The role of the host—Neutrophil biology
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple+4 more
wiley +1 more source
Cutting Edge: B Cell Antigen Receptor Signaling Occurs Outside Lipid Rafts in Immature B Cells [PDF]
Tim W. Sproul+3 more
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The first experimental identification of the IG head structure of naturally occurring plant GIPCs in Brassicaceae was achieved through the chemical synthesis of three hexose‐type IGs containing d‐glucose, d‐galactose, or d‐mannose as the second monosaccharide linked to d‐glucuronic acid‐α(1→2)‐myo‐inositol.
Yuta Umemura+11 more
wiley +1 more source
Fluorescence-Based Evaluation of the Partitioning of Lipids and Lipidated Peptides into Liquid-Ordered Lipid Microdomains: A Model for Molecular Partitioning into “Lipid Rafts” [PDF]
Tianyun Wang+2 more
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Continuous Flow Block Copolymer Nanoaggregate Synthesis and Their Flow Dialysis Purification
This work details the methodology for the synthesis of block copolymer nanoparticles through continuous flow self‐assembly and purification via flow dialysis. Nanoaggregates are formed by mixing block copolymer solutions in THF with water, followed by dialysis to eliminate excess solvent.
Gayathri Dev Ammini+2 more
wiley +1 more source
Molecular switches in lipid rafts [PDF]
Leslie A. Cary, Jonathan A. Cooper
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Monitoring Receptor Clustering by Aggregation‐Induced Emission
Receptor clustering induced by molecular recognition: AIE‐functionalized bisphosphonate receptors are embedded in a lipid bilayer. Upon addition of a cationic messenger, they undergo dimerization and send out a fluorescence signal. This study introduces a simple signal transduction system that mimics the receptor tyrosine kinase mechanism by employing ...
Robert Bekus+4 more
wiley +1 more source
Conditions for extreme sensitivity of protein diffusion in membranes to cell environments
We study protein diffusion in multicomponent lipid membranes close to a rigid substrate separated by a layer of viscous fluid. The large-distance, long-time asymptotics for Brownian motion are calculated using a nonlinear stochastic Navier-Stokes ...
Baumgart+6 more
core +2 more sources
Mutant RBL Mast Cells Defective in FcεRI Signaling and Lipid Raft Biosynthesis Are Reconstituted by Activated Rho-family GTPases [PDF]
Kenneth A. Field+5 more
openalex +1 more source
NIR II‐Guided Photoactivatable Silencing Polyplex Boosts Cancer Immunotherapy
Due to limitation of penetration therapy with first and second‐generation photodynamic therapy (PDT) photosensitizers, an NIR II‐guided photoactivatable complex was proposed via the self‐assembly of the photosensitive polymer PTSQ and the electrostatic adsorption of siPD‐L1 to enhance cancer immunotherapy.
Yuquan Zhang+10 more
wiley +1 more source