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Lipid peroxidation in erythrocytes
Chemistry and Physics of Lipids, 1987Erythrocytes might be expected to be highly susceptible to peroxidation. Their membranes are rich in polyunsaturated fatty acids; they are continuously exposed to high concentrations of oxygen; and they contain a powerful transition metal catalyst. In fact, autoxidation is held in check in vivo by extremely efficient protective antioxidant mechanisms ...
M R, Clemens, H D, Waller
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Lipid peroxidation in neurodegeneration
Clinica Chimica Acta, 2019Neurodegenerative diseases have great social and economic impact and cause millions of deaths every year. The potential molecular mechanisms in these pathologies have been widely studied and implicate lipid peroxidation as an important factor in the development of neurodegenerative disorders such as Alzheimer's, Parkinson's and Huntington's diseases ...
Carmen Peña-Bautista +3 more
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Lipid peroxidation in homocysteinaemia
Journal of Inherited Metabolic Disease, 1992Homocysteinaemia due to cystathione synthase deficiency (CSD: McKusick 236200) is a rare autosomal recessive inborn error of methionine metabolism. The most life-threatening complications caused by CSD are thromboembolism and vascular abnormalities.
H J, Blom +7 more
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Measurement of Lipid Peroxidation
Free Radical Research, 1998Lipid peroxidation results in the formation of conjugated dienes, lipid hydroperoxides and degradation products such as alkanes, aldehydes and isoprostanes. The approach to the quantitative assessment of lipid peroxidation depends on whether the samples involve complex biological material obtained in vivo, or whether the samples involve relatively ...
K, Moore, L J, Roberts
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Critical Reviews in Oncology/Hematology, 1993
Lipid peroxidation, firstly described as a mechanism of lipid deterioration by chemists, is now considered as a major mechanism of elementary lesion in living cells, and in many cases the major cause for their death. In living animals, it was firstly described to increase after irradiation [23,32,252] and then in vitamin E deficiency [57,258,259].
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Lipid peroxidation, firstly described as a mechanism of lipid deterioration by chemists, is now considered as a major mechanism of elementary lesion in living cells, and in many cases the major cause for their death. In living animals, it was firstly described to increase after irradiation [23,32,252] and then in vitamin E deficiency [57,258,259].
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Lipid peroxidation in spermatozoa
Proceedings of the Royal Society of London. Series B. Biological Sciences, 1973Abstract Ram spermatozoa produce aerobically an organic peroxide which can be determined quantitatively by the thiobarbituric acid reaction. The reaction is more intense in spermatozoa that have been stored at 5°C. Cold shock and homogenization release from spermatozoa a substance, presumably a lipid, which provides the substrate for
R, Jones, T, Mann
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Peroxidation of liposomal lipids
European Biophysics Journal, 2007Free radicals, formed via different mechanisms, induce peroxidation of membrane lipids. This process is of great importance because it modifies the physical properties of the membranes, including its permeability to different solutes and the packing of lipids and proteins in the membranes, which in turn, influences the membranes' function. Accordingly,
Edit, Schnitzer +2 more
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Inhibition of lipid peroxidation
Biological Trace Element Research, 1997Lipid peroxy radicals (ROO.) were detected by electron spin resonance (ESR) at low temperature after formation by addition of H2O2 into a suspension of mice lymphocytes. If lymphocytes were treated with selenomethionine (Se-Met) prior to addition of H2O2, ROO. formation was inhibited in a fashion that was dependent on Se-Met concentration. Formation of
E, Sun +5 more
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Lipid Peroxidation in Diabetes Mellitus
Antioxidants & Redox Signaling, 2005There is considerable evidence that hyperglycemia represents the main cause of complications of diabetes mellitus (DM), and oxidative stress resulting from increased generation of reactive oxygen species plays a crucial role in their pathogenesis. In fact, in the absence of an appropriate response from endogenous antioxidant mechanisms, the redox ...
DAVI', Giovanni, FALCO A, PATRONO C.
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Lipid peroxidation in mitochondria
Free Radical Biology and Medicine, 1988The present review article takes into consideration the most important aspects of lipid peroxidation in mitochondria. Firstly the various ways by which lipid peroxidation is induced and the relevant mechanisms are described and discussed. After examining the major effects of lipid peroxidation on mitochondrial enzymes and bioenergetic functions, some ...
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