Results 181 to 190 of about 30,733 (194)
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Metabolomics, Lipidomics, and Immunometabolism
2021Metabolomics, lipidomics, and the study of cellular metabolism are gaining increasing interest particularly in the field of immunology, since the activation and effector functions of immune cells are profoundly controlled by changes in cellular metabolic asset.
Carbone F. +8 more
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Profiling the Mammalian Lipidome by Quantitative Shotgun Lipidomics
2023The emerging field of lipidomics presents the systems biology approach to identify and quantify the full lipid repertoire of cells, tissues, and organisms. The importance of the lipidome is demonstrated by a number of biological studies on dysregulation of lipid metabolism in human diseases such as cancer, diabetes, and neurodegenerative diseases ...
Mads Møller, Foged +2 more
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2013
Lipids are a diverse group of compounds with multiple key biological functions. Lipidomics is a subdiscipline of metabolomics, with the focus on the global study of molecular lipids, including pathways and networks of cellular lipids in biological systems.
Pondia Pons, Isabel +1 more
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Lipids are a diverse group of compounds with multiple key biological functions. Lipidomics is a subdiscipline of metabolomics, with the focus on the global study of molecular lipids, including pathways and networks of cellular lipids in biological systems.
Pondia Pons, Isabel +1 more
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Current Opinion in Clinical Nutrition and Metabolic Care, 2012
Lipidomics characterizes the composition of intact lipid molecular species in biological systems and the field has been driven by some spectacular advances in mass spectrometry instrumentation and applications. This review will highlight these advances and outline their recent application to address clinical issues.This review first identifies recent ...
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Lipidomics characterizes the composition of intact lipid molecular species in biological systems and the field has been driven by some spectacular advances in mass spectrometry instrumentation and applications. This review will highlight these advances and outline their recent application to address clinical issues.This review first identifies recent ...
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Prostaglandins & Other Lipid Mediators, 2005
Lipidomics the systematic decoding of lipid-based information in biosystems is comprised of identification and profiling of lipids and lipid-derived mediators. As practiced today, lipidomics can be subdivided into architecture/membrane-lipidomics and mediator-lipidomics. The mapping of structural components and their relation to cell activation as well
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Lipidomics the systematic decoding of lipid-based information in biosystems is comprised of identification and profiling of lipids and lipid-derived mediators. As practiced today, lipidomics can be subdivided into architecture/membrane-lipidomics and mediator-lipidomics. The mapping of structural components and their relation to cell activation as well
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2007
Lipids are recognized as key participants in the regulation and control of cellular function, having important roles in signal transduction processes. The diversity in lipid chemical structure presents a challenge for establishing practical methods to generate and manage high volumes of complex data that translate into a snapshot of cellular lipid ...
Shankar Subramaniam +8 more
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Lipids are recognized as key participants in the regulation and control of cellular function, having important roles in signal transduction processes. The diversity in lipid chemical structure presents a challenge for establishing practical methods to generate and manage high volumes of complex data that translate into a snapshot of cellular lipid ...
Shankar Subramaniam +8 more
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Lipidomics of Alzheimer’s Disease
Bioanalysis, 2014Alzheimer's disease (AD) is a progressive brain disease that leads to an irreversible loss of neurons and cognition. It is the most common cause of dementia and can be considered as a major public health problem. At the histological level, AD is characterized by senile plaques and neurofibrillary tangles.
David Touboul +2 more
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The emergence of yeast lipidomics
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2007The emerging field of lipidomics, driven by technological advances in lipid analysis, provides greatly enhanced opportunities to characterize, on a quantitative or semi-quantitative level, the entire spectrum of lipids, or lipidome, in specific cell types.
Susan A. Henry +5 more
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Principles and practice of lipidomics
Journal of Inherited Metabolic Disease, 2014AbstractThe technical advances in mass spectrometry, particularly the development of (ultra)‐high‐resolution/mass accuracy measurement capabilities in combination with refinement of soft ionization techniques, have increased the application and success of lipidomics to answer biological questions in relation to lipid metabolism.
Vaz, F.M. +3 more
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Shotgun lipidomics: multidimensional MS analysis of cellular lipidomes
Expert Review of Proteomics, 2005Shotgun lipidomics, comprised of intrasource separation, multidimensional mass spectrometry and computer-assisted array analysis, is an emerging powerful technique in lipidomics. Through effective intrasource separation of predetermined groups of lipid classes based on their intrinsic electrical propensities, analyses of lipids from crude extracts of ...
Xianlin Han, Richard W. Gross
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