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Lipocalins as biochemical markers of disease
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 2000Lipocalins as biochemical markers of disease have been used extensively. The clinical indications relate to almost any field of medicine, such as inflammatory disease, cancer, lipid disorders, liver and kidney function. Some of the more well-known lipocalins that have been used as markers of disease are orosomucoid, Protein HC (alpha(1)-microglobulin),
S, Xu, P, Venge
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Iron, lipocalin, and kidney epithelia
American Journal of Physiology-Renal Physiology, 2003Brilliant new discoveries in the field of iron metabolism have revealed novel transmembrane iron transporters, novel hormones that regulate iron traffic, and iron's control of gene expression. An important role for iron in the embryonic kidney was first identified by Ekblom, who studied transferrin (Landschulz W and Ekblom P.
Jun, Yang +3 more
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Glycodelin: a reproduction-related lipocalin
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 2000Glycodelin, a human lipocalin, is a major endometrial protein with at least two differentially glycosylated isoforms. Glycodelin-A (GdA) is purified from human mid-trimester amniotic fluid, where it is secreted from the decidualized endometrium. Glycodelin-S (GdS) is synthesized in the male reproductive tract, mainly in the seminal vesicles, and ...
M, Halttunen +2 more
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The role of lipocalins in airway disease
Clinical & Experimental Allergy, 2013SummaryThe pathogenesis of allergic airway inflammation and disease is complex and still not fully understood. Many cells, factors and mediators are involved in the different aspects of induction, maintenance and persistence of airway inflammation. The heterogeneity and redundancy of this system is one of the main reasons why novel therapeutic targets ...
A M, Dittrich, H A, Meyer, E, Hamelmann
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Beyond the superfamily: the lipocalin receptors
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 2000Lipocalins are characterized by multiple molecular recognition properties including the ability to bind to cell surface receptors. Receptors for a number of lipocalins have been identified. These include receptors for alpha-1-microglobulin, insecticyanin, glycodelin, retinol-binding protein, alpha-1-acid glycoprotein, beta-lactoglobulin and odorant ...
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Lipocalins: unity in diversity
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 2000B, Akerstrom, D R, Flower, J P, Salier
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Lipocalin structure and function
Biochemical Society Transactions, 1993A, Sivaprasadarao +2 more
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The first prokaryotic lipocalins
Trends in Biochemical Sciences, 1995D R, Flower +3 more
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