Results 11 to 20 of about 369,467 (261)
Cell Death via Lipid Peroxidation and Protein Aggregation Diseases
Lipid peroxidation of cellular membranes is a complicated cellular event, and it is both the cause and result of various diseases, such as ischemia-reperfusion injury, neurodegenerative diseases, and atherosclerosis.
Katsuya Iuchi+2 more
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Hydroxy-epoxide and keto-epoxide derivatives of linoleic acid activate trigeminal neurons
Endogenous lipid mediators are proposed to contribute to headache and facial pain by activating trigeminal neurons (TN). We recently identified 11-hydroxy-epoxide- and 11-keto-epoxide derivatives of linoleic acid (LA) that are present in human skin and ...
Suzanne Doolen+2 more
doaj +1 more source
Compared to cancer cells, macrophages are inert to lipid peroxidation-triggered, iron-dependent cell death known as ferroptosis. Mechanisms underlying macrophage resistance towards ferroptosis are largely obscure.
Dmitry Namgaladze+2 more
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Mitochondrial Lipid Peroxidation Is Responsible for Ferroptosis
Ferroptosis induced by erastin (an inhibitor of cystine transport) and butionine sulfoximine (an inhibitor of glutathione biosynthesis) was prevented by the mitochondria-targeted antioxidants SkQ1 and MitoTEMPO.
Konstantin G. Lyamzaev+4 more
doaj +1 more source
Lipid peroxidation (LPO) is initiated by the attack of free radicals (eg OH ·, O2- and H2O2) on cellular or organelle membranes phospholipids or polyunsaturated fatty acids (PUFA), and with the formation of various types of aldehydes, ketones, alkanes, carboxylic acids and polymerization products. It is an autoxidation process that results.
Onur, Yaman, Suzan, Adnan, Ayhanci,
openaire +3 more sources
Lipid peroxidation is essential for α-synuclein-induced cell death. [PDF]
Parkinson's disease is the second most common neurodegenerative disease and its pathogenesis is closely associated with oxidative stress. Deposition of aggregated α-synuclein (α-Syn) occurs in familial and sporadic forms of Parkinson's disease.
Abramov, AY+5 more
core +2 more sources
Turmeric and black pepper spices decrease lipid peroxidation in meat patties during cooking. [PDF]
Spices are rich in natural antioxidants and have been shown to be potent inhibitors of lipid peroxidation during cooking of meat. Turmeric contains unique conjugated curcuminoids with strong antioxidant activity. Piperine, one of the main constituents of
Heber, David+6 more
core +2 more sources
OXIDATIVE CHANGES OF LIPIDS, PROTEINS AND ANTIOXIDANTS IN YOGURT DURING THE SHELF LIFE [PDF]
Background: Oxidation processes in milk and yogurt during the shelf life can result in an alteration of protein and lipid constituents. Therefore, the antioxidant properties of yogurt in standard conditions of preservation were evaluated. Results: Total
Bellamio, Marco+7 more
core +1 more source
Vicious cycle of lipid peroxidation and iron accumulation in neurodegeneration
Lipid peroxidation and iron accumulation are closely associated with neurodegenerative diseases, such as Alzheimer’s, Parkinson’s, and Huntington’s diseases, or neurodegeneration with brain iron accumulation disorders.
Irene Villalón-García+10 more
doaj +1 more source
Lipid peroxidation in the serum of hypothyroid patients (In Gorgan-South East of Caspian Sea) [PDF]
This study was designed to determine if lipid peroxidation can be modified by hypothyroidism. Twenty eight subjects with hypothyroidism and 33 euthyroid subjects participated in this study (2007).
Ahmadi, A.+4 more
core +1 more source