Results 171 to 180 of about 1,515,713 (252)

Rocket‐Inspired Sequentially Targeted Nanotherapeutics for Mitochondrial Regulation and Inflammatory Reprogramming in Ischemic Stroke

open access: yesAdvanced Science, EarlyView.
A novel neutrophil‐hitchhiking, rocket‐inspired nanoplatform is developed to cross the blood‐brain barrier for sequential, spatiotemporal drug delivery. By responsive surface transformation in the ischemic penumbra, it precisely targets mitochondria to suppress Drp1‐mediated fission.
He Bai   +17 more
wiley   +1 more source

Innovative Test Strip‐Based Colorimetric Sensors Integrated With Affinity Chromatography: Acetylcholinesterase Inhibitor Screening Breakthrough in Lycium Barbarum Leaves

open access: yesAdvanced Science, EarlyView.
Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa   +11 more
wiley   +1 more source

Gut‐Liver Translocation of Bacteroides Uniformis Alleviates Advanced Metabolic Dysfunction‐Associated Steatotic Liver Disease by Suppressing Hepatocyte Ferroptosis via Propionic Acid Secretion

open access: yesAdvanced Science, EarlyView.
Systematic characterization of the liver‐resident microbiota in advanced metabolic dysfunction‐associated steatotic liver disease (MASLD) reveals a consistent depletion of Bacteroides uniformis (B. uniformis) in both hepatic and gut microbial communities. Oral gavage of B.
Haiyang Liu   +4 more
wiley   +1 more source

Lipid peroxides and human diseases

Chemistry and Physics of Lipids, 1987
K. Yagi
exaly   +2 more sources

Lipid peroxidation and lipid peroxide detected by chemiluminescence

Free Radical Biology and Medicine, 1987
This article emphasizes the advantages of using a luminescence spectrometer based on photon counting techniques for the detection of lipid peroxidation. An overview is presented of how chemiluminescence can be stimulated in the luminol-cytochrome c heme peptide system as an assay for lipid hydroperoxides.
T, Iwaoka, F, Tabata, T, Takahashi
openaire   +2 more sources

Lipid peroxides and thrombosis

Bulletin of Experimental Biology and Medicine, 1979
In incubation of rabbit platelets with ADF, adrenalin, serotonin and thrombin the level of hydroxyperoxides serotonin and thrombin the level of hydroxyperoxides serotonin and thrombin the level of hydroxyperoxides they show, determined with respect to malonic dialdehyde, rises simultaneously with the enhancement of aggregation activity.
A A, Kubatiev, S V, Andreev
openaire   +2 more sources

Measurement of Lipid Peroxidation

Current Protocols in Toxicology, 1999
AbstractThere is currently considerable interest in what is termed “oxidative stress,” or the oxidation of biological macromolecules, with emphasis on its involvement in various diseases and toxicities and methods to limit either its occurrence or effects.
C A, Reilly, S D, Aust
openaire   +2 more sources

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