Results 31 to 40 of about 1,129,041 (391)
Lipids in the brain are major components playing structural functions as well as physiological roles in nerve cells, such as neural communication, neurogenesis, synaptic transmission, signal transduction, membrane compartmentalization, and regulation of ...
Fátima Mesa-Herrera+4 more
semanticscholar +1 more source
The Lipid Raft Proteome of African Trypanosomes Contains Many Flagellar Proteins
Lipid rafts are liquid-ordered membrane microdomains that form by preferential association of 3-β-hydroxysterols, sphingolipids and raft-associated proteins often having acyl modifications.
Aabha I. Sharma+2 more
doaj +1 more source
The specialized cholesterol/sphingolipid-rich membrane domains termed lipid rafts are highly dynamic in the cancer cells, which rapidly assemble effector molecules to form a sorting platform essential for oncogenic signaling transduction in response to ...
Tsung-Lin Lee+6 more
doaj +1 more source
Mild Heat Treatment Primes Human CD34(+) Cord Blood Cells for Migration Toward SDF-1α and Enhances Engraftment in an NSG Mouse Model [PDF]
Simple efforts are needed to enhance cord blood (CB) transplantation. We hypothesized that short-term exposure of CD34(+) CB cells to 39.5°C would enhance their response to stromal-derived factor-1 (SDF-1), by increasing lipid raft aggregation and CXCR4 ...
Broxmeyer, Hal E.+3 more
core +1 more source
Cholesterol, lipid rafts, and disease [PDF]
Lipid rafts are dynamic assemblies of proteins and lipids that float freely within the liquid-disordered bilayer of cellular membranes but can also cluster to form larger, ordered platforms. Rafts are receiving increasing attention as devices that regulate membrane function in eukaryotic cells.
Kai Simons, Robert Ehehalt
openaire +2 more sources
Current thinking on lipid membrane organization has evolved from the seminal fluid mosaic model proposed by [Singer and Nicolson (1972)][1]. Subsequent studies on plasma membranes suggest that biological membranes are not a simple homogeneous layer of proteins and lipids, but rather are ...
openaire +3 more sources
Lipid Rafts and Plant Gravisensitivity
The necessity to include plants as a component of a Bioregenerative Life Support System leads to investigations to optimize plant growth facilities as well as a better understanding of the plant cell membrane and its numerous activities in the signaling, transport, and sensing of gravity, drought, and other stressors.
Elizabeth L. Kordyum+2 more
openaire +3 more sources
Lipid21: Complex Lipid Membrane Simulations with AMBER
We extend the modular AMBER lipid force field to include anionic lipids, polyunsaturated fatty acid (PUFA) lipids, and sphingomyelin, allowing the simulation of realistic cell membrane lipid compositions, including raft-like domains.
Callum J. Dickson, R. Walker, I. Gould
semanticscholar +1 more source
Lipid rafts are highly ordered regions of the plasma membrane that are enriched in cholesterol and sphingolipids and play important roles in many cells.
Pooranee K. Morgan+3 more
doaj +1 more source
Of Rafts and Lipid Chain Lengths [PDF]
Plasma membranes are believed to be highly heterogeneous, and to contain coexisting liquid-ordered domains (known as rafts), which are enriched in cholesterol and sphingomyelin, and liquid-disordered domains. Similar heterogeneities exist in synthetic membrane systems. Previous studies of asymmetric lipid bilayers have demonstrated that the presence of
Anne Hinderliter, Kalina Hristova
openaire +3 more sources