Results 101 to 110 of about 11,446 (217)

Nilai Diagnostik Neutrophil Gelatinase-Associated Lipocalin Urin, Kelainan Urinalisis, dan Kombinasi Keduanya pada Infeksi Saluran Kemih Anak Usia 2–5 Tahun

Sari Pediatri
Latar belakang. Infeksi saluran kemih (ISK) pada anak memiliki manifestasi klinis yang tidak khas sehingga sulit untuk diagnosis dini. Biakan urin memerlukan waktu hingga lima hari sehingga dapat menyebabkan keterlambatan terapi serta tingginya ...
Citra Estetika, Sudung O. Pardede, Zakiudin Munasir, Bambang Supriyatno, Titis Prawitasari, Piprim Basarah Yanuarso   +5 more
doaj   +1 more source

Macrophage Lipid Homeostasis Drives IVDD via a Senescence‐Dependent Impairment of Efferocytosis

Cell Proliferation, EarlyView.
Intervertebral disc degeneration (IVDD) has been a leading cause of low back pain and lacks disease‐modifying therapies. Although dysregulated disc lipid metabolism is implicated, its impact on the immune microenvironment, particularly macrophages, remains unknown.
Jinyu Wang, Shiyong Ling, Qi Wang, Xuege Qiao, Jianpeng Xing, Siyang Ji, Linhui Han, Chen Yan, Zhishen Niu, Lei Yuan, Baolian Zhao, Kaiqiang Sun, Jiangang Shi   +12 more
wiley   +1 more source

Lipocalin-2 as an Infection-Related Biomarker to Predict Clinical Outcome in Ischemic Stroke. [PDF]

, 2016
OBJECTIVES:From previous data in animal models of cerebral ischemia, lipocalin-2 (LCN2), a protein related to neutrophil function and cellular iron homeostasis, is supposed to have a value as a biomarker in ischemic stroke patients.
Paul Kendlbacher (2735104), Seifert-Held, Thomas, Manuel Zeitelhofer, Thomas Pekar (435519), Manuel Zeitelhofer (150938), Pekar, T, Haindl, Michaela, Kendlbacher, Paul, Fazekas, F, Michaela Haindl (511056), Pekar, Thomas, Zeitelhofer, M,, Andreas Meisel, Adzemovic, MZ, Paul Kendlbacher, Zeitelhofer, Manuel, Odilo Engel, Sonja Hochmeister, Michaela Haindl, Andreas Meisel (46731), Hochmeister, S, Adzemovic, Milena Z., Fazekas, Franz, Thomas Seifert-Held, Franz Fazekas, Thomas Seifert-Held (435518), Engel, O, Kendlbacher, P, Haindl, M, Thomas Pekar, Meisel, Andreas, Milena Z. Adzemovic (150933), Hochmeister, Sonja, Sonja Hochmeister (150941), Franz Fazekas (160774), Engel, Odilo, Meisel, A, Milena Z Adzemovic, Odilo Engel (768886), Seifert-Held, T   +39 more
core   +2 more sources

From biology to biotechnology: Host‐regulation factors from parasitoid wasps are a source of bioactive molecules with translational potential

Insect Molecular Biology, EarlyView.
Parasitoid wasps deploy maternal and embryonic factors to reprogramme host physiology. Venom, calyx fluid, polydnaviruses, teratocytes and larval secretions act in a coordinated, compartmentalised manner. Host‐regulation factors are promising sources of insecticidal, antimicrobial and bioinspired translational molecules.
Ciro Pedro G. Pinto, Andrew A. Walker, Glenn F. King   +2 more
wiley   +1 more source

Urinary Neutrophil Gelatinase-Associated Lipocalin to Monitor Lupus Nephritis Disease Activity

, 2015
Background This study was conducted to determine whether there is an association between urinary neutrophil gelatinase-associated lipocalin (uNGAL) and urinary transforming growth factor-β1 (uTGF-β1) with lupus nephritis (LN) disease activity.
Handono Kalim, Jullyanny W. Wijaya, Ati Rastini, Atma Gunawan, Hani Susianti, Kusworini Handono   +5 more
core   +1 more source

Tear Lipocalin: structure and Function [PDF]

The Ocular Surface, 2011
Lipocalins are a family of diverse low molecular weight proteins that act extracellularly. They use multiple recognition properties that include 1) ligand binding to small hydrophobic molecules, 2) macromolecular complexation with other soluble macromolecules, and 3) binding to specific cell surface receptors to deliver cargo. Tear lipocalin (TLC) is a
openaire   +2 more sources

The miR‐145‐5p/NRF2/SLC7A11 axis regulates ferroptosis‐mediated renal tubular epithelial cell injury in diabetic nephropathy

Journal of Diabetes Investigation, EarlyView.
Suppression of miR‐145‐5p alleviates DN‐associated renal tissue damage by inhibiting NRF2/SLC7A11‐mediated ferroptosis of RTECs. ABSTRACT Purpose This study aimed to investigate the molecular mechanism by which the miR‐145‐5p/NRF2/SLC7A11 axis regulates ferroptosis‐mediated renal tubular epithelial cell (RTEC) injury in diabetic nephropathy (DN ...
Ganlin Wu, Yu Fang, Meirong Xu, Zuopeng Lu, Yu Cao, Yana Gao   +5 more
wiley   +1 more source

Lipocalin-2 and its variants

, 2020
Lipocalin-2 is a proinflammation adipokine, which is characterized by highly diversified expression and structure-function relationship. Due to the dynamic ligand-binding, protein-protein interaction and posttranslational modification, lipocalin-2 exists
李大慧, Li, Dahui
core  

Long‐term effects of tofogliflozin on renal function in patients with type 2 diabetes: A retrospective multicenter study

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Aims To investigate the long‐term renal effects of tofogliflozin, with the shortest half‐life among sodium–glucose cotransporter 2 inhibitors, in real‐world clinical practice. Materials and methods We retrospectively enrolled patients with type 2 diabetes mellitus treated at three affiliated hospitals between January 2015 and May 2024.
Natsuko Shinagawa, Hiroshi Okada, Junya Hironaka, Shinta Yamamoto, Mari Yoneda, Sayaka Kawai, Yuto Saijyo, Tomoya Katayama, Hanako Nakajima, Akio Kishi, Noriyuki Kitagawa, Naoko Nakanishi, Masahide Hamaguchi, Michiaki Fukui   +13 more
wiley   +1 more source

Lipocalin-2 gene expression during liver regeneration after partial hepatectomy in rats

, 2014
Background: Lipocalin-2 (Lcn2) is related to cell proliferation. We studied Lcn2 gene expression during liver regeneration after partial hepatectomy (PH). Methods: Male Wistar rats were sacrificed before and 2, 4, 6, 12, 24, 72 h, 7 days after 70% or 40%
Lai, Hong-Shiee;Wu, Yao-Ming;Lai, Shuo-Lun;Lin, Wen-Hsi, 賴鴻緒   +1 more
core   +1 more source