Results 51 to 60 of about 30,733 (194)
The Hitchhiker’s Guide to Untargeted Lipidomics Analysis: Practical Guidelines
Metabolites, 2021 Lipidomics is a newly emerged discipline involving the identification and quantification of thousands of lipids. As a part of the omics field, lipidomics has shown rapid growth both in the number of studies and in the size of lipidome datasets, thus ...
Dmitrii Smirnov +4 more
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Signal Transduction and Targeted Therapy, 2021 Lipidomics profiling workflow. (a) Plasma lipidomics extraction was accomplished by fractionating samples into pools of species with similar physicochemical properties using appropriate combinations of organic solvents, after the addition of an internal ...
Jia-Xi Chen +8 more
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Diet, Cancer, and the Lipidome [PDF]
Cancer Epidemiology, Biomarkers & Prevention, 2006 Abstract The potential for dietary fat to interfere with the development of breast cancer by delaying its occurrence makes the identification of defined molecules a mandatory step in cancer prevention. In order to circumvent the limitations and/or bias of dietary exposure assessment tools, biomarkers of past lipid intake such as the ...
Bougnoux, Philippe +2 more
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Environmental HealthBackground Perfluoroalkyl and polyfluoroalkyl substances (PFAS) exposure has been associated with metabolic diseases, however, the underlying molecular pathogenesis remains to be understood.
Kothandaraman Narasimhan +7 more
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Analysis and Quantification of the Mitochondrial–ER Lipidome
Bio-ProtocolMitochondria are vital organelles essential for cellular functions, but their lipid composition and response to stressors are not fully understood.
Alexis Diaz-Vegas +2 more
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Recommendations for good practice in MS-based lipidomics
Journal of Lipid Research, 2021 In the last 2 decades, lipidomics has become one of the fastest expanding scientific disciplines in biomedical research. With an increasing number of new research groups to the field, it is even more important to design guidelines for assuring high ...
Harald C. Köfeler +8 more
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Lipidomic analyses in epidemiology [PDF]
International Journal of Epidemiology, 2016 Clinical lipid measurements have been the mainstay of risk assessment for chronic disease since the Framingham study commenced over 60 years ago. Thousands of subsequent epidemiological studies have provided much insight into the relationship between plasma lipid profiles, health and disease.
Jonathan E. Shaw +3 more
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Flexibility of a Eukaryotic Lipidome – Insights from Yeast Lipidomics
PLoS ONE, 2012 Mass spectrometry-based shotgun lipidomics has enabled the quantitative and comprehensive assessment of cellular lipid compositions. The yeast Saccharomyces cerevisiae has proven to be a particularly valuable experimental system for studying lipid-related cellular processes.
Felix Meyenhofer +5 more
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Journal of Lipid Research, 2013 We showed earlier that nutritional stress like starvation or high-fat diet resulted in phenotypic changes in the lipidomes of hepatocyte lipid droplets (LDs), representative for the pathophysiological status of the mouse model.
Chandramohan Chitraju +9 more
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The challenge of brain lipidomics [PDF]
Prostaglandins & Other Lipid Mediators, 2005 After many years backstage, lipids have made a come back in the limelight of neuroscience. This renewed excitement was sparked by a series of convergent discoveries in the fields of neural development, synaptic physiology and receptor pharmacology, which have begun to reveal the roles played by lipid messengers and their receptors in brain function ...
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