Results 11 to 20 of about 69,365 (334)

Transcriptomic landscape based on annotated clinical features reveals PLPP2 involvement in lipid raft-mediated proliferation signature of early-stage lung adenocarcinoma. [PDF]

J Exp Clin Cancer Res, 2023
Background Image-based screening improves the detection of early-stage lung adenocarcinoma (LUAD)but also highlights the issue of high false-positive diagnoses, which puts patients at a risk of unnecessary over-treatment.
Wang Y, Miao Z, Qin X, Yang Y, Wu S, Miao Q, Li B, Zhang M, Wu P, Han Y, Li B.   +10 more
europepmc   +4 more sources

Differential association of the Na+/H+ exchanger regulatory factor (NHERF) family of adaptor proteins with the raft- and the non-raft brush border membrane fractions of NHE3 [PDF]

Cellular Physiology and Biochemistry, 2013
Background/Aims: Trafficking, brush border membrane (BBM) retention, and signal-specific regulation of the Na+/H+ exchanger NHE3 is regulated by the Na+/H+ Exchanger Regulatory Factor (NHERF) family of PDZ-adaptor proteins, which enable the formation of ...
Chen, M. (Mingmin), deJonge, H. (Hugo), Donowitz, M. (Mark), Gessner, J.E. (Johannes), Lamprecht, G. (Georg), Lissner, S. (Simone), Luo, M. (Ma), Riederer, B. (Beat Michel), Seidler, U. (Ursula), Sultan, A. (Ayesha), Xia, W. (Weiliang), Yu, Q. (Qingbao), Yun, C.C. (Chris)   +12 more
core   +11 more sources

Genotype-induced changes in biophysical properties of frontal cortex lipid raft from APP/PS1 transgenic mice [PDF]

Frontiers in Physiology, 2012
Alterations in the lipid composition of lipid rafts have been demonstrated both in human brain and transgenic mouse models, and it has been postulated that aberrant lipid composition in lipid rafts is partly responsible for neuronal degeneration.
Mario Dı́az, Noemí Fabelo, Raquel Marín   +2 more
openalex   +3 more sources

Transmembrane Domain Length of Influenza a Virus M2 Does Not Determine Its Non-Lipid Raft Localization. [PDF]

Viruses
Influenza A virus expresses three envelope proteins, hemagglutinin (HA), neuraminidase (NA), and matrix protein 2 (M2). Of these, HA and NA associate with lipid rafts, whereas M2 remains in the peri-raft region.
Manzoor R, Okuya K, Yoshida R, Miyamoto H, Takada A.   +4 more
europepmc   +2 more sources

Primary cilia and lipid raft dynamics. [PDF]

Open Biol, 2021
Primary cilia, antenna-like structures of the plasma membrane, detect various extracellular cues and transduce signals into the cell to regulate a wide range of functions.
Nishimura Y, Yamakawa D, Uchida K, Shiromizu T, Watanabe M, Inagaki M.   +5 more
europepmc   +2 more sources

Lipid Raft Membrane Interactivity Correlating with Cyclooxygenase-2 Selectivity of Non-Steroidal Anti-Inflammatory Drugs. [PDF]

Membranes (Basel)
The primary mechanism of non-steroidal anti-inflammatory drugs (NSAIDs) is inhibition of prostaglandin production mediated by cyclooxygenase. Given the possible association of cyclooxygenase-2, but not cyclooxygenase-1, with membrane lipid rafts, we ...
Mizogami M, Iida H, Tsuchiya H.
europepmc   +2 more sources

HHcy Induces Pyroptosis and Atherosclerosis via the Lipid Raft-Mediated NOX-ROS-NLRP3 Inflammasome Pathway in apoE^-/- Mice. [PDF]

Cells, 2022
Lipid rafts play important roles in signal transduction, particularly in responses to inflammatory processes. The current study aimed to identify whether lipid raft-mediated inflammation contributes to hyperhomocysteinemia (HHcy)-accelerated ...
Liu S, Tao J, Duan F, Li H, Tan H.
europepmc   +2 more sources

α1-nAchR-Mediated Signaling Through Lipid Raft Is Required for Nicotine-Induced NLRP3 Inflammasome Activation and Nicotine-Accelerated Atherosclerosis

Frontiers in Cell and Developmental Biology, 2021
BackgroundNicotine exerts direct effects on multiple cell types in the cardiovascular system by associating with its high-affinity nicotinic acetylcholine receptors (nAchRs).
Fengqi Duan, Cheng Zeng, Sijun Liu, Jianfeng Gong, Jia Hu, Hongyu Li, Hongmei Tan, Hongmei Tan, Hongmei Tan   +8 more
doaj   +1 more source

ER exit sites mediated by the COPII adaptor sec24D selectively recruit lipid raft-preferring proteins for rapid ER export. [PDF]

Nat Commun
The determinants of sub-cellular trafficking for many membrane proteins are poorly understood. Lipid-driven membrane nanodomains known as lipid rafts have been widely implicated in post-Golgi traffic, but their involvement in protein sorting in the ...
Castello-Serrano I, Dagar S, Ippolito R, Levental KR, Levental I.   +4 more
europepmc   +2 more sources

Toluidine Blue for the Determination of Binding of Anionic Polysaccharides to Lipid Raft Domains by Absorption Spectroscopy. [PDF]

Membranes (Basel)
The complexes of negatively charged polysaccharides with lipid vesicles have been shown to have applications in medicine, bioremediation, water purification, and construction of nano-biosensors.
Gębczyńska S, Gdowska J, Mikos A, Gawrońska I, Janas T, Czogalla A, Janas T.   +6 more
europepmc   +2 more sources