Results 51 to 60 of about 1,129,041 (391)
A lifeline for lipid rafts? [PDF]
Journal of Cell Biology, 2013 Study finds raft-like domains in yeast vacuole membrane.
openaire +2 more sources
Proteome Science, 2007 Background The low concentration and highly hydrophobic nature of proteins in lipid raft samples present significant challenges for the sensitive and accurate proteomic analyses of lipid raft proteins.
Tint G Stephen +5 more
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Aggregation of lipid rafts activates c-met and c-Src in non-small cell lung cancer cells
BMC Cancer, 2018 Background Activation of c-Met, a receptor tyrosine kinase, induces radiation therapy resistance in non-small cell lung cancer (NSCLC). The activated residual of c-Met is located in lipid rafts (Duhon et al. Mol Carcinog 49:739-49, 2010).
Juan Zeng +6 more
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Flagellar membrane association via interaction with lipid rafts [PDF]
, 2009 The eukaryotic flagellar membrane has a distinct composition from other domains of the plasmalemma. Our work shows that the specialized composition of the trypanosome flagellar membrane reflects increased concentrations of sterols and saturated fatty ...
Cieslak, John A. +6 more
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Evidence for the involvement of lipid rafts localized at the ER-mitochondria associated membranes in autophagosome formation [PDF]
, 2016 Mitochondria-associated membranes (MAMs) are subdomains of the endoplasmic reticulum (ER) that interact with mitochondria. This membrane scrambling between ER and mitochondria appears to play a critical role in the earliest steps of autophagy.
Faggioni, Alberto +9 more
core +2 more sources
Lipid Raft-Mediated Regulation of Hyaluronan–CD44 Interactions in Inflammation and Cancer
Frontiers in Immunology, 2015 Hyaluronan is a major component of the extracellular matrix and plays pivotal roles in inflammation and cancer. Hyaluronan oligomers are frequently found in these pathological conditions, in which they exert their effects via association with the ...
T. Murai
semanticscholar +1 more source
Phosphorylation of CLEC-2 is dependent on lipid rafts, actin polymerization,secondary mediators, and Rac [PDF]
, 2010 The C-type lectin-like receptor 2 (CLEC-2)activates platelets through Src and Syk tyrosine kinases via a single cytoplasmic YxxL motif known as a hem immunoreceptor tyrosine-based activation motif (hemITAM).Here, we demonstrate using sucrose gradient ...
Alice Y. Pollitt +44 more
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Lipid Raft is required for PSGL-1 ligation induced HL-60 cell adhesion on ICAM-1. [PDF]
PLoS ONE, 2013 P-selectin glycoprotein ligand-1 (PSGL-1) and integrins are adhesion molecules that play critical roles in host defense and innate immunity. PSGL-1 mediates leukocyte rolling and primes leukocytes for integrin-mediated adhesion.
Tingshuang Xu +8 more
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The Many Faces of Lipid Rafts [PDF]
Biophysical Journal, 2014 Recent experimental observations in raft-forming lipid bilayers demonstrated a phase behavior unsuspected just a few years ago (1,2). Mixtures of Chol (cholesterol) with disordered (unsaturated) and ordered (saturated) phospholipids change their phase behavior from apparently uniform phases to modulated phases to complete phase separation by small ...
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Monolayer curvature stabilizes nanoscale raft domains in mixed lipid bilayers [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2013 According to the lipid raft hypothesis, biological lipid membranes are laterally heterogeneous and filled with nanoscale ordered “raft” domains, which are believed to play an important role for the organization of proteins in membranes.
Sebastian Meinhardt, R. Vink, F. Schmid
semanticscholar +1 more source