Results 31 to 40 of about 1,129,041 (391)

Lipid and Lipid Raft Alteration in Aging and Neurodegenerative Diseases: A Window for the Development of New Biomarkers

open access: yesInternational Journal of Molecular Sciences, 2019
Lipids in the brain are major components playing structural functions as well as physiological roles in nerve cells, such as neural communication, neurogenesis, synaptic transmission, signal transduction, membrane compartmentalization, and regulation of ...
Fátima Mesa-Herrera   +4 more
semanticscholar   +1 more source

The Lipid Raft Proteome of African Trypanosomes Contains Many Flagellar Proteins

open access: yesPathogens, 2017
Lipid rafts are liquid-ordered membrane microdomains that form by preferential association of 3-β-hydroxysterols, sphingolipids and raft-associated proteins often having acyl modifications.
Aabha I. Sharma   +2 more
doaj   +1 more source

Impairment of Membrane Lipid Homeostasis by Bichalcone Analog TSWU-BR4 Attenuates Function of GRP78 in Regulation of the Oxidative Balance and Invasion of Cancer Cells

open access: yesCells, 2020
The specialized cholesterol/sphingolipid-rich membrane domains termed lipid rafts are highly dynamic in the cancer cells, which rapidly assemble effector molecules to form a sorting platform essential for oncogenic signaling transduction in response to ...
Tsung-Lin Lee   +6 more
doaj   +1 more source

Mild Heat Treatment Primes Human CD34(+) Cord Blood Cells for Migration Toward SDF-1α and Enhances Engraftment in an NSG Mouse Model [PDF]

open access: yes, 2015
Simple efforts are needed to enhance cord blood (CB) transplantation. We hypothesized that short-term exposure of CD34(+) CB cells to 39.5°C would enhance their response to stromal-derived factor-1 (SDF-1), by increasing lipid raft aggregation and CXCR4 ...
Broxmeyer, Hal E.   +3 more
core   +1 more source

Cholesterol, lipid rafts, and disease [PDF]

open access: yesJournal of Clinical Investigation, 2002
Lipid rafts are dynamic assemblies of proteins and lipids that float freely within the liquid-disordered bilayer of cellular membranes but can also cluster to form larger, ordered platforms. Rafts are receiving increasing attention as devices that regulate membrane function in eukaryotic cells.
Kai Simons, Robert Ehehalt
openaire   +2 more sources

Lipid Rafts in Plants [PDF]

open access: yesPlant Physiology, 2007
Current thinking on lipid membrane organization has evolved from the seminal fluid mosaic model proposed by [Singer and Nicolson (1972)][1]. Subsequent studies on plasma membranes suggest that biological membranes are not a simple homogeneous layer of proteins and lipids, but rather are ...
openaire   +3 more sources

Lipid Rafts and Plant Gravisensitivity

open access: yesLife, 2022
The necessity to include plants as a component of a Bioregenerative Life Support System leads to investigations to optimize plant growth facilities as well as a better understanding of the plant cell membrane and its numerous activities in the signaling, transport, and sensing of gravity, drought, and other stressors.
Elizabeth L. Kordyum   +2 more
openaire   +3 more sources

Lipid21: Complex Lipid Membrane Simulations with AMBER

open access: yesJournal of Chemical Theory and Computation, 2022
We extend the modular AMBER lipid force field to include anionic lipids, polyunsaturated fatty acid (PUFA) lipids, and sphingomyelin, allowing the simulation of realistic cell membrane lipid compositions, including raft-like domains.
Callum J. Dickson, R. Walker, I. Gould
semanticscholar   +1 more source

Hematopoiesis is regulated by cholesterol efflux pathways and lipid rafts: connections with cardiovascular diseases

open access: yesJournal of Lipid Research, 2020
Lipid rafts are highly ordered regions of the plasma membrane that are enriched in cholesterol and sphingolipids and play important roles in many cells.
Pooranee K. Morgan   +3 more
doaj   +1 more source

Of Rafts and Lipid Chain Lengths [PDF]

open access: yesBiophysical Journal, 2015
Plasma membranes are believed to be highly heterogeneous, and to contain coexisting liquid-ordered domains (known as rafts), which are enriched in cholesterol and sphingomyelin, and liquid-disordered domains. Similar heterogeneities exist in synthetic membrane systems. Previous studies of asymmetric lipid bilayers have demonstrated that the presence of
Anne Hinderliter, Kalina Hristova
openaire   +3 more sources

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