Results 121 to 130 of about 11,446 (217)

Commentary: Allergen and Epitope Targets of Mouse-Specific T Cell Responses in Allergy and Asthma

Frontiers in Immunology, 2019
Tuomas Virtanen, Marja Rytkönen-Nissinen   +1 more
doaj   +1 more source

One day of environment‐induced heat stress causes injury to the murine kidney

Experimental Physiology, EarlyView.
Abstract Environment‐induced heat stress (EIHS) results from sustained body temperature elevation owing to prolonged exposure to heat and humidity. We hypothesized that EIHS would cause kidney injury and cellular dysfunction. To test this hypothesis, female C57 mice were exposed to EIHS (n = 14; 37.6°C, 42.0% relative humidity) or thermoneutral (TN ...
Melissa Roths, Alyona Michael, Zachary J. Schlader, Joshua T. Selsby   +3 more
wiley   +1 more source

Effect of foot immersion and neck cooling on renal, intestinal, immune and inflammatory markers in older adults exposed to extreme heat

Experimental Physiology, EarlyView.
Abstract Older adults with reduced thermoregulatory capabilities are increasingly at risk of heat‐related pathophysiological outcomes (e.g., acute kidney injury, heatstroke) due to increasingly frequent, prolonged and intense heatwaves. Foot immersion and neck cooling have been proposed as practical, non‐electrical cooling strategies for protecting ...
Thomas McCarthy, Ben J. Lee, James J. McCormick, Kelli E. King, Emma R. McCourt, Luana C. Main, Robert D. Meade, Glen P. Kenny   +7 more
wiley   +1 more source

Correlation of serum neutrophil gelatinase-associated lipocalin with acute kidney injury in hypertensive disorders of pregnancy

, 2013
ML Patel,1 Rekha Sachan,2 Radheyshyam Gangwar,3 Pushpalata Sachan,4 SM Natu51Department of Medicine, King George's Medical University, Lucknow, Uttar Pradesh, India; 2Department of Obstetrics and Gynaecology, King George's Medical University ...
Natu SM, Sachan P, Sachan R, Patel ML, Gangwar R   +4 more
core  

Lipocalin‐2 as a prognostic biomarker and its association with systemic inflammation in small cell lung cancer

Thoracic Cancer
Background Systemic inflammation is believed to contribute to small cell lung cancer (SCLC) progression, but the underlying relationship remains unclear.
Se‐Il Go, Jung Wook Yang, Woo Je Lee, Eun Jeong Jeong, Sungwoo Park, Gyeong‐Won Lee   +5 more
doaj   +1 more source

Tripterine Liposome Exerts Antitumor and Immunomodulatory Effects in Pancreatic Ductal Adenocarcinoma

MedComm, Volume 7, Issue 10, October 2026.
Tripterine liposome (TP‐lipo) exerts anti‐pancreatic ductal adenocarcinoma (PDAC) effects through direct suppression of tumor cells and modulation of the tumor microenvironment (TME). TP‐lipo induces apoptosis and inhibits the clonogenicity, migration, and invasion of KPC cells in vitro.
Lirui Tang, Yi Lin, Xueqin Jiang, Xiaohe Tian, Giuseppe Battaglia, Yuquan Wei, Wenshuang Wu, Xuemei He, Xiawei Wei   +8 more
wiley   +1 more source

The impact of lipocalin-type-prostaglandin-D-synthase as a predictor of kidney disease in patients with type 2 diabetes

, 2015
Marcelo Rodrigues Bacci1, Marina Romera Cavallari1, Ross Martin de Rozier-Alves2, Beatriz da Costa Aguiar Alves2, Fernando Luiz Affonso Fonseca2,31General Practice Department, 2Clinical Analysis Laboratory, ABC Medical School, 3Biological Sciences ...
Alves BCA, Bacci MR, de Rozier-Alves RM, Fonseca FLA, Cavallari MR   +4 more
core  

Mesenchymal Stem Cell‐Derived Extracellular Vesicles Ameliorate NaIO3‐Induced Dry AMD by Delivering miR‐486‐3p to Inhibit Lipocalin‐2‐Mediated Ferroptosis

MedComm, Volume 7, Issue 10, October 2026.
Our study reveals a novel mechanism by which MSC‐derived EVs alleviate NaIO3‐induced dry AMD‐like pathology. MSC‐EVs deliver miR‐486‐3p into retinal cells to directly inhibit the ferroptosis‐promoting target gene Lcn2. Concurrently, downregulated Lcn2 restores intracellular Gpx4 expression, thereby suppressing ferroptosis and rescuing retinal ...
Zheng Li, Tujing Zhao, Lin Ye, Runze Li, Huaping Tian, Ruilin Liao, Lulin Huang   +6 more
wiley   +1 more source

Human lipocalin-2 variants : therapeutic evaluations

Lipocalin-2 is a proinflammatory protein that undergoes post-translational modification by polyamination and has unique structure-function dynamics. The presence of different lipocalin-2 variants exhibits varied expression patterns. In the present study,
Li, Haoyun, 李皓雲
core  

Serum Neutrophil Gelatinase-Associated Lipocalin - A Sensitive Novel Marker of Renal Impairment in Liver Cirrhosis? [PDF]

, 2011
F. Bendtsen, Benesic, A, Møller, Søren, Moller, S., A. Benesic, Krag, A., Gerbes, Alexander L., Bendtsen, F, M. Vogeser, S. Møller, Vogeser, M., A.L. Gerbes, Vogeser, M, A. Krag, Benesic, A., Krag, Aleksander Ahm, Bendtsen, F., Gerbes, A L   +17 more
core   +1 more source