Results 81 to 90 of about 47,866 (282)
Annals of Neurology, EarlyView.This final part 3 review builds on the practical applications discussed in part 2 and explores how artificial intelligence (AI) is transforming data management, neurological education, and neurological care across large healthcare networks and datasets. The review also highlights AI's role in real‐world and synthetic data, digital twins, and innovative
Matthew Rizzo
wiley +1 more source
Rhapso : automatic stitching of mass segments from fourier transform ion cyclotron resonance mass spectra [PDF]
, 2019 Fourier transform ion cyclotron resonance mass spectrometry (FTICR MS) provides the resolution and mass accuracy needed to analyze complex mixtures such as crude oil.
Barrow, Mark P. +5 more
core +2 more sources
Lipidomics: Developments and applications [PDF]
Journal of Chromatography B, 2009 Lipidomics, defined as the large-scale study of cellular lipids (i.e., the lipidome), has recently emerged as a rapidly expanding research field under the umbrella of systems biology [1–4]. Investigators in lipidomics examine the structures, functions, interactions, and dynamics of cellular lipids, identify their cellular localization (i.e. subcellular
openaire +3 more sources
The challenge of brain lipidomics [PDF]
Prostaglandins & Other Lipid Mediators, 2005 After many years backstage, lipids have made a come back in the limelight of neuroscience. This renewed excitement was sparked by a series of convergent discoveries in the fields of neural development, synaptic physiology and receptor pharmacology, which have begun to reveal the roles played by lipid messengers and their receptors in brain function ...
openaire +5 more sources
Angewandte Chemie International Edition, Accepted Article.Visualizing cholesterol dynamics in living systems in situ remains a fundamental challenge in biomedical imaging. While fluorescence microscopy requires bulky tags that perturb small molecule behavior, stimulated Raman scattering (SRS) microscopy enables label‐free detection of CH‐rich molecules.
Yongqing Zhang +7 more
wiley +1 more source
In-Vivo Lipidomics using Single-Cell Raman Spectroscopy [PDF]
, 2010 We describe a method for direct, quantitative, in vivo lipid profiling of oil producing microalgae using single-cell laser-trapping Raman spectroscopy (LTRS).
Ann Oliver +5 more
core +1 more source
Classifying Hypoxia in Breast Cancer Xenografts Using a Single‐Cell Mass Spectrometry Imaging Model
Analysis &Sensing, EarlyView.Hypoxia is a common feature in solid tumors and is linked to aggressiveness and therapy resistance. This study uses single‐cell mass spectrometry imaging of cultured cells exposed to different oxygen levels to spatially classify hypoxia in breast cancer xenografts.
Britt S. R. Claes +7 more
wiley +1 more source
Biomarkers and subtypes of deranged lipid metabolism in non-alcoholic fatty liver disease. [PDF]
, 2019 Nonalcoholic fatty liver disease (NAFLD) is a heterogeneous and complex disease that is imprecisely diagnosed by liver biopsy. NAFLD covers a spectrum that ranges from simple steatosis, nonalcoholic steatohepatitis (NASH) with varying degrees of fibrosis,
Alonso, Cristina +3 more
core
Animal Research and One Health, EarlyView.Mechanisms of light in regulating the chick pineal clock. Abstract The circadian clock significantly impacts animal health and productivity, with light playing a crucial role in regulating circadian rhythms. However, the mechanisms behind light‐induced circadian transmission remain unclear, particularly in light‐sensitive avian species.
Yunlei Li +10 more
wiley +1 more source
Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis
BMEMat, EarlyView.This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang +6 more
wiley +1 more source