Results 121 to 130 of about 24,464,671 (254)

Clinical Prediction Models for Acute Kidney Injury in Neonatology—A Systematic Review and Modelling Analysis

open access: yesJournal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aims Acute kidney injury (AKI) affects up to one‐third of neonates admitted to neonatal intensive care units (NICUs). NICUs are highly data‐rich environments, offering opportunities to develop clinical prediction rules (CPRs) that use clinical and demographic data to estimate AKI risk.
Dermot Wildes   +7 more
wiley   +1 more source

Saliva Liquid Biopsy for Detection of Oral and Systemic Diseases

open access: yesJournal of Periodontal Research, EarlyView.
This Review summarizes and discusses the biological foundations and major classes of salivary biomarkers, outlines collection methods and analytical protocols for saliva‐based liquid biopsy, and technological convergences driven by multi‐omics approaches, artificial intelligence, and point‐of‐care devices in the application of oral and systemic ...
Irene Choi   +10 more
wiley   +1 more source

Exploring some pro-inflammatory cytokines and adipokines as novel biomarkers in polycystic ovary syndrome

open access: yesItalian Journal of Medicine
Non-communicable diseases are more likely to affect women with polycystic ovarian syndrome (PCOS), in particular, mostly ascribed to the existence of low-grade chronic inflammation brought on by adipokines and proinflammatory cytokines.
Dlvin Akif Mustafa   +1 more
doaj   +1 more source

Design Principles of Plant Thermotolerance: Integrating Photosynthesis, Reproduction, and Field Resilience in a Warming Climate

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Global food security is increasingly threatened by climate change, as rising temperatures compromise the yields of major staple crops, including wheat, rice, and maize. Enhancing plant thermotolerance has therefore become a critical priority for sustaining agricultural productivity.
Yuchen Qu, Wataru Yamori
wiley   +1 more source

Seven days of mixed‐method heat acclimation improved markers of cardiovascular and fluid‐regulatory strain during exercise‐heat stress

open access: yesExperimental Physiology, EarlyView.
Abstract A mixed‐method heat acclimation (HA) protocol may optimise performance by supporting the training taper while promoting thermal adaptation; however, the impact on cardiovascular and fluid‐regulatory adjustments to protect health is unknown. Therefore, we examined the effects of a mixed‐method heat protocol on physiological responses, including
Daniel Snape   +5 more
wiley   +1 more source

One day of environment‐induced heat stress causes injury to the murine kidney

open access: yesExperimental Physiology, EarlyView.
Abstract Environment‐induced heat stress (EIHS) results from sustained body temperature elevation owing to prolonged exposure to heat and humidity. We hypothesized that EIHS would cause kidney injury and cellular dysfunction. To test this hypothesis, female C57 mice were exposed to EIHS (n = 14; 37.6°C, 42.0% relative humidity) or thermoneutral (TN ...
Melissa Roths   +3 more
wiley   +1 more source

Increased serum levels of lipocalin-1 and -2 in patients with stable chronic obstructive pulmonary disease

open access: yes, 2014
Xiao-ru Wang,1,* Yong-pu Li,2,* Shui Gao,2 Wei Xia,2 Kun Gao,1 Qing-hua Kong,1 Hui Qi,1 Ling Wu,1 Jing Zhang,3 Jie-ming Qu,4 Chun-xue Bai3 1Department of Pulmonary Medicine, Dahua Hospital, Xuhui District, Shanghai, 2Department of Pulmonary Medicine ...
Kong QH   +10 more
core  

Role of lipocalin-2 in cardiac dysfunction associated with aging and dietary obesity

open access: yes, 2012
Obesity is closely related to many medical complications such as type 2 diabetes, hypertension and heart failure. Obesity and other factors, including elevated blood glucose levels, hypertension, and dyslipidemia, constitute a constellation of ...
杨波, Yang, Bo
core   +1 more source

Effect of foot immersion and neck cooling on renal, intestinal, immune and inflammatory markers in older adults exposed to extreme heat

open access: yesExperimental Physiology, EarlyView.
Abstract Older adults with reduced thermoregulatory capabilities are increasingly at risk of heat‐related pathophysiological outcomes (e.g., acute kidney injury, heatstroke) due to increasingly frequent, prolonged and intense heatwaves. Foot immersion and neck cooling have been proposed as practical, non‐electrical cooling strategies for protecting ...
Thomas McCarthy   +7 more
wiley   +1 more source

Tripterine Liposome Exerts Antitumor and Immunomodulatory Effects in Pancreatic Ductal Adenocarcinoma

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Tripterine liposome (TP‐lipo) exerts anti‐pancreatic ductal adenocarcinoma (PDAC) effects through direct suppression of tumor cells and modulation of the tumor microenvironment (TME). TP‐lipo induces apoptosis and inhibits the clonogenicity, migration, and invasion of KPC cells in vitro.
Lirui Tang   +8 more
wiley   +1 more source

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