Results 101 to 110 of about 35,244 (209)

Neutrophil Gelatinase-associated Lipocalin Significantly Correlates with Ischemic Damage in Patients Undergoing Laparoscopic Partial Nephrectomy

Balkan Medical Journal, 2019
Background:Laparoscopic partial nephrectomy, which minimizes renal function loss due to its nephron sparing nature, has become a standard technique among many experienced centers worldwide for surgical treatment of localized kidney tumors.
Meltem Savran Karadeniz, Isbara Alp Enişte, Hayriye Şentürk Çiftçi, Sebahat Usta, Tzevat Tefik, Öner Şanlı, Kamil Pembeci, Kamil Mehmet Tuğrul   +7 more
doaj   +1 more source

The interplay between pulsatility, sympathetic regulation and renal physiology: Implications for left ventricular assist devices

Experimental Physiology, EarlyView.
Abstract Left ventricular assist devices have gained traction both as a bridge therapy and as a destination therapy in the management of heart failure. Many of these devices reinstate blood flow in a continuous manner as opposed to the pulsatile flow present in normal physiology.
Tania Warnakulasuriya, Zaid Bahi, Rohit Ramchandra   +2 more
wiley   +1 more source

Edible Insect Allergens: An Emerging Food Safety Challenge

Sustainable Food Proteins, Volume 4, Issue 3, September 2026.
Allergic responses to edible insects arise via two main pathways: cross‐reactivity with homologous arthropod allergens and primary sensitization to edible insect proteins, both leading to IgE‐mediated immune activation. ABSTRACT Edible insects are increasingly promoted as sustainable protein sources; however, their allergenic potential remains a ...
Changqi Liu, Cassandra Maya, John J. Love, Huilian Che, Ke Chen, Jing Zhao   +5 more
wiley   +1 more source

Oral Spermidine Supplementation Preserves Submandibular Gland Function After Radiotherapy: Mechanistic Insights and Use in a Phase II Randomized Clinical Trial

MedComm, Volume 7, Issue 8, August 2026.
Radiotherapy‐induced xerostomia severely impairs quality of life. Integrated multiomics, organoids, murine models, and a randomized Phase II trial identified spermidine as a key radiation‐responsive metabolite. Oral spermidine preserved salivary gland function, maintained acinar cell integrity through Golgi‐mediated posttranslational modifications ...
Yu Min, Kun Gao, Yingtong Liu, Lei Dai, Xingchen Peng   +4 more
wiley   +1 more source

Machine Learning Predicts Treatment Response and Prognostic Pathways From Whole‐Blood Transcriptome in Primary Biliary Cholangitis

Liver International, Volume 46, Issue 8, August 2026.
ABSTRACT Background and Aims Prognostic biomarkers that link disease progression and/or responses to therapeutic interventions in patients with primary biliary cholangitis (PBC) remain undefined. In this study, we used a machine learning (ML) approach with whole‐blood transcriptomic data to predict clinical outcomes in response to obeticholic acid (OCA)
Hussain Syed, Ning Sun, Doaa Waly, Varinder Verma, Matthew Smith, David Shapiro, Mary Erickson, Kathy Siminovitch, Mark Swain, Mohammed S. Osman, Andrew L. Mason   +10 more
wiley   +1 more source

Clinical and molecular correlates of digitally quantified anthracosis in lung tissue slides: utility of an automated quantitative workflow

The Journal of Pathology: Clinical Research, Volume 12, Issue 4, July 2026.
Abstract Air pollution, such as particulate matter with a diameter of ≤2.5 μm (PM2.5) is a major contributor to lung cancer in the never‐smoking population. Anthracotic pigments (black deposits in the lungs) are physical evidence of environmental exposures. While links between anthracosis and lung disease have been established, anthracosis has not been
Lucas C Fung, Brenden Joseph, Kenneth Ofori‐Amanfo, Theodora Lo, Peiyao Wang, Mark Trinder, Georgina Barnabas, Taysia Nikaido‐Landry, Clinton H Durney, Aadetri Tawara, Sharon Ong, Stephen Lam, Rafael Meza, Renelle Myers, William W Lockwood, Anna McGuire, Julia R Naso, Emilia L Lim   +17 more
wiley   +1 more source

Treatment of Restless Legs Syndrome in Dialysis Patients

Seminars in Dialysis, EarlyView.
Kenji Sakurai, Yoshitaka Kurihara, Hiromi Hosoya, Fumi Yamouchi, Takeshi Saito   +4 more
wiley   +1 more source

A Review and Future Perspective on Renal Outcome Definitions in Lupus Nephritis

ACR Open Rheumatology, Volume 8, Issue 7, July 2026.
Lupus nephritis (LN) remains a leading cause of morbidity and mortality in systemic lupus erythematosus, yet the lack of standardized definitions for renal outcomes hinders effective diagnosis, prognosis, treatment personalization, comparisons across trials, and interpretable trial endpoints.
Ioannis Parodis, Tina Kochar, Frank Cortazar, Yoshiya Tanaka, Nehad Soloman   +4 more
wiley   +1 more source

Icariin Alleviates Diabetes‐Associated Cognitive Dysfunction Through Modulation of LCN2–MEK/ERK Signaling‐Associated Neuroinflammation

CNS Neuroscience &Therapeutics, Volume 32, Issue 7, July 2026.
Icariin protects against diabetes‐associated cognitive dysfunction by effectively inhibiting the LCN2–MEK/ERK axis and alleviating neuroinflammation. These findings demonstrate that targeting this signaling pathway with icariin may offer a promising strategy for treating cognitive impairment in diabetes. ABSTRACT Objective Diabetes‐associated cognitive
Xinyi Jiao, Yutong Ren, Ziman Yu, Junxiong Zhou, Danyang Wang, Bin Yan, Guoqing Tian   +6 more
wiley   +1 more source

Feeding Strategy Shapes the Evolution of the Hyaluronidase Gene Family in Medicinal Leeches

Ecology and Evolution, Volume 16, Issue 7, July 2026.
We investigated the molecular evolution and expression divergence of the hyaluronidase gene family across eight medicinal leech species with contrasting feeding strategies. Hematophagous species retained a complete five‐member gene repertoire and exhibited elevated dN/dS values and significantly elevated gene expression compared to non‐hematophagous ...
Rujiao Sun, Xingke Fu, Rui Ai, Zuhao Huang, Huanhuan Li, Lizhou Tang, Huanhuan Chen, Xiongsheng Zhang, Fang Zhao, Gonghua Lin   +9 more
wiley   +1 more source