Results 11 to 20 of about 1,632,742 (358)
Bio-Protocol, 2018 Lipid peroxidation is a physiological indicator of both biotic and abiotic stress responses, hence is often used as a biomarker to assess stress-induced cell damage or death.
Jay Awasthi +5 more
doaj +3 more sources
Journal of Lipid Research, 2023 Natural variations in the 13C:12C ratio (carbon-13 isotopic abundance [δ13C]) of the food supply have been used to determine the dietary origin and metabolism of fatty acids, especially in the n-3 PUFA biosynthesis pathway.
Daniel K. Chen +10 more
doaj +1 more source
Polyunsaturated Fatty Acids Drive Lipid Peroxidation during Ferroptosis
Cells, 2023 Ferroptosis is a form of regulated cell death that is intricately linked to cellular metabolism. In the forefront of research on ferroptosis, the peroxidation of polyunsaturated fatty acids has emerged as a key driver of oxidative damage to cellular ...
Michael S. Mortensen +2 more
semanticscholar +1 more source
Lipid Peroxidation in Neurodegeneration
Antioxidants, 2021 Neurodegenerative diseases have multiple social and economic impacts on society, and they are the cause of millions of deaths every year [...]
Consuelo Cháfer-Pericás
doaj +1 more source
Cell Death via Lipid Peroxidation and Protein Aggregation Diseases
Biology, 2021 Lipid peroxidation of cellular membranes is a complicated cellular event, and it is both the cause and result of various diseases, such as ischemia-reperfusion injury, neurodegenerative diseases, and atherosclerosis.
Katsuya Iuchi +2 more
doaj +1 more source
Lipid peroxidation in osteoarthritis: focusing on 4-hydroxynonenal, malondialdehyde, and ferroptosis
Cell Death Discovery, 2023 Osteoarthritis (OA) is a multifactorial and increasingly prevalent degenerative disease that affects the whole joint. The pathogenesis of OA is poorly understood and there is a lack of therapeutic interventions to reverse the pathological process of this
Xiong Zhang +7 more
semanticscholar +1 more source
Hydroxy-epoxide and keto-epoxide derivatives of linoleic acid activate trigeminal neurons
Neurobiology of Pain, 2020 Endogenous lipid mediators are proposed to contribute to headache and facial pain by activating trigeminal neurons (TN). We recently identified 11-hydroxy-epoxide- and 11-keto-epoxide derivatives of linoleic acid (LA) that are present in human skin and ...
Suzanne Doolen +2 more
doaj +1 more source
Lipid Peroxidation and Iron Metabolism: Two Corner Stones in the Homeostasis Control of Ferroptosis
International Journal of Molecular Sciences, 2022 Regulated cell death (RCD) has a significant impact on development, tissue homeostasis, and the occurrence of various diseases. Among different forms of RCD, ferroptosis is considered as a type of reactive oxygen species (ROS)-dependent regulated ...
L. Rochette +5 more
semanticscholar +1 more source
Hydropersulfides inhibit lipid peroxidation and ferroptosis by scavenging radicals
Nature Chemical Biology, 2022 Ferroptosis is a type of cell death caused by radical-driven lipid peroxidation, leading to membrane damage and rupture. Here we show that enzymatically produced sulfane sulfur (S^0) species, specifically hydropersulfides, scavenge endogenously generated
U. Barayeu +12 more
semanticscholar +1 more source
Cell Death Discovery, 2022 Compared to cancer cells, macrophages are inert to lipid peroxidation-triggered, iron-dependent cell death known as ferroptosis. Mechanisms underlying macrophage resistance towards ferroptosis are largely obscure.
Dmitry Namgaladze +2 more
doaj +1 more source