Results 261 to 270 of about 1,963,371 (292)

Inositol lipids in cell signalling

Current Biology, 1992
In the past year, major advances have been made in our understanding of the regulation of phosphoinositidase C, and of the action of the inositol trisphosphate receptor and how it may generate 'quantal' Ca2+ release. The functions of inositol tetrakisphosphate and of the 3-phosphorylated inositol lipids continue to generate controversy, but both may be
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Lipid signaling in pathogenic fungi

Current Opinion in Microbiology, 2006
Recent studies have highlighted the importance of lipid signaling molecules in the development and pathogenicity of clinically important fungi. In Cryptococcus neoformans, sphingolipid-derived diacylglycerol has been shown to induce the transcription of the putative virulence factor App1, which inhibits the phagocytosis of fungal cells by alveolar ...
John M, Shea, Maurizio, Del Poeta
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Lipid Signaling in Experimental Epilepsy

Neurochemical Research, 2005
Glutamate release activates signaling pathways important for learning and memory, and over-stimulation of these pathways during seizures leads to aberrant synaptic plasticity associated with hyper-excitable, seizure-prone states. Seizures induce rapid accumulation of membrane lipid-derived fatty acids at the synapses which, evidence suggests, regulate ...
Kasie K, Cole-Edwards, Nicolas G, Bazan
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Lipids and Lipid-Mediated Signaling in Plant–Pathogen Interactions

International Journal of Molecular Sciences
Plant lipids are essential cell constituents with many structural, storage, signaling, and defensive functions. During plant–pathogen interactions, lipids play parts in both the preexisting passive defense mechanisms and the pathogen-induced immune responses at the local and systemic levels.
Ewa Gajewska, Elżbieta Kuźniak-Gębarowska   +1 more
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Lipidic Signaling and Peroxisomal Function

1998
While the important role of lipids in relation to cellular signaling is firmly established and in general well reviewed (Exton, 1994; Barrett, 1992), several novel aspects of the subject have only recently come to light, which involve peroxisomal function, and which appear deserving of further commentary.
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Protein Lipidation in Cell Signaling

Science, 1995
The ability of cells to communicate with and respond to their external environment is critical for their continued existence. A universal feature of this communication is that the external signal must in some way penetrate the lipid bilayer surrounding the cell.
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Lipid signaling in the atherogenesis context

Biochemistry (Moscow), 2010
Normally macrophages localized in the arterial vessel wall perform the "reverse transfer" of cholesterol, which includes endocytosis of low density lipoproteins (LDL), cholesterol transfer to newly formed high density lipoprotein particles, and their following elimination by the liver.
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Focus Issue: Signaling Lipids

Science's STKE, 2006
Membranes are dynamic and specific contributors to cell signaling. Cellular membranes play a key structural role in creating sites for the formation of signaling complexes. Changes in membrane phospholipids can regulate the activity of transmembrane and peripheral membrane proteins.
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Lipid Metabolism, Lipid Signalling and Longevity

2016
Ageing research gains more attention as the aged population increases worldwide and ageing-related diseases become more prevalent. Model organism research in the last three decades has shown that ageing is regulated via several genetic pathways and environmental interventions, most of which are evolutionarily conserved. C.
Jonathon Duffy, Ayse Sena Mutlu, Meng C. Wang   +2 more
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Nuclear Lipid Metabolism and Signaling

Journal of Biochemistry, 2002
Evidence has been accumulating that nuclear lipid metabolism is involved in the regulation of nuclear functions. Here I describe an autonomous nuclear lipid signaling that has been found to be associated with the metabolism of such lipids as phosphoinositides, choline phospholipids, and the acylation and deacylation cycle.
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