Insights into the CD1 lipidome
CD1 isoforms are MHC class I-like molecules that present lipid-antigens to T cells and have been associated with a variety of immune responses. The lipid repertoire bound and presented by the four CD1 isoforms may be influenced by factors such as the cellular lipidome, subcellular microenvironment, and the properties of the binding pocket.
Rita Szoke-Kovacs+4 more
openaire +3 more sources
Characterization and direct quantitation of sphingoid base-1-phosphates from lipid extracts: a shotgun lipidomics approach [PDF]
Xuntian Jiang, Xianlin Han
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Accurate detection and quantification of mRNA isoforms from nanopore long-read sequencing remains challenged by technical noise, particularly in single cells. To address this, we introduce Isosceles, a computational toolkit that outperforms other methods
Michal Kabza+6 more
doaj +1 more source
Alterations in lipid homeostasis of mouse dorsal root ganglia induced by apolipoprotein E deficiency: a shotgun lipidomics study [PDF]
Hua Cheng, Xuntian Jiang, Xianlin Han
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Alkaline methanolysis of lipid extracts extends shotgun lipidomics analyses to the low-abundance regime of cellular sphingolipids [PDF]
Xuntian Jiang+4 more
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To evaluate the modulation of RNA-related epigenetic factors by dietary interventions in hyperlipidemia (HL), male Golden-Syrian hamsters fed 16-weeks a high-fat diet (HFD, standard chow plus 3% cholesterol/15% butter) were subjected for another 5 weeks ...
Loredan S. Niculescu+5 more
doaj
Lipidomic analysis of the retina in a rat model of Smith–Lemli–Opitz syndrome: alterations in docosahexaenoic acid content of phospholipid molecular species [PDF]
David A. Ford+5 more
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A Laboratory Information Management System for High-Throughput Experimental Lipidomics: Minimal Information Required for the Analysis of Lipidomics Experiments (MIALE) [PDF]
Robert W. Byrnes+2 more
openalex +1 more source