Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise +2 more
wiley +1 more source
Membrane lipid raft homeostasis is directly linked to neurodegeneration. [PDF]
Moll T +6 more
europepmc +1 more source
ABSTRACT Violae tianshanicae herba (VTH), a widely used crude drug in Uyghur medicine in China, is renowned for its immunomodulatory, anti‐inflammatory, antibacterial, antiviral, and antidiabetic activities, with notable efficacy in treating asthma. However, systematic research on its quality markers (Q‐markers) remains limited, underscoring the need ...
Haifeng Liu +6 more
wiley +1 more source
The role of RNA structural motifs in RNA-lipid raft interaction. [PDF]
Mańka R +5 more
europepmc +1 more source
AIBP regulates TRPV1 activation in chemotherapy-induced peripheral neuropathy by controlling lipid raft dynamics and proximity to TLR4 in dorsal root ganglion neurons. [PDF]
Navia-Pelaez JM +10 more
europepmc +1 more source
Toxic mechanisms of amyloid oligomers and therapeutic strategies
Abstract Amyloid oligomers are increasingly recognized as the major toxic contributors across protein‐misfolding disorders. In this review, we cover mechanistic evidence showing how these transient and structurally heterogeneous oligomers disrupt cellular homeostasis by: (i) permeabilizing lipid membranes and forming ion‐conducting pores; (ii ...
Magdalena I. Ivanova +2 more
wiley +1 more source
Combined Effects of Atorvastatin and Glucose Deprivation on Metabolic Stress and Lipid-Raft Disruption in Glioblastoma and Breast Cancer Cells. [PDF]
Alshaer W +6 more
europepmc +1 more source
The prohibitin complex regulates macrophage fatty acid composition, plasma membrane packing, and lipid raft-mediated inflammatory signaling. [PDF]
Matthews CEP +19 more
europepmc +1 more source
Glimepiride protects neurons against amyloid-beta-induced synapse damage [PDF]
Bate, C +5 more
core +1 more source

