Results 221 to 230 of about 63,616 (299)

The multifaceted roles of the ACSL family in cancer: Metabolic reprogramming, ferroptosis regulation and tumour immune microenvironment remodelling

Clinical and Translational Medicine, Volume 16, Issue 3, March 2026.
The acyl‐CoA synthetase long‐chain (ACSL) family consists of five members, which exhibit a synergistic effect in promoting tumour lipid metabolism for energy supply. Specifically, ACSL3 and ACSL4 have antagonistic effects on the mechanisms related to ferroptosis in tumour cells.
Haocai Li, Weijian Wang, Juncheng Zhan, Yuxiang Xiao, Xiaoping Chen, Chen Su, Peng Zhu   +6 more
wiley   +1 more source

Critical micellar concentration determination of pure phospholipids and lipid-raft and their mixtures with cholesterol. [PDF]

Proteins
Serravalle S, Pisano M, Sciacca MFM, Salamone N, Sicali L, Mazzara G, Costa L, La Rosa C.   +7 more
europepmc   +1 more source

Ninjurin1 in cardiovascular and vascular biology: From molecular mechanisms to therapeutic opportunities

Clinical and Translational Medicine, Volume 16, Issue 3, March 2026.
NINJ1 mediates PMR in cardiovascular cell death, releasing DAMPs that amplify vascular inflammation. Dual NINJ1 paradox: membrane‐bound form drives endothelial NF‐κB/CXCL‐8 inflammation while soluble form provides atheroprotection. Pericyte NINJ1 regulates the critical balance between angiogenic sprouting and vessel maturation in ischaemic tissues ...
Muhammad Mamunur Rashid Mahib
wiley   +1 more source

A Patching and Coding Lipid Raft-Localized Universal Imaging Platform. [PDF]

Chem Biomed Imaging
Zhong T, Chen Y, Yan X, Li Y, Wang H, Zhong Y, Li K, Xie R, Dong H, Ding L, Ju H.   +10 more
europepmc   +1 more source

Transcriptome–Proteome Analysis of Human Naive and Memory B Cell Subsets Reveals Isotype and Subclass‐Specific Phenotypes

European Journal of Immunology, Volume 56, Issue 3, March 2026.
We performed combined proteome and transcriptome analysis of human isotype‐defined B cell subsets. IgG4‐switched B cells were most distinct from naive B cells in terms of mRNA as well as protein expression profiles. SDR16C5 was identified as uniquely upregulated in IgG4‐switched B cells.
Jana Koers, Arie J. Hoogendijk, Simon Tol, Floris P.J. Van Alphen, Ninotska I.L. Derksen, Maartje van den Biggelaar, Theo Rispens   +6 more
wiley   +1 more source

Characterization and Fluctuations of an Ivermectin Binding Site at the Lipid Raft Interface of the N-Terminal Domain (NTD) of the Spike Protein of SARS-CoV-2 Variants. [PDF]

Viruses
Lefebvre M, Chahinian H, La Scola B, Fantini J.   +3 more
europepmc   +1 more source

Human Milk–Derived Peptide MAMP‐1 Ameliorates Sepsis‐Associated Acute Lung Injury in Mice Through APOA4 and the TLR4/NF‐κB Signaling Pathway

Food Frontiers, Volume 7, Issue 2, March 2026.
The study found that MAMP‐1 can alleviate lung injury by modulating the TLR4 signaling pathway to suppress LPS‐induced inflammation and promote cholesterol reverse transport. ABSTRACT Sepsis‐associated acute lung injury (SALI) significantly jeopardizes the health and survival prospects of neonates.
Shimei Lu, Rui Long, Yanmin Li, Fengqiong Tan, Xiaoguang He, Tengfei Wang, Xingyun Wang, Fengdan Xu, Ning Li   +8 more
wiley   +1 more source

Expression of Concern for Interfering with Lipid Raft Association: A Mechanism to Control Influenza Virus Infection By Sambucus nigra [Iran J Pharm Res. 2017; 16 (3): e124953]. [PDF]

Iran J Pharm Res
Ijpr EI.
europepmc   +1 more source

Molecular imprinting for neurology: Materials, applications, and limitations

Ibrain, Volume 12, Issue 1, Page 3-37, Spring 2026.
Molecularly imprinted materials: diagnostic, therapeutic and research applications in neurology. Molecularly imprinted materials offer high specificity and affinity for target molecules in neurological applications. This review highlights their synthesis, characterisation, and use in diagnostics, research and therapeutics.
Xiaohan Ma, Yingqi Ma, Claudia Marino, Alessandro Poma   +3 more
wiley   +1 more source

PIEZO1 Channels Modulate the Small Extracellular Vesicle Release in C2C12 Cells

Journal of Cellular Physiology, Volume 241, Issue 3, March 2026.
ABSTRACT PIEZO1 are mechanically‐activated ion channels expressed in many cell types. Their pharmacological activation by the selective agonist Yoda1 has been reported to favor skeletal muscle regeneration by controlling the fate of myogenic precursors cells, but the underlying mechanisms remain largely unknown.
Bernareggi Annalisa, Zhang Wen Ru, Sanchez‐Sanchez Laura, Norbedo Alessia, Fracassi Anna, Lucafò Marianna, Sciancalepore Marina, Alberto Griffoni, Russell K. William, Taglialatela Giulio, Lorenzon Paola, Limon Agenor   +11 more
wiley   +1 more source