Results 51 to 60 of about 39,706 (298)

カベオリン異常症における特徴的な骨格筋MRI画像所見に関する検討 [PDF]

, 2019
博士(医学) 甲第702号(主論文の要旨、要約、審査結果の要旨、本文)，著者名:Kumiko IHIGURO・Takahiro NAKAYAMA・Masaru YOSHIOKA・Terumi MURAKAMI・Sachiko KAJINO・Minobu SHICHIJI・Takatoshi SATO・Naomi HINO-FUKUYO・Satoshi KURU・Makiko OSAWA・Satoru NAGATA・Mariko OKUBO・Nobuyuki MURAKAMI・Yukiko K ...
石黒 久美子
core   +2 more sources

Lipodystrophy in HIV/AIDS patients with different levels of physical activity while on antiretroviral therapy

Revista da Sociedade Brasileira de Medicina Tropical, 2011
INTRODUCTION: Lipodystrophy is related to the use of highly active antiretroviral therapy (HAART) and can cause aesthetic stigma and increase the risk of developing cardiovascular diseases.
Aline Francielle Mota Segatto, Ismael Forte Freitas Junior, Vanessa Ribeiro dos Santos, Kelly Cristina Pinto Alves, Dulce Aparecida Barbosa, Alexandre Martins Portelinha Filho, Henrique Luiz Monteiro   +6 more
doaj   +1 more source

Leptin decreases de novo lipogenesis in patients with lipodystrophy.

JCI Insight, 2020
De novo lipogenesis (DNL) plays a role in the development of hepatic steatosis. In humans with lipodystrophy, reduced adipose tissue causes lower plasma leptin, insulin resistance, dyslipidemia and ectopic triglyceride (TG) accumulation.
Annah P. Baykal, E. Parks, R. Shamburek, M. M. Syed-Abdul, S. Chacko, E. Cochran, M. Startzell, A. Gharib, R. Ouwerkerk, Khaled Z. Abd-Elmoniem, P. Walter, M. Walter, R. Muniyappa, S. Chung, Rebecca J. Brown   +14 more
semanticscholar   +1 more source

Implementing a tenofovir-based first-line regimen in rural Lesotho: clinical outcomes and toxicities after two years. [PDF]

, 2011
The latest World Health Organization guidelines recommend replacing stavudine with tenofovir or zidovudine in first-line antiretroviral therapy in resource-limited settings.
Birkus, Brinkman, Callaghan, Cohen, Davidson, Ford, Gallant, Gallant, Grim, Hawkins, Mills, Pozniak, Stone   +12 more
core   +2 more sources

Lipodystrophy among HIV-Infected Patients Attending Care and Treatment Clinics in Dar es Salaam

AIDS Research and Treatment, 2017
Background. HIV infection and long-term HAART use are associated with metabolic and morphological changes. We assessed prevalence, types, and risk factors associated with lipodystrophy among HIV-infected adults attending CTC in Dar es Salaam, Tanzania ...
Marina Njelekela, Rose Mpembeni, Alfa Muhihi, Nzovu Ulenga, Eric Aris, Deodatus Kakoko   +5 more
doaj   +1 more source

Cytokine profile and clinical metabolic alterations in HIV-1 infected individuals with and without lipodistrophy

Journal of Venomous Animals and Toxins including Tropical Diseases, 2007
The extensive use of Highly Active Antiretroviral Therapy (HAART) has transformed HIV infection into a chronic condition. Thus, metabolic alterations including lipodystrophy and dyslipidemia have been associated with the use of such medications.
L. C. R. Pontes-Cardoso, L. R. Souza, M. T. S. Peraçoli, P. C. M. Pereira   +3 more
doaj   +1 more source

Prevalence, Risk Factors, and Clinical Characteristics of Lipodystrophy in Insulin-Treated Patients with Diabetes: An Old Problem in a New Era of Modern Insulin

Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy, 2020
Background Lipodystrophy has been reported as a common complication in insulin-treated patients, which could lead to unexplained hypoglycemia and suboptimal glycemic control.
Y. Thewjitcharoen, Hussamon Prasartkaew, Phatharaporn Tongsumrit, Saruda Wongjom, Chatnapa Boonchoo, Siriwan Butadej, Soontaree Nakasatien, Krittadhee Karndumri, Veekij Veerasomboonsin, S. Krittiyawong, T. Himathongkam   +10 more
semanticscholar   +1 more source

Cost and cost-effectiveness of switching from d4T or AZT to a TDF-based first-line regimen in a resource-limited setting in rural Lesotho [PDF]

, 2011
Article approval pendingLatest World Health Organization guidelines recommend shifting away from Stavudine (d4T)-based regimens due to severe side effects.
Bygrave, Helen, Cleary, Susan, Ford, Nathan, Gadot, Laurent, Goemaere, Eric, Hilderbrand, Katherine, Jouquet, Guillaume, Kranzer, Katharina, Lee, Janice, Makakole, Lipontso, Trivino, Laura, Vlahakis, Natalie   +11 more
core   +2 more sources

Inherited and acquired lipodystrophies: molecular-genetic and autoimmune mechanisms

Ожирение и метаболизм, 2018
Lipodystrophy syndromes form a heterogenous group of inherited or acquired rare disorders, characterized by total (generalized lipodystrophy) or partial fat loss (partial lipodystrophy), usually accompanied by different metabolic disorders.
Ekaterina L. Sorkina, Anatoly N. Tiulpakov   +1 more
doaj   +1 more source

Congenital Generalized Lipoatrophy (Berardinelli-Seip Syndrome) Type 1: Description of Novel AGPAT2 Homozygous Variants Showing the Highly Heterogeneous Presentation of the Disease

Frontiers in Endocrinology, 2020
Berardinelli-Seip congenital lipoatrophy (BSCL) is characterized by near total fat atrophy, associated with the progressive development of metabolic complications. BSCL type 1 (BSCL1) is caused by mutations in AGPAT2, encoding 1-acylglycerol-3phosphate-O-
Giovanni Ceccarini, Silvia Magno, Caterina Pelosini, Caterina Pelosini, Federica Ferrari, Maria Rita Sessa, Gaia Scabia, Gaia Scabia, Margherita Maffei, Margherita Maffei, Isabelle Jéru, Isabelle Jéru, Olivier Lascols, Olivier Lascols, Corinne Vigouroux, Corinne Vigouroux, Corinne Vigouroux, Ferruccio Santini   +17 more
doaj   +1 more source