Results 111 to 120 of about 24,464,671 (254)

The miR‐145‐5p/NRF2/SLC7A11 axis regulates ferroptosis‐mediated renal tubular epithelial cell injury in diabetic nephropathy

open access: yesJournal of Diabetes Investigation, EarlyView.
Suppression of miR‐145‐5p alleviates DN‐associated renal tissue damage by inhibiting NRF2/SLC7A11‐mediated ferroptosis of RTECs. ABSTRACT Purpose This study aimed to investigate the molecular mechanism by which the miR‐145‐5p/NRF2/SLC7A11 axis regulates ferroptosis‐mediated renal tubular epithelial cell (RTEC) injury in diabetic nephropathy (DN ...
Ganlin Wu   +5 more
wiley   +1 more source

USE OF LIPOCALIN-2 AS A DIAGNOSTIC MARKER AND THERAPEUTIC TARGET [PDF]

open access: yes, 2008
Methods and compositions for identifying and treating obesity and obesity-induced metabolic disorders are provided. One aspect provides a method for the evaluation of risk and progression of glucose tolerance, insulin resistance and Type 2 diabetes in ...

core   +2 more sources

USE OF LIPOCALIN-2 AS A DIAGNOSTIC MARKER AND THERAPEUTIC TARGET [PDF]

open access: yes, 2010
Methods and compositions for identifying and treating obesity and obesity-induced metabolic disorders are provided. One aspect provides a method for the evaluation of risk and progression of glucose tolerance, insulin resistance and Type 2 diabetes in ...

core   +2 more sources

Down-Regulation of Lipocalin 2 Expression in Mouse Testis after Exposure to Electromagnetic Field [PDF]

open access: yesIranian Journal of Medical Sciences, 2009
Background: The effects of electromagnetic field (EMF) onreproductive system have been of critical concern for a longtime. It has been shown that the EMF can adversely affect testicularcells and tissue and decrease male fertility.
Amaneh Mohammadi Roushandeh   +6 more
doaj  

Lipocalin 2 Upregulation Protects Hepatocytes from IL1-β-Induced Stress

open access: yesCellular Physiology and Biochemistry, 2015
Background: Lipocalin 2 (LCN2), a protein primarily produced by hepatocytes, is highly upregulated under various conditions that induce cellular stress, such as intoxication, infection or inflammation.
Ying Hu   +13 more
doaj   +1 more source

Long‐term effects of tofogliflozin on renal function in patients with type 2 diabetes: A retrospective multicenter study

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Aims To investigate the long‐term renal effects of tofogliflozin, with the shortest half‐life among sodium–glucose cotransporter 2 inhibitors, in real‐world clinical practice. Materials and methods We retrospectively enrolled patients with type 2 diabetes mellitus treated at three affiliated hospitals between January 2015 and May 2024.
Natsuko Shinagawa   +13 more
wiley   +1 more source

The Effect of Three-Week Intensive Interval Training on Lipocalin-2 and Interleukin1-β in Healthy and Adult Rat Hippocampus [PDF]

open access: yesMajallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2017
Background: In response to the exercise, variety of inflammatory and anti-inflammatory changes in cytokines were occurred into the tissue spaces and also to the systemic circulation.
Bahman Hasanvand   +3 more
doaj  

Catheter‐Associated Urinary Tract Infections in Children: An Evidence‐Informed Narrative Review of Diagnosis, Management and Prevention

open access: yesJournal of Paediatrics and Child Health, EarlyView.
ABSTRACT Catheter‐associated urinary tract infections (CAUTI) are a common healthcare‐associated infection in children and a major contributor to increased morbidity, prolonged hospital stays and higher healthcare costs. This narrative review uses an evidence‐informed approach highlighting recent paediatric literature (2000–2025) to provide an overview
Simon P. Paget   +4 more
wiley   +1 more source

Lipocalin-2 mediates linoleic acid-induced endothelial dysfunction

open access: yes, 2012
Lipocalin-2, a 25kDa glycoprotein secreted by adipocytes, mediates endothelial dysfunction induced by dietary obesity in mice. The mechanisms underlying the deteriorating effect of lipocalin-2 on endothelial function are not fully understood. The present
Song, E   +4 more
core  

Neutrophil Gelatinase-Associated Lipocalin induces the expression of heme oxygenase-1 and superoxide dismutase 1, 2 [PDF]

open access: yes, 2010
Lipocalin-2 (Lcn2, NGAL) is a member of the lipocalin super family with diverse function such as the induction of apoptosis, the suppression of bacterial growth, and modulation of inflammatory response.
Halabian, R.   +8 more
core  

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