Results 91 to 100 of about 87,561 (363)

Metabolic and oxidative status of West African dwarf does at different reproductive stages in southwest Nigeria

open access: yesBulletin of the National Research Centre, 2019
Background A study was conducted to investigate changes in oxidative stress indicators of West African dwarf (WAD) goats at different reproductive stages.
Abubakar Olatunji Jimoh   +2 more
doaj   +1 more source

Oxidative stress and the fetotoxicity of alcohol consumption during pregnancy. [PDF]

open access: yes, 1996
Pregnant Quackenbush Special mice were exposed to ethanol under semiacute (3.0 g/kg body weight intragastrically, days 7 to 12 of pregnancy), and chronic conditions (15% ethanol in drinking water for 5 weeks before and during pregnancy) to assess whether
Amini, Seyed Asadollah.   +3 more
core   +1 more source

Metal Nanoclusters for Cancer Imaging and Treatment

open access: yesAdvanced Functional Materials, EarlyView.
This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu   +5 more
wiley   +1 more source

Cytoprotective effects of melatonin against amitriptyline-induced toxicity in isolated rat hepatocytes [PDF]

open access: yes, 2015
Purpose: Amitriptyline, one of the commonly used tricyclic antidepressants, caused rare but severe hepatotoxicity in patients who received it continuously. Previous findings showed that the intermediate metabolites of amitriptyline produced by CYP450 are
Dastmalchi, S.   +3 more
core   +1 more source

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

open access: yesAdvanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu   +5 more
wiley   +1 more source

Mechanisms linking colorectal cancer to the consumption of (processed) red meat : a review [PDF]

open access: yes, 2015
Colorectal cancer (CRC) is the third most commonly diagnosed cancer in the world. The vast majority of CRC cases have been linked to environmental causes rather than to heritable genetic changes.
De Smet, Stefaan   +3 more
core   +2 more sources

Nitric oxide and lipid peroxidation

open access: yesBiochimica et Biophysica Acta (BBA) - Bioenergetics, 1999
Nitric oxide can both promote and inhibit lipid peroxidation. By itself, nitric oxide acts as a potent inhibitor of the lipid peroxidation chain reaction by scavenging propagatory lipid peroxyl radicals. In addition, nitric oxide can also inhibit many potential initiators of lipid peroxidation, such as peroxidase enzymes.
Neil Hogg, Balaraman Kalyanaraman
openaire   +3 more sources

Antibody‐Programmable Bimetallic Nanozymes for Transcriptional Blockade Therapy in HER2/ER‐Positive Breast Cancer

open access: yesAdvanced Functional Materials, EarlyView.
Zr‐Fe MOF@Ribociclib@Herceptin (ZFRH) efficiently targets/kills Human Epidermal Growth Factor Receptor 2/Estrogen Receptor‐positive (HER2/ER+) breast cancer cells. It combats tumors by: 1) Elevating ROS, altering redox balance; 2) Inhibiting transcription; 3) Inducing pyroptosis.
Hongkun Miao   +8 more
wiley   +1 more source

Reactive Oxygen Species, Lipid Peroxidation and Antioxidative Defense Mechanism

open access: yesNotulae Botanicae Horti Agrobotanici Cluj-Napoca, 2013
Lipid peroxidation can be defined as the oxidative deterioration of lipids containing any number of carbon-carbon double bonds. Lipid peroxidation is a well-established mechanism of cellular injury in both plants and animals, and is used as an indicator ...
Hossam S. EL-BELTAGI, Heba I. MOHAMED
doaj   +1 more source

Turmeric and black pepper spices decrease lipid peroxidation in meat patties during cooking. [PDF]

open access: yes, 2015
Spices are rich in natural antioxidants and have been shown to be potent inhibitors of lipid peroxidation during cooking of meat. Turmeric contains unique conjugated curcuminoids with strong antioxidant activity. Piperine, one of the main constituents of
Heber, David   +6 more
core   +2 more sources

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