Results 71 to 80 of about 39,706 (298)

Mesenteric lipodystrophy. [PDF]

Journal of Clinical Pathology, 1993
Three cases of mesenteric lipodystrophy with a wide range of clinicopathological features are reported. Mesenteric lipodystrophy may present as an acute abdomen or with non-specific upper abdominal symptoms. Routine biochemical and haematological investigations are within normal limits.
M S, Bashir, C R, Abbott
openaire   +2 more sources

Clinical and Molecular Prevalence of Lipodystrophy in an Unascertained Large Clinical Care Cohort

Diabetes, 2019
Lipodystrophies are a group of disorders characterized by absence or loss of adipose tissue and abnormal fat distribution, commonly accompanied by metabolic dysregulation.
C. Gonzaga‐Jauregui, Wenzhen Ge, J. Staples, C. V. van Hout, A. Yadav, Ryan D. Colonie, J. Leader, H. L. Kirchner, Michael F. Murray, J. Reid, David J. Carey, J. Overton, A. Shuldiner, O. Gottesman, Steve Gao, J. Gromada, A. Baras, J. Altarejos   +17 more
semanticscholar   +1 more source

Complement C3 variant and the risk of age-related macular degeneration [PDF]

, 2007
Background: Age-related macular degeneration is the most common cause of blindness in Western populations. Susceptibility is influenced by age and by genetic and environmental factors.
Armbrecht, AM, Bird, AC, Clayton, DG, Deary, IJ, Dhillon, B, Genetic Factors AMD Study G, Hayward, C, Khan, JC, Matharu, BK, Moore, AT, Morgan, J, Redmond, E, Sepp, T, Shahid, H, Thurlby, DA, Wright, AF, Yates, JRW   +16 more
core   +1 more source

Targeting Seipin to Alleviate Hepatic Steatosis in Zebrafish (Danio Rerio)

Advanced Science, EarlyView.
Seipin plays a crucial role in lipid metabolism. Seipin overexpression ameliorates high‐fat‐diet‐induced hepatic steatosis and enhances growth in zebrafish. Mechanistically, Seipin interacts with Plin2 to promote Plin2 degradation and enhances phosphatidylcholine synthesis via Seipin/CCTα/CHPT interactions.
Weijia Li, Yanan Shen, Zengqi Zhao, Baolin Li, Shunlang Wen, Rui Zhan, Qinghui Ai   +6 more
wiley   +1 more source

Dynamic expression of lamin B1 during adult neurogenesis in the vertebrate brain

Developmental Dynamics, EarlyView.
Abstract Background In mammals, specific brain regions such as the dentate gyrus (DG) of the hippocampus and the subventricular zone (SVZ) of the lateral ventricles harbor adult neural stem/progenitor cells (ANSPCs) that give rise to new neurons and contribute to structural and functional brain plasticity.
Diana Zhilina, Lizbeth A. Bolaños Castro, Juan Sebastian Eguiguren, Sara Zocher, Anne Karasinsky, Dimitri Widmer, Alexandre Espinós, Victor Borrell, Michael Brand, Kyoko Miura, Oliver Zierau, Maximina H. Yun, Tomohisa Toda   +12 more
wiley   +1 more source

Body image in women with HIV: a cross-sectional evaluation

AIDS Research and Therapy, 2006
Background HIV lipodystrophy syndrome is a recognized complication of potent antiretroviral therapy and is characterized by often dramatic changes in various body fat stores, both central and peripheral.
Becerra Karen, Lee Daniel, Harrity Shawn, Huang Jeannie S, Santos Rosanne, Mathews W Christopher   +5 more
doaj   +1 more source

Congenital generalized lipodystrophy [PDF]

Jornal de Pediatria, 2004
To present the major clinical and biochemical characteristics of congenital generalized lipodystrophy.Eight infants with congenital generalized lipodystrophy were identified at the Endocrine and Nutritional Pediatric Disease Outpatient Clinics at Hospital de Clínicas, Universidade Federal de Minas Gerais (UFMG).
Cristiane de Freitas Cunha, Joel Alves Lamounier, Alexandre Costa Val, Rocksane de Carvalho Norton, Rosângela Diamante, Paulo Pimenta Figueiredo Filho, Ennio Leão   +6 more
openaire   +3 more sources

Role of a Critical Visceral Adipose Tissue Threshold (CVATT) in Metabolic Syndrome: Implications for Controlling Dietary Carbohydrates: A Review [PDF]

, 2004
There are likely many scenarios and pathways that can lead to metabolic syndrome. This paper reviews mechanisms by which the accumulation of visceral adipose tissue (VAT) may contribute to the metabolic syndrome, and explores the paradigm of a critical ...
Freedland, Eric S.
core   +5 more sources

Diagnosis, treatment and management of lipodystrophy: the physician perspective on the patient journey

Orphanet Journal of Rare Diseases
Background Lipodystrophy syndromes are a heterogeneous group of rare, life-limiting diseases characterized by a selective loss of adipose tissue and severe metabolic complications.
Nivedita Patni, Craig Chard, David Araújo-Vilar, Helen Phillips, David A. Magee, Baris Akinci   +5 more
doaj   +1 more source

The Bidirectional Relationship Between Obstructive Sleep Apnea and Metabolic Disease [PDF]

, 2018
Obstructive sleep apnea (OSA) is a common sleep disorder, effecting 17% of the total population and 40–70% of the obese population (1, 2). Multiple studies have identified OSA as a critical risk factor for the development of obesity, diabetes, and ...
Arble, Deanna M., Framnes, Sarah N.
core   +3 more sources