepatectomy. Changes in lipid peroxidation and general biochemical aspects [PDF]
, 1990 Using the experimental model of partial hepatectomy in the rat, we have examined the relationship between cell division and lipid peroxidation activity. In rats entrained to a regime of 12 h light/12 h dark and with a fixed 8 h feeding period in the dark
Maddix, SP +9 more
core +7 more sources
A meta-analysis of lipid peroxidation markers in major depression
Neuropsychiatric Disease and Treatment, 2015 Graham Mazereeuw,1,2 Nathan Herrmann,1,3 Ana C Andreazza,2–4 Maisha M Khan,1 Krista L Lanctôt1–3 1Hurvitz Brain Sciences Program, Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, ON, Canada; 2Department of ...
Mazereeuw G +4 more
doaj +1 more source
Studies on ferrous ion-induced lipid peroxidation of rat liver mitochondria. I. Effect of inorganic phosphate [PDF]
, 1974 Effect of inorganic phosphate on ferrous ion- and ascorbate-induced lipid. peroxidations of isolated rat liver mitochondria was investigated. As a result it has been shown that phosphate accelerates the ferrous ion.induced lipid peroxidation; namely ...
Yamamoto, Goki +4 more
core +1 more source
Elevated levels of erythrocyte-conjugated dienes indicate increased lipid peroxidation in schistosomiasis mansoni patients [PDF]
, 2004 Schistosoma mansoni causes liver disease by inducing granulomatous inflammation. This favors formation of reactive oxygen species, including superoxide ions, hydrogen peroxide and hydroxyl radicals all of which may induce lipid peroxidation.
Owen, JS +7 more
core +1 more source
Ribonucleotide reductase in dividing cells: Purification and inhibition studies with 4-hydroxynonenal [PDF]
, 1992 This thesis was submitted for the degree of Doctor of Philosophy and was awarded by Brunel University.1). The effect of temperature, P450 inhibitors (pyrazole and imidazole), sulphydryl reagents (iodoacetamide and N-ethyl maleimide) and glutathione on ...
Li, Li
core +5 more sources
Vicious cycle of lipid peroxidation and iron accumulation in neurodegeneration
Neural Regeneration Research, 2023 Lipid peroxidation and iron accumulation are closely associated with neurodegenerative diseases, such as Alzheimer’s, Parkinson’s, and Huntington’s diseases, or neurodegeneration with brain iron accumulation disorders.
Irene Villalón-García +10 more
doaj +1 more source
The Peroxisome Proliferator-activated Receptor γ (PPARγ) Controls Natural Protective Mechanisms against Lipid Peroxidation in Amyotrophic Lateral Sclerosis [PDF]
, 2012 Recent evidence highlights the peroxisome proliferator-activated receptors (PPARs) as critical neuroprotective factors in several neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). To gain new mechanistic insights into the role of
Maggi, Adriana +8 more
core +1 more source
Accenting Lipid Peroxidation [PDF]
, 2021 Lipid peroxidation can occur via either enzymatic or nonenzymatic reactions due to excess production of free radical molecules. This process culminates in cellular damage causing various diseases.
core +1 more source
Evaluating the In Vitro Potential of Natural Extracts to Protect Lipids from Oxidative Damage
Antioxidants, 2020 Lipid peroxidation is a chemical reaction known to have negative impacts on living organisms’ health and on consumer products’ quality and safety.
Rafael Félix +5 more
doaj +1 more source