Results 221 to 230 of about 47,866 (282)

Investigation of the mechanism of Buyang Huanwu decoction in improving learning and memory impairment in Alzheimer's disease mice based on lipidomics. [PDF]

J Nat Med
Jiang J, Duo K, Zhu S, Wang Y, Xue H, Piao C, Ren Y, Lei X, Zhang Y, Liu J, Yang L, Zhang N.   +11 more
europepmc   +1 more source

Gut Microbiota Colonization in Early Life Influences Susceptibility to Adulthood Hepatic Lipid Accumulation in High‐Fat‐Diet‐Fed Mice

Advanced Science, Volume 12, Issue 21, June 5, 2025.
This study indicates that perinatal antibiotic exposure elevates susceptibility to high‐fat‐diet‐induced hepatic lipid accumulation via disrupting early‐life gut microbiota colonization. The decreased Lactobacillus colonization inhibits primary‐to‐secondary bile acid conversion, lowering secondary bile acids, enhancing adulthood intestinal lipid ...
Yan‐Yan Zhu, Xin Dong, Hao Zhou, Ze‐Yan Li, Bo Wang, Ya‐Ping Song, Zhi‐Bing Liu, Xue Lu, Yi‐Hao Zhang, Yichao Huang, Hua Wang, De‐Xiang Xu   +11 more
wiley   +1 more source

Nutrient migration and lipidomics changes in the liquid inner core of alkali-pickled duck egg yolk. [PDF]

Poult Sci
Jia D, Xie Y, Hu Z, Zhu D, Ye H, Qiu M, Geng F.   +6 more
europepmc   +1 more source

TRIM25‐Mediated INSIG1 Ubiquitination Promotes MASH Progression Through Reprogramming Lipid Metabolism

Advanced Science, Volume 12, Issue 21, June 5, 2025.
TRIM25‐mediated ubiquitination of INSIG1 serves as a key driver of lipid metabolism dysregulation in MASH progression. It identifies a novel small‐molecule inhibitor, C27H26N2O4S, which effectively inhibits TRIM25 activity, reducing lipid accumulation and inflammation.
Hao Zhang, Xiangxu Kong, Wei Wang, Huaxin Zhou, Haoran Qu, Zhengyao Guan, Honglei Wu, Xiangyu Zhai, Bin Jin   +8 more
wiley   +1 more source

Plasma and Liver Lipidomics Response to an Intervention of Rimonabant in ApoE*3Leiden.CETP Transgenic Mice

, 2011
Chunxiu Hu, Heng Wei, Anita M. van den Hoek, Mei Wang, Rob van der Heijden, Gerwin Spijksma, Theo Reijmers, Jildau Bouwman, Suzan Wopereis, Louis M. Havekes, Elwin Verheij, Thomas Hankemeier, Guowang Xu, J. van der Greef   +13 more
openalex   +2 more sources

Metabolomics and Lipidomics Reveal the Metabolic Disorders Induced by Single and Combined Exposure of Fusarium Mycotoxins in IEC-6 Cells. [PDF]

Foods
Wang X, Xu Y, Yu H, Lu Y, Qian Y, Wang M.   +5 more
europepmc   +1 more source

Glycolysis‐Derived Lactate Induces ACSL4 Expression and Lactylation to Activate Ferroptosis during Intervertebral Disc Degeneration

Advanced Science, Volume 12, Issue 21, June 5, 2025.
Glycolysis‐derived lactate activates nucleus pulposus cell ferroptosis via Histon H3K18la‐mediated ACSL4 transcription and ACSL4 lactylation and aggravate intervertebral disc degeneration. Inhibiting glycolysis via gene silencing or chemical intervention reduces the production of lactate and ameliorates ferroptosis activation and nucleus pulposus ...
Kaiqiang Sun, Yangyang Shi, Chen Yan, Shunmin Wang, Linhui Han, Fudong Li, Ximing Xu, Yuan Wang, Jingchuan Sun, Zijian Kang, Jiangang Shi   +10 more
wiley   +1 more source

Lipidomics of Huntington's Disease: A Comprehensive Review of Current Status and Future Directions. [PDF]

Metabolites
Yilmaz A, Akyol S, Ashrafi N, Saiyed N, Turkoglu O, Graham SF.   +5 more
europepmc   +1 more source

Advancements in Ambient Ionisation Mass Spectrometry in 2024: An Annual Review

Analytical Science Advances, Volume 6, Issue 1, June 2025.
ABSTRACT The introduction of ambient ionisation mass spectrometry (AIMS) is among the most important developments in analytical chemistry in recent years. Enabling the direct analysis of samples in their native state with neither sample preparation nor chromatographic separation provides chemical characterisation in a matter of seconds.
Alisha Henderson, Liam M. Heaney, Stephanie Rankin‐Turner   +2 more
wiley   +1 more source

Effects of hot air drying on muscle quality, volatile flavor compounds, and lipid profiles in sword prawn (<i>Parapenaeopsis hardwickii</i>) based on physicochemical, GC-IMS, and UHPLC-MS/MS-based lipidomics analysis. [PDF]

Food Chem X
Zheng W, Yang R, Shui S, Zhan F, Wang L, Lu R, Benjakul S, Zhang B.   +7 more
europepmc   +1 more source