Results 41 to 50 of about 41,885 (269)

Lipidomic, Transcriptomic, and BSA-660K Single Nucleotide Polymorphisms Profiling Reveal Characteristics of the Cuticular Wax in Wheat

open access: yesFrontiers in Plant Science, 2021
Plant epidermal wax helps protect plants from adverse environmental conditions, maintains the function of tissues and organs, and ensures normal plant development.
Jun Zheng   +7 more
doaj   +1 more source

A Metabolomic Profiling of Intra-Uterine Growth Restriction in Placenta and Cord Blood Points to an Impairment of Lipid and Energetic Metabolism

open access: yesBiomedicines, 2022
(1) Background: Intrauterine growth restriction (IUGR) involves metabolic changes that may be responsible for an increased risk of metabolic and cardiovascular diseases in adulthood.
Juan Manuel Chao de la Barca   +9 more
doaj   +1 more source

Cyclocarya paliurus Leaves Tea Improves Dyslipidemia in Diabetic Mice: A Lipidomics-Based Network Pharmacology Study

open access: yesFrontiers in Pharmacology, 2018
Hyperlipidemia and hepatic steatosis afflict over 75% of patients with type 2 diabetes, causing diabetic dyslipidemia. Cyclocarya paliurus (CP) leaf is a herbal tea which has long been consumed by the Chinese population, particularly people suffering ...
Lixiang Zhai   +10 more
doaj   +1 more source

The patatin-like phospholipase PfPNPLA2 is involved in the mitochondrial degradation of phosphatidylglycerol during Plasmodium falciparum blood stage development

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
Plasmodium falciparum is an Apicomplexa responsible for human malaria, a major disease causing more than ½ million deaths every year, against which there is no fully efficient vaccine.
Serena Shunmugam   +8 more
doaj   +1 more source

Open field study of some Zea mays hybrids, lipid compounds and fumonisins accumulation [PDF]

open access: yes, 2015
Lipid molecules are increasingly recognized as signals exchanged by organisms interacting in pathogenic and/or symbiotic ways. Some classes of lipids actively determine the fate of the interactions.
Battilani, Paola   +8 more
core   +2 more sources

Lipid droplets and lipotoxicity during autophagy. [PDF]

open access: yes, 2017
Lipid droplets (LDs) are neutral lipid storage organelles that provide a rapidly accessible source of fatty acids (FAs) for energy during periods of nutrient deprivation.
Nguyen, Truc, Olzmann, James
core   +2 more sources

Applying metabolomics to cardiometabolic intervention studies and trials: past experiences and a roadmap for the future [PDF]

open access: yes, 2016
Metabolomics and lipidomics are emerging methods for detailed phenotyping of small molecules in samples. It is hoped that such data will: (i) enhance baseline prediction of patient response to pharmacotherapies (beneficial or adverse); (ii) reveal ...
Preiss, David   +3 more
core   +2 more sources

Neuronal human BACE1 knock-in induces systemic diabetes in mice [PDF]

open access: yes, 2016
Acknowledgements The authors thank S. Tammireddy (Diabetes and Cardiovascular Science, University of the Highlands and Islands, Inverness, UK) for technical support with the lipidomics component. Funding We would like to thank R.
Dekeryte, Ruta   +12 more
core   +4 more sources

Advances in lipidomics [PDF]

open access: yesClinica Chimica Acta, 2020
The present article examines recently published literature on lipids, mainly focusing on research involving glycero-, glycerophospho- and sphingo-lipids. The primary aim is identification of distinct profiles in biologic lipidomic systems by ultra-high-performance liquid chromatography (UHPLC) coupled with mass spectrometry (MS, tandem MS) with ...
Henri F. Avela, Heli Sirén
openaire   +2 more sources

Cell-specific discrimination of desmosterol and desmosterol mimetics confers selective regulation of LXR and SREBP in macrophages. [PDF]

open access: yes, 2018
Activation of liver X receptors (LXRs) with synthetic agonists promotes reverse cholesterol transport and protects against atherosclerosis in mouse models.
Bahadorani, John   +16 more
core   +1 more source

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