Results 21 to 30 of about 17,237 (190)

Comparative analysis of numerical density of ganglion cells with certain content of lipofuscin pigment in the parts of symphatetic trunk during the aging [PDF]

open access: yesPraxis Medica, 2015
The neurons of the sympathetic trunk as well as the other nerve cells undergo of many changes during life. The most striking of these morphological changes, during normal aging, is the accumulation of lipofuscin-filled vacuoles or neuromelanin ...
Filipović T.   +5 more
doaj   +1 more source

Parity-Dependent Hemosiderin and Lipofuscin Accumulation in the Reproductively Aged Mouse Ovary

open access: yesAnalytical Cellular Pathology, 2018
The progressive decline of the ovarian follicle pool leads to reproductive ageing. The latter is accompanied by age-related disorders, including various types of cancer.
Ulises Urzua   +4 more
doaj   +1 more source

Immunochemical detection of a lipofuscin-like fluorophore derived from malondialdehyde and lysine

open access: yesJournal of Lipid Research, 2001
The accumulation of fluorescent age pigment or lipofuscin is a frequently observed age-associated cellular alteration in a variety of postmitotic cells of many species. These pigments are observed within granules composed, in part, of damaged protein and
Satoshi Yamada   +9 more
doaj   +1 more source

Automatic quantification of myocardial remodeling features in human ventricular tissue from label-free microscopy

open access: yesSTAR Protocols, 2023
Summary: The procedures used routinely for collagen and lipofuscin evaluation are, in many cases, qualitative, observer dependent, and disregard spatial distribution.
Laura García-Mendívil   +4 more
doaj   +1 more source

A case report on lipofuscin deposition in a graft biopsy two years after kidney transplantation: an insignificant bystander or a pathogenic benefactor?

open access: yesBMC Nephrology, 2019
Background Lipofuscin deposition is a characteristic manifestation of aging. There is very limited literature in humans and in animals describing these deposits in native kidneys.
Vivian W. Y. Leung   +3 more
doaj   +1 more source

LIPOFUSCIN ROLE IN INVOLUTIVE AND PATHOLOGICAL PROCESSES [PDF]

open access: yesСаратовский научно-медицинский журнал, 2009
The modern data on the lipofuscin role in the processes of intracellular exchange have been analysed in the review. The ambiguity of the interpretation of lipofuscin accumulation according to its importance in involutive and pathological processes has ...
Maslyakova, A.A. Efimov
doaj  

Cannabinoid Receptor 2 Alters Social Memory and Microglial Activity in an Age-Dependent Manner

open access: yesMolecules, 2021
Physiological brain aging is characterized by gradual, substantial changes in cognitive ability, accompanied by chronic activation of the neural immune system.
Joanna Agnieszka Komorowska-Müller   +4 more
doaj   +1 more source

Cell Autofluorescence and Lipofuscin [PDF]

open access: yesFrontiers in Medicine, 2015
I was greatly impressed by an article recently published in Nature Methods (1), in which intracellular autofluorescence was characterized as a biomarker for epithelial cancer stem cells (CSCs). Interestingly, this epithelial CSC-specific autofluorescence was also associated with a highly invasive and chemoresistant phenotype.
openaire   +4 more sources

Exacerbated Age-Related Hippocampal Alterations of Microglia Morphology, β-Amyloid and Lipofuscin Deposition and Presenilin Overexpression in Per1−/−-Mice

open access: yesAntioxidants, 2021
In humans, alterations of circadian rhythms and autophagy are linked to metabolic, cardiovascular and neurological dysfunction. Autophagy constitutes a specific form of cell recycling in many eukaryotic cells.
Jan Hendrik Börner   +2 more
doaj   +1 more source

Effect of season and behavioral activity on the hypopharyngeal glands of three honey bee Apis mellifera L. races under stressful climatic conditions of central Saudi Arabia [PDF]

open access: yesJournal of Hymenoptera Research, 2019
Honey production gains are needed to deal with high demand in Saudi Arabia. The honey bee races are facing stressful hot-arid weather conditions that can affect different aspects of physiology and behavior.
Hussain Ali   +5 more
doaj   +3 more sources

Home - About - Disclaimer - Privacy