Results 111 to 120 of about 35,010 (211)

Clinical and molecular correlates of digitally quantified anthracosis in lung tissue slides: utility of an automated quantitative workflow

The Journal of Pathology: Clinical Research, Volume 12, Issue 4, July 2026.
Abstract Air pollution, such as particulate matter with a diameter of ≤2.5 μm (PM2.5) is a major contributor to lung cancer in the never‐smoking population. Anthracotic pigments (black deposits in the lungs) are physical evidence of environmental exposures. While links between anthracosis and lung disease have been established, anthracosis has not been
Lucas C Fung, Brenden Joseph, Kenneth Ofori‐Amanfo, Theodora Lo, Peiyao Wang, Mark Trinder, Georgina Barnabas, Taysia Nikaido‐Landry, Clinton H Durney, Aadetri Tawara, Sharon Ong, Stephen Lam, Rafael Meza, Renelle Myers, William W Lockwood, Anna McGuire, Julia R Naso, Emilia L Lim   +17 more
wiley   +1 more source

Treatment of Restless Legs Syndrome in Dialysis Patients

Seminars in Dialysis, EarlyView.
Kenji Sakurai, Yoshitaka Kurihara, Hiromi Hosoya, Fumi Yamouchi, Takeshi Saito   +4 more
wiley   +1 more source

A Review and Future Perspective on Renal Outcome Definitions in Lupus Nephritis

ACR Open Rheumatology, Volume 8, Issue 7, July 2026.
Lupus nephritis (LN) remains a leading cause of morbidity and mortality in systemic lupus erythematosus, yet the lack of standardized definitions for renal outcomes hinders effective diagnosis, prognosis, treatment personalization, comparisons across trials, and interpretable trial endpoints.
Ioannis Parodis, Tina Kochar, Frank Cortazar, Yoshiya Tanaka, Nehad Soloman   +4 more
wiley   +1 more source

Role of Neutrophil Gelatinase–Associated Lipocalin in Early Acute Kidney Injury Detection and Hemodialysis Prediction

Turkish Journal of Nephrology
Background: Acute kidney injury (AKI) is a perilous condition often leading to high morbidity and mortality, particularly in critically ill patients.
Judhajit Maiti, Gerry George Mathew, Tushita Ghosh, Vellore Mohanakrishnan Viodhini, Ilango Suyampirakasam, Varadharajan Jayaprakash   +5 more
doaj   +1 more source

Icariin Alleviates Diabetes‐Associated Cognitive Dysfunction Through Modulation of LCN2–MEK/ERK Signaling‐Associated Neuroinflammation

CNS Neuroscience &Therapeutics, Volume 32, Issue 7, July 2026.
Icariin protects against diabetes‐associated cognitive dysfunction by effectively inhibiting the LCN2–MEK/ERK axis and alleviating neuroinflammation. These findings demonstrate that targeting this signaling pathway with icariin may offer a promising strategy for treating cognitive impairment in diabetes. ABSTRACT Objective Diabetes‐associated cognitive
Xinyi Jiao, Yutong Ren, Ziman Yu, Junxiong Zhou, Danyang Wang, Bin Yan, Guoqing Tian   +6 more
wiley   +1 more source

Feeding Strategy Shapes the Evolution of the Hyaluronidase Gene Family in Medicinal Leeches

Ecology and Evolution, Volume 16, Issue 7, July 2026.
We investigated the molecular evolution and expression divergence of the hyaluronidase gene family across eight medicinal leech species with contrasting feeding strategies. Hematophagous species retained a complete five‐member gene repertoire and exhibited elevated dN/dS values and significantly elevated gene expression compared to non‐hematophagous ...
Rujiao Sun, Xingke Fu, Rui Ai, Zuhao Huang, Huanhuan Li, Lizhou Tang, Huanhuan Chen, Xiongsheng Zhang, Fang Zhao, Gonghua Lin   +9 more
wiley   +1 more source

Salivary Extracellular Vesicles: Paradigm Shift in Liquid Biopsy Diagnostics

Journal of Extracellular Biology, Volume 5, Issue 7, July 2026.
ABSTRACT Extracellular vesicles (EVs), lipid bilayer nanoparticles released by virtually all cells, serve as essential messengers for intercellular communication. Due to their involvement in several pathophysiological processes, EVs have recently gained considerable attention as potentially diagnostic and prognostic biomarkers for various illnesses ...
Kwanele Xulu, Usri H. Ibrahim, Irene Mackraj, Carola Niesler   +3 more
wiley   +1 more source

The Role of Nitric Oxide, Lipocalin-2, and Proinflammatory Cytokines on Proteinuria and Insulin Resistance in Type 2 Diabetes Mellitus Subgroups

International Journal of General Medicine
Chung Hyun Nahm,1 Moon Hee Lee,2 Noriyoshi Fujii,3 Tatsuyoshi Fujii,4 Jong Weon Choi1 1Department of Laboratory Medicine, College of Medicine, Inha University, Incheon, Republic of Korea; 2Department of Internal Medicine, College of Medicine, Inha ...
Nahm CH, Lee MH, Fujii N, Fujii T, Choi JW   +4 more
doaj  

Ischemia–Reperfusion Injury: Molecular Mechanisms and Therapeutic Interventions

MedComm, Volume 7, Issue 7, July 2026.
Multiorgan ischemia–reperfusion injury begins with ischemia‐induced ATP depletion and ionic imbalance, followed by reperfusion‐triggered mitochondrial ROS/RNS bursts, regulated cell death, and DAMP release. Sterile inflammation converges on endothelial–immune–coagulation crosstalk, where NETs drive immunothrombosis, no‐reflow, and remote organ injury ...
Peng An, Yi An, Mengwei Chen, Longlong Wu, Rong Wang   +4 more
wiley   +1 more source

The Prognostic Role of Neutrophil Gelatinase-Associated Lipocalin and Kidney Injury Molecule-1 Expressions in Gastric Carcinomas

Current Oncology
Background: The survival rate among stomach adenocarcinoma patients is exceedingly low. NGAL (neutrophil gelatinase-associated lipocalin) has pivotal roles in cell proliferation, immunity, and tumorigenesis. KIM-1 (Kidney Injury Molecule-1), also referred to as TIM-1 and HAVcr-1, is a transmembrane glycoprotein located in healthy immune cells and ...
Duygu Ayaz, Gülden Diniz, Ayşe Gül Pulular, Dudu Solakoğlu Kahraman, Umut Varol, Nuket Özkavruk Eliyatkın, Sevil Sayhan, Ali Kemal Kayapınar   +7 more
openaire   +3 more sources