Results 21 to 30 of about 69,365 (334)
Cold induces micro- and nano-scale reorganization of lipid raft markers at mounds of T-cell membrane fluctuations. [PDF]
PLoS ONE, 2009 Whether and how cold causes changes in cell-membrane or lipid rafts remain poorly characterized. Using the NSOM/QD and confocal imaging systems, we found that cold caused microscale redistribution of lipid raft markers, GM1 for lipid and CD59 for protein,
Yong Chen +3 more
doaj +1 more source
Interaction of drugs with lipid raft membrane domains as a possible target
Drug Target Insights, 2020 Introduction: Plasma membranes are not the homogeneous bilayers of uniformly distributed lipids but the lipid complex with laterally separated lipid raft membrane domains, which provide receptor, ion channel and enzyme proteins with a platform.
Hironori Tsuchiya, Maki Mizogami
doaj +1 more source
Role of membrane microdomains in compartmentation of cAMP signaling. [PDF]
PLoS ONE, 2014 Spatially restricting cAMP production to discrete subcellular locations permits selective regulation of specific functional responses. But exactly where and how cAMP signaling is confined is not fully understood.
Shailesh R Agarwal +7 more
doaj +1 more source
Generation of stable lipid raft microdomains in the enterocyte brush border by selective endocytic removal of non-raft membrane. [PDF]
PLoS ONE, 2013 The small intestinal brush border has an unusually high proportion of glycolipids which promote the formation of lipid raft microdomains, stabilized by various cross-linking lectins. This unique membrane organization acts to provide physical and chemical
E Michael Danielsen, Gert H Hansen
doaj +1 more source
Advances in Cancer Biology - Metastasis, 2022 Ras signaling contributes to multiple components of cellular functions. To gain insight into the role of KRAS mutant isoforms, we bioinformatically analyzed and noticed that KRAS mutations at G12V, G12D, and G13D positions are prominent in colorectal ...
Ankan Roy +5 more
doaj +1 more source
UL11 Protein Is a Key Participant of the Duck Plague Virus in Its Life Cycle
Frontiers in Microbiology, 2022 Tegument protein UL11 plays a critical role in the life cycle of herpesviruses. The UL11 protein of herpesviruses is important for viral particle entry, release, assembly, and secondary envelopment.
Linjiang Yang +54 more
doaj +1 more source
Lipid raft microdomain compartmentalization of TC10 is required for insulin signaling and GLUT4 translocation. [PDF]
, 2001 Recent studies indicate that insulin stimulation of glucose transporter (GLUT)4 translocation requires at least two distinct insulin receptor-mediated signals: one leading to the activation of phosphatidylinositol 3 (PI-3) kinase and the other to the ...
Chiang, SH +7 more
core +3 more sources
Frontiers in Cell and Developmental Biology, 2021 Chemosensitization of cancer cells with small molecules may improve the therapeutic index of antitumoral agents by making tumor cells sensitive to the drug regimen and thus overcome the treatment resistance and side effects of single therapy.
Siddhartha Kumar Mishra +7 more
doaj +1 more source
, 1968 Acute cholesterol depletion is generally associated with decreased or abolished T cell signalling but it can also cause T cell activation. This anomaly has been addressed in Jurkat T cells using progressive cholesterol depletion with methyl-beta ...
Adler, Jeremy +3 more
core +2 more sources
Alterations of membrane curvature during influenza virus budding [PDF]
, 2014 Influenza A virus belongs to the Orthomyxoviridae family. It is an enveloped virus that contains a segmented and negative-sense RNA genome. Influenza A viruses cause annual epidemics and occasional major pandemics, are a major cause of morbidity and ...
Agnieszka Martyna +29 more
core +1 more source