Results 101 to 110 of about 47,866 (282)

Mechanical unloading is accompanied by reverse metabolic remodelling in the failing heart: Identification of a novel citraconate‐mediated pathway

open access: yesEuropean Journal of Heart Failure, EarlyView.
Aims Although functional recovery of the failing heart with left ventricular assist device (LVAD) unloading can occur, the underpinning mechanism is unclear. We aimed to characterize the effect of myocardial biochemical effect of LVAD support in vivo and in vitro.
David M. Kaye   +15 more
wiley   +1 more source

Enhanced Separation of Extracellular Vesicles Using Capillary Isotachophoresis With Spacer Compounds

open access: yesELECTROPHORESIS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are pivotal in numerous physiological and pathological processes, such as immune responses, viral pathogenesis, pregnancy, cardiovascular diseases, and cancer progression. Their capacity to influence complex intracellular pathways highlights their therapeutic potential in addressing various conditions, including ...
Milan Pieter Paul de Putter   +4 more
wiley   +1 more source

Lipidomics of cellular and secreted phospholipids from differentiated human fetal type II alveolar epithelial cells [PDF]

open access: hybrid, 2006
Anthony D. Postle   +6 more
openalex   +1 more source

Lipidome and disease [PDF]

open access: yesFEBS Letters, 2006
Helms, J.B., van Meer, G.
openaire   +3 more sources

A protective role for N-acylphosphatidylethanolamine phospholipase D in 6-OHDA-induced neurodegeneration. [PDF]

open access: yes, 2019
N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) catalyzes the cleavage of membrane NAPEs into bioactive fatty-acid ethanolamides (FAEs). Along with this precursor role, NAPEs might also serve autonomous signaling functions. Here, we report that
Palese, Francesca   +3 more
core  

A Comprehensive Review on Capillary Electrophoresis–Mass Spectrometry in Advancing Biomolecular Research

open access: yesELECTROPHORESIS, EarlyView.
ABSTRACT This review provides an in‐depth exploration of capillary electrophoresis–mass spectrometry (CE–MS) in biomolecular research from 2020 to 2024. CE–MS emerges as a versatile and powerful tool due to its numerous advantages, facilitating the analysis of various biomolecules, including proteins, peptides, oligonucleotides, and other metabolites ...
Laura Pont   +2 more
wiley   +1 more source

Pregnancy lipidomic profiles and DNA methylation in newborns from the CHAMACOS cohort. [PDF]

open access: yes, 2019
Lipids play a role in many biological functions and the newly emerging field of lipidomics aims to characterize the varying classes of lipid molecules present in biological specimens.
Bradman, Asa   +5 more
core  

Shotgun lipidomics of cardiolipin molecular species in lipid extracts of biological samples [PDF]

open access: hybrid, 2006
Xianlin Han   +4 more
openalex   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

open access: yesEpilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza   +4 more
wiley   +1 more source

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