Results 11 to 20 of about 1,407,330 (363)
Lipid Peroxidation and Iron Metabolism: Two Corner Stones in the Homeostasis Control of Ferroptosis
International Journal of Molecular Sciences, 2022 Regulated cell death (RCD) has a significant impact on development, tissue homeostasis, and the occurrence of various diseases. Among different forms of RCD, ferroptosis is considered as a type of reactive oxygen species (ROS)-dependent regulated ...
L. Rochette +5 more
semanticscholar +1 more source
Cell Death via Lipid Peroxidation and Protein Aggregation Diseases
Biology, 2021 Lipid peroxidation of cellular membranes is a complicated cellular event, and it is both the cause and result of various diseases, such as ischemia-reperfusion injury, neurodegenerative diseases, and atherosclerosis.
Katsuya Iuchi +2 more
doaj +1 more source
Hydropersulfides inhibit lipid peroxidation and ferroptosis by scavenging radicals
Nature Chemical Biology, 2022 Ferroptosis is a type of cell death caused by radical-driven lipid peroxidation, leading to membrane damage and rupture. Here we show that enzymatically produced sulfane sulfur (S^0) species, specifically hydropersulfides, scavenge endogenously generated
U. Barayeu +12 more
semanticscholar +1 more source
Cell Death Discovery, 2022 Compared to cancer cells, macrophages are inert to lipid peroxidation-triggered, iron-dependent cell death known as ferroptosis. Mechanisms underlying macrophage resistance towards ferroptosis are largely obscure.
Dmitry Namgaladze +2 more
doaj +1 more source
Role of Nano-fertilizer in Plants Nutrient Use Efficiency (NUE)- A mini-review [PDF]
J Gene Engg Bio Res, 5(1), 75-81. 2023, 2023 Over the past half-century, the combination of technology and innovation has been developed to manage the negative impact of synthetic fertilizer on land ecosystems to identify the limitations of sustainability and optimize agricultural systems. The application of nano-fertilizers has achieved considerable interest due to their significant role as ...
arxiv +1 more source
Mitochondrial Lipid Peroxidation Is Responsible for Ferroptosis
Cells, 2023 Ferroptosis induced by erastin (an inhibitor of cystine transport) and butionine sulfoximine (an inhibitor of glutathione biosynthesis) was prevented by the mitochondria-targeted antioxidants SkQ1 and MitoTEMPO.
Konstantin G. Lyamzaev +4 more
doaj +1 more source
Cell Death and Disease, 2021 Ferroptosis, a newly defined mode of regulated cell death caused by unbalanced lipid redox metabolism, is implicated in various tissue injuries and tumorigenesis. However, the role of ferroptosis in stem cells has not yet been investigated.
Qian Hu +10 more
semanticscholar +1 more source
Oxidative Medicine and Cellular Longevity, 2014 Lipid peroxidation can be described generally as a process under which oxidants such as free radicals attack lipids containing carbon-carbon double bond(s), especially polyunsaturated fatty acids (PUFAs).
A. Ayala, Mario F. Muñoz, S. Argüelles
semanticscholar +1 more source
Radiation-Induced Lipid Peroxidation Triggers Ferroptosis and Synergizes with Ferroptosis Inducers.
ACS Chemical Biology, 2020 Although radiation is widely used to treat cancers, resistance mechanisms often develop and involve activation of DNA repair and inhibition of apoptosis.
L. Ye +16 more
semanticscholar +1 more source
Vicious cycle of lipid peroxidation and iron accumulation in neurodegeneration
Neural Regeneration Research, 2023 Lipid peroxidation and iron accumulation are closely associated with neurodegenerative diseases, such as Alzheimer’s, Parkinson’s, and Huntington’s diseases, or neurodegeneration with brain iron accumulation disorders.
Irene Villalón-García +10 more
doaj +1 more source