Results 11 to 20 of about 1,129,041 (391)

Lipid Raft, Regulator of Plasmodesmal Callose Homeostasis

Plants, 2017
: The specialized plasma membrane microdomains known as lipid rafts are enriched by sterols and sphingolipids. Lipid rafts facilitate cellular signal transduction by controlling the assembly of signaling molecules and membrane protein trafficking ...
Arya Bagus Boedi Iswanto, Jae-Yean Kim
doaj   +2 more sources

Lipid raft size and lipid mobility in non-raft domains increase during aging and are exacerbated in APP/PS1 mice model of Alzheimer’s disease. Predictions from an agent-based mathematical model [PDF]

Frontiers in Physiology, 2016
A connection between lipid rafts and Alzheimer’s disease has been studied during the last decades. Mathematical modeling approaches have recently been used to correlate the effects of lipid composition changes in the physicochemical properties of raft ...
Guido eSantos, Mario L Diaz, Nestor V. Torres   +2 more
doaj   +3 more sources

Genotype-induced changes in biophysical properties of frontal cortex lipid raft from APP/PS1 transgenic mice

Frontiers in Physiology, 2012
Alterations in the lipid composition of lipid rafts have been demonstrated both in human brain and transgenic mouse models, and it has been postulated that aberrant lipid composition in lipid rafts is partly responsible for neuronal degeneration.
Mario L Diaz, Noemi eFabelo, Raquel eMarin   +2 more
doaj   +2 more sources

The mystery of membrane organization: composition, regulation and roles of lipid rafts

Nature Reviews Molecular Cell Biology, 2017
Erdinc Sezgin, Ilya Levental, Satyajit Mayor   +2 more
exaly   +2 more sources

α1-nAchR-Mediated Signaling Through Lipid Raft Is Required for Nicotine-Induced NLRP3 Inflammasome Activation and Nicotine-Accelerated Atherosclerosis

Frontiers in Cell and Developmental Biology, 2021
BackgroundNicotine exerts direct effects on multiple cell types in the cardiovascular system by associating with its high-affinity nicotinic acetylcholine receptors (nAchRs).
Fengqi Duan, Cheng Zeng, Sijun Liu, Jianfeng Gong, Jia Hu, Hongyu Li, Hongmei Tan, Hongmei Tan, Hongmei Tan   +8 more
doaj   +1 more source

Cold induces micro- and nano-scale reorganization of lipid raft markers at mounds of T-cell membrane fluctuations. [PDF]

PLoS ONE, 2009
Whether and how cold causes changes in cell-membrane or lipid rafts remain poorly characterized. Using the NSOM/QD and confocal imaging systems, we found that cold caused microscale redistribution of lipid raft markers, GM1 for lipid and CD59 for protein,
Yong Chen, Jie Qin, Jiye Cai, Zheng W Chen   +3 more
doaj   +1 more source

Role of membrane microdomains in compartmentation of cAMP signaling. [PDF]

PLoS ONE, 2014
Spatially restricting cAMP production to discrete subcellular locations permits selective regulation of specific functional responses. But exactly where and how cAMP signaling is confined is not fully understood.
Shailesh R Agarwal, Pei-Chi Yang, Monica Rice, Cherie A Singer, Viacheslav O Nikolaev, Martin J Lohse, Colleen E Clancy, Robert D Harvey   +7 more
doaj   +1 more source

Generation of stable lipid raft microdomains in the enterocyte brush border by selective endocytic removal of non-raft membrane. [PDF]

PLoS ONE, 2013
The small intestinal brush border has an unusually high proportion of glycolipids which promote the formation of lipid raft microdomains, stabilized by various cross-linking lectins. This unique membrane organization acts to provide physical and chemical
E Michael Danielsen, Gert H Hansen
doaj   +1 more source

Comprehensive bioinformatic analyses of KRAS mutations and deciphering chromatin modification landscape of Caveolin-1 gene by lipid raft destabilization induced modulation of RAS-MAPK axis in colon cancer

Advances in Cancer Biology - Metastasis, 2022
Ras signaling contributes to multiple components of cellular functions. To gain insight into the role of KRAS mutant isoforms, we bioinformatically analyzed and noticed that KRAS mutations at G12V, G12D, and G13D positions are prominent in colorectal ...
Ankan Roy, Moonmoon Deb, Niharika, Sabnam Parbin, Arunima Shilpi, Samir Kumar Patra   +5 more
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UL11 Protein Is a Key Participant of the Duck Plague Virus in Its Life Cycle

Frontiers in Microbiology, 2022
Tegument protein UL11 plays a critical role in the life cycle of herpesviruses. The UL11 protein of herpesviruses is important for viral particle entry, release, assembly, and secondary envelopment.
Linjiang Yang, Linjiang Yang, Linjiang Yang, Mingshu Wang, Mingshu Wang, Mingshu Wang, Anchun Cheng, Anchun Cheng, Anchun Cheng, Qiao Yang, Qiao Yang, Qiao Yang, Ying Wu, Ying Wu, Ying Wu, Juan Huang, Juan Huang, Juan Huang, Bin Tian, Bin Tian, Renyong Jia, Renyong Jia, Renyong Jia, Mafeng Liu, Mafeng Liu, Mafeng Liu, Dekang Zhu, Dekang Zhu, Shun Chen, Shun Chen, Shun Chen, Xinxin Zhao, Xinxin Zhao, Xinxin Zhao, Shaqiu Zhang, Shaqiu Zhang, Shaqiu Zhang, Xumin Ou, Xumin Ou, Xumin Ou, Sai Mao, Sai Mao, Sai Mao, Qun Gao, Qun Gao, Qun Gao, Di Sun, Di Sun, Di Sun, Yanlin Yu, Yanlin Yu, Yanlin Yu, Ling Zhang, Ling Zhang, Ling Zhang   +54 more
doaj   +1 more source