Results 221 to 230 of about 1,129,041 (391)

Epileptiform activity influences theta-burst induced LTP in the adult hippocampus: a role for synaptic lipid raft disruption in early metaplasticity? [PDF]

Front Cell Neurosci, 2023
Carvalho-Rosa JD, Rodrigues NC, Silva-Cruz A, Vaz SH, Cunha-Reis D.   +4 more
europepmc   +1 more source

Cationic‐Hydrophilic Di‐Block Copolymers: Surface‐Shielded Vectors for Gene Delivery

Journal of Polymer Science, Volume 63, Issue 6, Page 1419-1432, 15 March 2025.
This study develops synthetic polycationic di‐block carriers for nucleic acid (NA) delivery in gene therapy. Consisting of a cationic block and a hydrophilic block, these carriers efficiently form complexes with NAs and shield them with a protective bioinert layer, enhancing stability during circulation in the bloodstream while reducing undesirable ...
Eliška Hrdá, Ladislav Androvič, Marcela Filipová, Michal Pechar, Richard Laga   +4 more
wiley   +1 more source

Membrane Lipid Domains Distinct from Cholesterol/Sphingomyelin-Rich Rafts Are Involved in the ABCA1-mediated Lipid Secretory Pathway [PDF]

, 2001
Armando J. Mendez, Guorong Lin, David P. Wade, Richard M. Lawn, John F. Oram   +4 more
openalex   +1 more source

Lipid rafts and raft-mediated supramolecular entities in the regulation of CD95 death receptor apoptotic signaling

Apoptosis, 2015
C. Gajate, F. Mollinedo
semanticscholar   +1 more source

The serine palmitoyl transferase of plant pathogenic fungi: a promising new target for the development of novel crop protection solutions†

Pest Management Science, EarlyView.
High biological activity of pyridazine carboxamides against a wide range of Ascomycetes led to identification of a new biochemical target for agrochemical fungicides – serine palmitoyl transferase. Abstract BACKGROUND Plant pathogens pose a significant threat to global agriculture and, thus to world food supplies, requiring the development of ...
Lionel Nicolas, Emilia Hilz, Stephanie Gamet, Vincent Thomas, Stephane Peyrard, Luigi Di Vietro, Benedicte Cirer, Julie Geist, Bernd Essigmann, Anne Ferry, Angeline Chanel, Frédéric Berniaud, Dominik Schwarz, Virginie Lempereur   +13 more
wiley   +1 more source

AIBP regulates TRPV1 activation in chemotherapy-induced peripheral neuropathy by controlling lipid raft dynamics and proximity to TLR4 in dorsal root ganglion neurons. [PDF]

Pain, 2023
Navia-Pelaez JM, Borges Paes Lemes J, Gonzalez L, Delay L, Dos Santos Aggum Capettini L, Lu JW, Gonçalves Dos Santos G, Gregus AM, Dougherty PM, Yaksh TL, Miller YI.   +10 more
europepmc   +1 more source

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

Small, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti, Marius F.W. Trollmann, Christina Wichmann, Thomas Gutsmann, Christian Eggeling, Rainer A. Böckmann   +5 more
wiley   +1 more source

The prohibitin complex regulates macrophage fatty acid composition, plasma membrane packing, and lipid raft-mediated inflammatory signaling. [PDF]

Prostaglandins Leukot Essent Fatty Acids, 2023
Matthews CEP, Fussner LA, Yaeger M, Aloor JJ, Reece SW, Kilburg-Basnyat BJ, Varikuti S, Luo B, Inks M, Sergin S, Schmidt CA, Neufer PD, Pennington ER, Fisher-Wellman KH, Chowdhury SM, Fessler MB, Fenton JI, Anderson EJ, Shaikh SR, Gowdy KM.   +19 more
europepmc   +1 more source

Cyclodextrin‐Based Pseudocopolymers and Their Biomedical Applications for Drug and Gene Delivery

Small, EarlyView.
Host–guest interactions between cyclodextrin (CD) and compatible guest molecules enable the formation of diverse architectures, such as multiblock and linear–star copolymers as well as advanced systems like redox‐responsive nanoparticles. This structural versatility facilitates precise system design, conferring multifunctionality for controlled drug ...
Wilson Wee Mia Soh, Jun Li
wiley   +1 more source

Membrane lipid raft homeostasis is directly linked to neurodegeneration. [PDF]

Essays Biochem, 2021
Moll T, Marshall JNG, Soni N, Zhang S, Cooper-Knock J, Shaw PJ, Shaw PJ.   +6 more
europepmc   +1 more source