Inflammation and lipid signaling in the etiology of insulin resistance.
Cell Metabolism, 2012 C. Glass, J. Olefsky
semanticscholar +1 more source
The effects of protease inhibitors on basal and insulin-stimulated lipid metabolism, insulin binding, and signaling [PDF]
, 2003 Catarina Cammalleri, Ralph J. Germinario
openalex +1 more source
Advanced Functional Materials, EarlyView.Many known diseases arise from dysregulated gene expression, and differentially expressed genes can serve as biomarkers to distinguish diseased cells from healthy tissues. In this study, reconfigurable nucleic acid nanoparticles (recNANPs) are introduced that can detect overexpressed cancer biomarkers and subsequently release RNAi inducers to silence ...
Yelixza I. Avila +7 more
wiley +1 more source
Lipid transfer proteins and instructive regulation of lipid kinase activities: Implications for inositol lipid signaling and disease. [PDF]
Adv Biol Regul, 2020 Lete MG +4 more
europepmc +1 more source
Visualizing Lipid Raft Dynamics and Early Signaling Events during Antigen Receptor-mediated B-Lymphocyte Activation [PDF]
, 2003 Neetu Gupta, Anthony DeFranco
openalex +1 more source
Advanced Functional Materials, EarlyView.Zr‐Fe MOF@Ribociclib@Herceptin (ZFRH) efficiently targets/kills Human Epidermal Growth Factor Receptor 2/Estrogen Receptor‐positive (HER2/ER+) breast cancer cells. It combats tumors by: 1) Elevating ROS, altering redox balance; 2) Inhibiting transcription; 3) Inducing pyroptosis.
Hongkun Miao +8 more
wiley +1 more source
AMPK-Dependent Mechanisms but Not Hypothalamic Lipid Signaling Mediates GH-Secretory Responses to GHRH and Ghrelin. [PDF]
Cells, 2020 Vázquez MJ +8 more
europepmc +1 more source
Lipid Rafts Unite Signaling Cascades with Clathrin to Regulate BCR Internalization
, 2002 Angela Stoddart +5 more
openalex +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, EarlyView.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Harnessing lipid signaling pathways to target specialized pro-angiogenic neutrophil subsets for regenerative immunotherapy. [PDF]
Sci Adv, 2020 Turner TC +10 more
europepmc +1 more source